2023
Beneficial Effect of Societal Factors on APOE-ε2 and ε4 Carriers’ Brain Health: A Systematic Review
Aravena J, Lee J, Schwartz A, Nyhan K, Wang S, Levy B. Beneficial Effect of Societal Factors on APOE-ε2 and ε4 Carriers’ Brain Health: A Systematic Review. The Journals Of Gerontology Series A 2023, 79: glad237. PMID: 37792627, PMCID: PMC10803122, DOI: 10.1093/gerona/glad237.Peer-Reviewed Original ResearchBrain healthSocietal factorsAPOE ε4Cognitive outcomesApolipoprotein E ε4APOE ε4 carriersAPOE ε2Beneficial effectsΕ4 carriersSystematic reviewAPOE ε4 allele carriersHigh schoolAPOE ε2 carriersDetrimental effectsBasic needsHealthy People 2030Beneficial impactExternal stimuliHarmful impactSDH categoriesInclusion criteriaAllele carriersAlzheimer's diseaseCommunity-level policySocial determinants
2020
Positive Age Beliefs Lead to Lower Dementia Risk Even Among Older Persons With High-Risk Gene
Levy B, Slade M, Pietrzak R, Ferrucci L. Positive Age Beliefs Lead to Lower Dementia Risk Even Among Older Persons With High-Risk Gene. Innovation In Aging 2020, 4: 597-597. PMCID: PMC7742059, DOI: 10.1093/geroni/igaa057.2009.Peer-Reviewed Original ResearchOlder individualsLower dementia riskStrong risk factorRetirement Study participantsHigh-risk genesΕ4 variantDementia riskRisk factorsΕ4 carriersAPOE ε4High riskDementiaOlder personsStudy participantsAPOE geneProtective factorsRelevant covariatesRiskTotal sampleBaselineCurrent studyCohortΕ4Individuals
2018
Positive age beliefs protect against dementia even among elders with high-risk gene
Levy BR, Slade MD, Pietrzak RH, Ferrucci L. Positive age beliefs protect against dementia even among elders with high-risk gene. PLOS ONE 2018, 13: e0191004. PMID: 29414991, PMCID: PMC5802444, DOI: 10.1371/journal.pone.0191004.Peer-Reviewed Original Research