2016
Indoor microbial communities: Influence on asthma severity in atopic and nonatopic children
Dannemiller KC, Gent JF, Leaderer BP, Peccia J. Indoor microbial communities: Influence on asthma severity in atopic and nonatopic children. Journal Of Allergy And Clinical Immunology 2016, 138: 76-83.e1. PMID: 26851966, PMCID: PMC5357886, DOI: 10.1016/j.jaci.2015.11.027.Peer-Reviewed Original ResearchConceptsAsthma severityAtopic statusAtopic childrenNonatopic childrenLogistic regressionMicrobial exposureChildhood asthma severityCohort of childrenAsthmatic childrenAllergenic fungal speciesTotal fungal concentrationsSeverityHouse dustCryptococcus speciesExposure metricsChildrenT-testCohortQuantitative PCRFungal concentrationsAssociationExposureNext-generation DNA sequencingStatusRegression
2013
Household Levels of Nitrogen Dioxide and Pediatric Asthma Severity
Belanger K, Holford TR, Gent JF, Hill ME, Kezik JM, Leaderer BP. Household Levels of Nitrogen Dioxide and Pediatric Asthma Severity. Epidemiology 2013, 24: 320-330. PMID: 23337243, PMCID: PMC3686297, DOI: 10.1097/ede.0b013e318280e2ac.Peer-Reviewed Original ResearchConceptsAsthma severityNight symptomsAsthma morbiditySeverity scoreNO2 exposureHigher asthma severity scoresFrequency of wheezeIndoor NO2 exposurePediatric asthma severityRescue medication useIndoor allergen exposureAsthma severity scoreAdverse respiratory effectsDose-dependent increaseYears of ageInner-city childrenLogistic regression modelsRescue medicationActive asthmaAllergen exposureAsthmatic childrenMedication useRespiratory effectsChildren 5Health outcomes
2012
Household mold and dust allergens: Exposure, sensitization and childhood asthma morbidity
Gent JF, Kezik JM, Hill ME, Tsai E, Li DW, Leaderer BP. Household mold and dust allergens: Exposure, sensitization and childhood asthma morbidity. Environmental Research 2012, 118: 86-93. PMID: 22863552, PMCID: PMC3604733, DOI: 10.1016/j.envres.2012.07.005.Peer-Reviewed Original ResearchConceptsRisk of wheezeSpecific allergen sensitizationRescue medication useChildhood asthma morbidityAsthma severity scoreMedication useAllergen sensitizationPersistent coughAsthma morbiditySeverity scoreHigher asthma severity scoresCommon household allergensCommon indoor allergensFel d 1Der p 1Asthma exacerbationsAllergen exposureLevel of exposureAsthmatic childrenDer pAllergy testingIndoor allergensSchool-aged childrenPet allergensDust allergensEffects of Ambient Pollen Concentrations on Frequency and Severity of Asthma Symptoms Among Asthmatic Children
DellaValle CT, Triche EW, Leaderer BP, Bell ML. Effects of Ambient Pollen Concentrations on Frequency and Severity of Asthma Symptoms Among Asthmatic Children. Epidemiology 2012, 23: 55-63. PMID: 22082997, PMCID: PMC3246281, DOI: 10.1097/ede.0b013e31823b66b8.Peer-Reviewed Original ResearchConceptsShortness of breathRescue medication useAsthma maintenance medicationsMaintenance medicationPersistent coughSensitized childrenChest tightnessNight symptomsAsthmatic childrenMedication usePollen exposureSeverity of asthmaDaily respiratory symptomsWeed pollenLogistic regression analysisLow exposureSeparate logistic regression analysesAsthmatic symptomsRespiratory symptomsDaily symptomsAntibiotic useSymptom outcomesDaily ambientMedicationsAmbient pollen concentrations
2009
Household airborne Penicillium associated with peak expiratory flow variability in asthmatic children
Bundy KW, Gent JF, Beckett W, Bracken MB, Belanger K, Triche E, Leaderer BP. Household airborne Penicillium associated with peak expiratory flow variability in asthmatic children. Annals Of Allergy Asthma & Immunology 2009, 103: 26-30. PMID: 19663123, PMCID: PMC2746059, DOI: 10.1016/s1081-1206(10)60139-1.Peer-Reviewed Original ResearchConceptsPeak expiratory flow variabilityExpiratory flow variabilityAsthmatic childrenAirway hyperreactivityPeak expiratory flowYears of ageLogistic regression modelsAsthma prevalencePhysician diagnosisExpiratory flowChildren 6HyperreactivityChildrenAirborne mold concentrationsRegression modelsAgeCommon moldsIndoor fungiExposureMold concentrationsHomeAsthmaAirborne fungiTotal moldPrevalence
2001
Use of Health Services by Insurance Status Among Children With Asthma
Ortega A, Belanger K, Paltiel A, Horwitz S, Bracken M, Leaderer B. Use of Health Services by Insurance Status Among Children With Asthma. Medical Care 2001, 39: 1065-1074. PMID: 11567169, DOI: 10.1097/00005650-200110000-00004.Peer-Reviewed Original ResearchConceptsPrimary care visitsHealth care useEmergency departmentInsurance statusCare visitsAsthmatic childrenMedication useCare useAsthma-related risk factorsRoutine primary care visitsProspective cohort studyHealth care visitsHealth care utilizationChildhood asthma severityPatient-provider communicationWhite childrenMedical DictionaryNew England hospitalsRace/ethnicityAsthma specialistCohort studyMedicaid childrenAsthma severityIndependent predictorsCare utilizationA childhood asthma severity scale: symptoms, medications, and health care visits
Ortega A, Belanger K, Bracken M, Leaderer B. A childhood asthma severity scale: symptoms, medications, and health care visits. Annals Of Allergy Asthma & Immunology 2001, 86: 405-413. PMID: 11345283, DOI: 10.1016/s1081-1206(10)62486-6.Peer-Reviewed Original ResearchConceptsHealth care visitsChildhood asthma severityCare visitsAsthma severityLarge-scale epidemiologic studiesAsthma severity scaleMedication useSeverity ScaleEpidemiologic studiesHome interviewsProspective cohort studyHealth care utilizationCohort studyAsthmatic childrenCare utilizationDaily symptomsInsurance statusConnecticut hospitalsGeneral populationClinimetric propertiesClinimetric validityMaternal educationClinical diagnosisParticipant characteristicsSymptomsRisk Factors for Asthma Prevalence Among Urban and Nonurban African American Children
von Maffei J, Beckett W, Belanger K, Triche E, Zhang H, Machung J, Leaderer B. Risk Factors for Asthma Prevalence Among Urban and Nonurban African American Children. Journal Of Asthma 2001, 38: 555-564. PMID: 11714078, DOI: 10.1081/jas-100107120.Peer-Reviewed Original ResearchConceptsRisk factorsUrban residenceAfrican American childrenMaternal cigarette smokingPhysician-diagnosed asthmaMultiple risk factorsYears of ageMaternal asthmaAsthmatic childrenAsthma prevalenceCigarette smokingAsthmaAmerican childrenAfrican American mothersIdentifiable factorsChildrenAmerican mothersResidenceFactorsSmokingAllergyNewbornsPrevalence
1996
Asthma among Puerto Rican Hispanics: a multi-ethnic comparison study of risk factors.
Beckett W, Belanger K, Gent J, Holford T, Leaderer B. Asthma among Puerto Rican Hispanics: a multi-ethnic comparison study of risk factors. American Journal Of Respiratory And Critical Care Medicine 1996, 154: 894-899. PMID: 8887582, DOI: 10.1164/ajrccm.154.4.8887582.Peer-Reviewed Original ResearchConceptsRisk factorsPuerto Rican HispanicsSocioeconomic statusHispanic ethnicityHispanic mothersEnvironmental tobacco smoke exposureIndependent risk factorPhysician-diagnosed asthmaPrevalence of asthmaTobacco smoke exposureStrong risk factorAfrican American ethnicityEnvironmental risk factorsYr of ageLow socioeconomic statusStudy of asthmaNon-Hispanic whitesMo of ageActive smokingAsthmatic childrenSmoke exposureChildhood asthmaCigarette smokersMaternal ageMaternal history
1995
The accuracy of environmental tobacco smoke exposure measures among asthmatic children
Emerson J, Hovell M, Meltzer S, Zakarian J, Hofstetter C, Wahlgren D, Leaderer B, Meltzer E. The accuracy of environmental tobacco smoke exposure measures among asthmatic children. Journal Of Clinical Epidemiology 1995, 48: 1251-1259. PMID: 7561987, DOI: 10.1016/0895-4356(95)00021-u.Peer-Reviewed Original ResearchConceptsResidential ETS exposureETS exposureAsthmatic childrenParent-report measuresEnvironmental tobacco smoke exposureResidential exposureUrine cotinine assayTobacco smoke exposureChildren's residential exposureTest-retest reliability assessmentSmoke exposureCotinine assaysHome exposureEpidemiological investigationsClinical programsExposure measuresConstruct validity testParent reportExposureDiscriminant validityChildrenReportNicotineMeasures