Infectious Diseases
Laboratory Science
The Department of Epidemiology of Microbial Diseases has an established record of public health discovery through laboratory science. In the school’s first century, YSPH led the fight against poliomyelitis, housed the Arbovirus Research Unit which moved from the Rockefeller Foundation to Yale in 1964 (and was home to Nobel prize-winning scientist Max Theiler and other prominent scientists), as well as the WHO serum bank. Today, Yale is home to several modern laboratories that address vector-borne diseases transmitted by tsetse flies, ticks, mosquitoes and sand flies. In addition, our scientists are pursuing solutions to respiratory ailments, antibiotic resistance, diagnostic testing, vaccine development and infections related to STIs and intravenous drug use.
Recent Publications
2024
- Factors influencing adverse events following COVID-19 vaccination.Villanueva P, McDonald E, Croda J, Croda MG, Dalcolmo M, Dos Santos G, Jardim B, Lacerda M, Lynn DJ, Marshall H, Oliveira RD, Rocha J, Sawka A, Val F, Pittet LF, Messina NL, Curtis N. Hum Vaccin Immunother. 2024 Dec 31; 2024 Mar 6. PMID: 38445666.
- A scoping review of active, participant centred, digital adverse events following immunization (AEFI) surveillance of WHO approved COVID-19 vaccines: A Canadian immunization Research Network study.Serhan M, Psihogios A, Kabir N, Bota AB, Mithani SS, Smith DP, Zhu DT, Greyson D, Wilson S, Fell D, Top KA, Bettinger JA, Wilson K. Hum Vaccin Immunother. 2024 Dec 31; 2024 Feb 19. PMID: 38374618.
- Effectiveness of the fourth dose of COVID-19 vaccines against severe COVID-19 among adults 40 years or older in Brazil: a population-based cohort study.Lazar Neto F, Hitchings MDT, Amin AB, de França GVA, Lind ML, Scaramuzzini Torres MS, Tsuha DH, de Oliveira RD, Cummings DAT, Dean NE, Andrews JR, Ko AI, Croda J, Ranzani OT. Lancet Reg Health Am. 2024 Jun; 2024 May 3. PMID: 38737773.
- Anti-stigma interventions in low-income and middle-income countries: a systematic review.Majeed T, Hopkin G, Wang K, Nepal S, Votruba N, Gronholm P, Gurung D, Semrau M, Bagade T, Farina N, Musyimi C, Pingani L, Breuer E, Lund C, Thornicroft G, Evans-Lacko S. EClinicalMedicine. 2024 Jun; 2024 Apr 26. PMID: 38707913.
- Sociodemographic correlates of late HIV diagnosis among men who have sex with men (MSM) in Ghana.Aidoo-Frimpong G, Tong G, Akyirem S, Abwoye DN, Nwanaji-Enwerem U, López DJ, Wilton L, Nelson LE. AIDS Care. 2024 Jun; 2024 Mar 9. PMID: 38460152.
- Characteristics of healthcare personnel with SARS-CoV-2 infection: 10 emerging infections program sites in the United States, April 2020-December 2021.Chea N, Eure T, Alkis Ramirez R, Zlotorzynska M, Blazek GT, Nadle J, Lee J, Czaja CA, Johnston H, Barter D, Kellogg M, Emanuel C, Meek J, Brackney M, Carswell S, Thomas S, Fridkin SK, Wilson LE, Perlmutter R, Marceaux-Galli K, Fell A, Lovett S, Lim S, Lynfield R, Shrum Davis S, Phipps EC, Sievers M, Dumyati G, Myers C, Hurley C, Licherdell E, Pierce R, Ocampo VLS, Hall EW, Wilson C, Adre C, Kirtz E, Markus TM, Billings K, Plumb ID, Abedi GR, James-Gist J, Magill SS, Grigg CT. Infect Control Hosp Epidemiol. 2024 May 21; 2024 May 21. PMID: 38770586.
- Impact of COVID-19 on women living with HIV who are survivors of intimate partner violence.Zhang X, Price CR, Pope AS, Sullivan TP, Meyer JP. BMC Public Health. 2024 May 20; 2024 May 20. PMID: 38769576.
- Factors associated with differential seropositivity to Leptospira interrogans and Leptospira kirschneri in a high transmission urban setting for leptospirosis in Brazil.de Oliveira D, Khalil H, Almerinda G Palma F, Santana R, Nery N Jr, C Quintero-Vélez J, Zeppelini CG, Almeida do Sacramento G, Cruz JS, Lustosa R, Santana Ferreira I, Carvalho-Pereira T, Diggle PJ, Wunder EA Jr, I Ko A, Alzate Lopez Y, Begon M, G Reis M, Costa F. PLoS Negl Trop Dis. 2024 May 17; 2024 May 17. PMID: 38758957.
- Persistent and multiclonal malaria parasite dynamics despite extended artemether-lumefantrine treatment in children.Goodwin J, Kajubi R, Wang K, Li F, Wade M, Orukan F, Huang L, Whalen M, Aweeka FT, Mwebaza N, Parikh S. Nat Commun. 2024 May 7; 2024 May 7. PMID: 38714692.
- An mHealth Intervention for Gay and Bisexual Men's Mental, Behavioral, and Sexual Health in a High-Stigma, Low-Resource Context (Project Comunică): Protocol for a Randomized Controlled Trial.Leluțiu-Weinberger C, Filimon ML, Hoover D, Lixandru M, Hanu L, Dogaru B, Kovacs T, Fierbințeanu C, Ionescu F, Manu M, Mariș A, Pană E, Dorobănțescu C, Streinu-Cercel A, Pachankis JE. JMIR Res Protoc. 2024 May 6; 2024 May 6. PMID: 38709550.
- Assessing Direct and Spillover Effects of Intervention Packages in Network-randomized Studies.Buchanan AL, Hernández-Ramírez RU, Lok JJ, Vermund SH, Friedman SR, Forastiere L, Spiegelman D. Epidemiology. 2024 May 6; 2024 May 6. PMID: 38709023.
- Impact and cost-effectiveness of the 6-month BPaLM regimen for rifampicin-resistant tuberculosis in Moldova: A mathematical modeling analysis.James LP, Klaassen F, Sweeney S, Furin J, Franke MF, Yaesoubi R, Chesov D, Ciobanu N, Codreanu A, Crudu V, Cohen T, Menzies NA. PLoS Med. 2024 May; 2024 May 3. PMID: 38701084.
- Modeled estimates of HIV-serodifferent couples in tuberculosis-affected households in four sub-Saharan African countries.Zhang M, Tseng AS, Anguzu G, Barnabas RV, Davis JL, Mujugira A, Flaxman AD, Ross JM. PLOS Glob Public Health. 2024; 2024 May 2. PMID: 38696500.
- A supervised Bayesian factor model for the identification of multi-omics signatures.Gygi JP, Konstorum A, Pawar S, Aron E, Kleinstein SH, Guan L. Bioinformatics. 2024 May 2. PMID: 38603606.
- Metagenomics to improve infectious disease diagnostics in low- and middle-income countries.Jamiu A, Chaguza C. Nat Microbiol. 2024 May. PMID: 38714760.
- Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality.Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Haddad EK, Reed EF, Kraft M, McComsey GA, Metcalf JP, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar WL, Maecker HT, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Sekaly RP, Ehrlich LI, Fourati S, Peters B, Kleinstein SH, Guan L. J Clin Invest. 2024 May 1; 2024 May 1. PMID: 38690733.
- Air pollution changes due to COVID-19 lockdowns and attributable mortality changes in four countries.Ma Y, Nobile F, Marb A, Dubrow R, Kinney PL, Peters A, Stafoggia M, Breitner S, Chen K. Environ Int. 2024 May; 2024 Apr 16. PMID: 38640613.
- An update on clinical presentation and responses to therapy of patients with hereditary hypophosphatemic rickets with hypercalciuria (HHRH).Zhu Z, Bo-Ran Ho B, Chen A, Amrhein J, Apetrei A, Carpenter TO, Lazaretti-Castro M, Colazo JM, McCrystal Dahir K, Geßner M, Gurevich E, Heier CA, Simmons JH, Hunley TE, Hoppe B, Jacobsen C, Kouri A, Ma N, Majumdar S, Molin A, Nokoff N, Ott SM, Peña HG, Santos F, Tebben P, Topor LS, Deng Y, Bergwitz C. Kidney Int. 2024 May; 2024 Feb 15. PMID: 38364990.
- Using Data-To-Care Strategies to Optimize the HIV Care Continuum in Connecticut: Results From a Randomized Controlled Trial.Machavariani E, Miceli J, Altice FL, Fanfair RN, Speers S, Nichols L, Jenkins H, Villanueva M. J Acquir Immune Defic Syndr. 2024 May 1. PMID: 38324241.
- Social support as a mediator between mental health and stigma among newly HIV-positive men who have sex with men.Zhao Y, Khoshnood K, Sheng Y. Int J STD AIDS. 2024 May; 2024 Feb 5. PMID: 38314565.
- Digital Interventions to Support Lung Cancer Screening: A Systematic Review.Odole IP, Andersen M, Richman IB. Am J Prev Med. 2024 May; 2024 Jan 20. PMID: 38246408.
- High prevalence of impaired glucose metabolism among children and adolescents living with HIV in Ghana.Ayanful-Torgby R, Shabanova V, Essuman AA, Boafo E, Aboagye F, Al-Mahroof Y, Amponsah J, Tetteh JKA, Amoah LE, Paintsil E. HIV Med. 2024 May; 2024 Jan 19. PMID: 38240173.
- The Association of Prescribed Opioids and Incident Cardiovascular Disease.Sung ML, Eden SK, Becker WC, Crystal S, Duncan MS, Gordon KS, Kerns RD, Kundu S, Freiberg M, So-Armah KA, Edelman EJ. J Pain. 2024 May; 2023 Nov 27. PMID: 38029949.
- The full value of immunisation against respiratory syncytial virus for infants younger than 1 year: effects beyond prevention of acute respiratory illness.Feikin DR, Karron RA, Saha SK, Sparrow E, Srikantiah P, Weinberger DM, Zar HJ. Lancet Infect Dis. 2024 May; 2023 Nov 21. PMID: 38000374.
- Prevalence and Correlates of Physical Inactivity Among Individuals with HIV During the First COVID-19 Wave: A Cross-sectional Survey.Harsono D, Deng Y, Chung S, Barakat LA, Friedland G, Villanueva M, Yager JE, Justen M, Edelman EJ. AIDS Behav. 2024 May; 2023 Oct 12. PMID: 37824037.