Featured Publications
Joint analysis of repeatedly observed continuous and ordinal measures of disease severity
Gueorguieva RV, Sanacora G. Joint analysis of repeatedly observed continuous and ordinal measures of disease severity. Statistics In Medicine 2006, 25: 1307-1322. PMID: 16217846, DOI: 10.1002/sim.2270.Peer-Reviewed Original Research
2020
Two‐part models for repeatedly measured ordinal data with “don't know” category
Gueorguieva R, Buta E, Morean M, Krishnan‐Sarin S. Two‐part models for repeatedly measured ordinal data with “don't know” category. Statistics In Medicine 2020, 39: 4574-4592. PMID: 32909252, PMCID: PMC8025667, DOI: 10.1002/sim.8739.Peer-Reviewed Original ResearchConceptsAdaptive Gaussian quadratureCorrelated random effectsSAS PROC NLMIXEDOrdinal dataMaximum likelihood estimationTerms of biasStatistical dependenceNominal modelGaussian quadraturePROC NLMIXEDLikelihood estimationPartial orderingEstimation algorithmTwo-part modelModel formulationSimulation studyRandom effectsPredictor effectsSubmodelsOrdinal natureFormulationNLMIXEDQuadratureModelOrdering
2011
Using Computational Patients to Evaluate Illness Mechanisms in Schizophrenia
Hoffman RE, Grasemann U, Gueorguieva R, Quinlan D, Lane D, Miikkulainen R. Using Computational Patients to Evaluate Illness Mechanisms in Schizophrenia. Biological Psychiatry 2011, 69: 997-1005. PMID: 21397213, PMCID: PMC3105006, DOI: 10.1016/j.biopsych.2010.12.036.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognition DisordersComputer SimulationFemaleHumansMaleMental RecallMiddle AgedModels, BiologicalSchizophreniaConceptsPrediction-error signallingStory recall taskIllness mechanismsEpisodic memoryRecall taskAssociated emotionsNarrative memoryNarrative languageDopamine neuromodulationDisparate symptomsNarrative understandingHealthy control subjectsDisorganized speechMemorySchizoaffective disorderComputational modelNeural network modelParental educationSchizophreniaCrime storiesPrediction errorDelusionsControl subjectsEmotionsNetwork model