Exposome-Wide Ranking to Uncover Environmental Chemicals Associated with Dyslipidemia: A Panel Study in Healthy Older Chinese Adults from the BAPE Study.
Ding E, Deng F, Fang J, Liu J, Yan W, Yao Q, Miao K, Wang Y, Sun P, Li C, Liu Y, Dong H, Dong L, Zhang X, Lu Y, Lin X, Ding C, Li T, Shi Y, Cai Y, Liu X, Godri Pollitt K, Ji J, Tong S, Tang S, Shi X. Exposome-Wide Ranking to Uncover Environmental Chemicals Associated with Dyslipidemia: A Panel Study in Healthy Older Chinese Adults from the BAPE Study. Environmental Health Perspectives 2024, 132: 97005. PMID: 39240788, PMCID: PMC11379127, DOI: 10.1289/ehp13864.Peer-Reviewed Original ResearchConceptsDyslipidemia markersCardiovascular diseaseMulti-omicsMarkers of dyslipidemiaExamination of cytokinesMeasurement of cytokinesSerum lipidomeSystemic inflammationMulti-omics profilingCardiac functionDyslipidemiaPrimary preventionClinical measuresSerumChinese adultsBlood transcriptomeImpact spectraCytokinesExposome-wide association studyInflammationMarkersBiomolecular pathwaysAssociationHealthy older adultsElectrocardiogram[Association of sleep duration and physical exercise with dyslipidemia in older adults aged 80 years and over in China].
Wu B, Li Y, Xu L, Zhang Z, Zhou J, Wei Y, Chen C, Wang J, Wu C, Li Z, Hu Z, Long F, Wu Y, Hu X, Li K, Li F, Luo Y, Liu Y, Lyu Y, Shi X. [Association of sleep duration and physical exercise with dyslipidemia in older adults aged 80 years and over in China]. Chinese Journal Of Epidemiology 2024, 45: 48-55. PMID: 38228524, DOI: 10.3760/cma.j.cn112338-20231007-00207.Peer-Reviewed Original ResearchConceptsRestricted cubic splinesPhysical exerciseSleep durationPerson yearsDose-response relationshipAssociation of sleep durationPositive dose-response relationshipImpact of sleep durationBlood lipid testRisk of dyslipidemiaAverage sleep durationRestricted cubic spline functionsCompeting risk modelBaseline surveyBiomarkers Cohort StudyCases of dyslipidemiaLipid testingFasting venous blood samplesInteraction of sleep durationCohort studyExerciseCompetitive risk model analysisDemographic characteristicsIncidence densityStudy subjects