2025
Study protocol for the Health Outcomes in Pregnancy and Early Childhood (HOPE) Study: A mother-infant study in American Samoa
Heinsberg L, Loia M, Tasele S, Faasalele-Savusa K, Carlson J, Anesi S, Desobry K, Yuchongco E, Guevara B, Sesaga A, Iloilo A, Tofaeono V, Bryan K, Tauasosi-Posiulai T, Kershaw E, Conley Y, Weeks D, Hawley N, Muasau-Howard B. Study protocol for the Health Outcomes in Pregnancy and Early Childhood (HOPE) Study: A mother-infant study in American Samoa. PLOS ONE 2025, 20: e0326644. PMID: 40952996, PMCID: PMC12435730, DOI: 10.1371/journal.pone.0326644.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusBody mass indexHealth outcomesBurden of gestational diabetes mellitusLower risk of type 2 diabetesAmerican Samoa Department of HealthAssociated with higher body mass indexLow riskGestational diabetes statusRisk of type 2 diabetesHigher Body Mass IndexCord blood DNA methylationLongitudinal cohort studyDepartment of HealthInfant body sizePacific IslandersPeer-reviewed publicationsType 2 diabetesBlood DNA methylationInstitutional review boardAmerican SamoaPregnant womenInfant growthFollow-upMass indexAssociations between maternal and infant body composition, feeding practices, and perceived infant eating behaviour in Samoan mother–infant dyads aged 1–4 months
Bertacchi V, Daiy K, Vesi L, Faaselele-Savusa K, Duckham R, Naseri T, Soti-Ulberg C, Abraham J, Bribiescas R, Hawley N. Associations between maternal and infant body composition, feeding practices, and perceived infant eating behaviour in Samoan mother–infant dyads aged 1–4 months. Annals Of Human Biology 2025, 52: 2534349. PMID: 40762381, DOI: 10.1080/03014460.2025.2534349.Peer-Reviewed Original ResearchConceptsBaby Eating Behaviour QuestionnaireInfant body compositionFood responsivenessSatiety responsivenessInfant appetiteBody compositionMaternal perceptionProportion of infantsBMI-for-ageAged 1General appetiteInfants aged 1Initiation of breastfeedingBody composition measurementsDevelopment of obesityInfant eating behaviorsMaternal educational statusMaternal BMIBreastfed infantsInfant characteristicsInfant sexBreastfeeding patternsBreastfeeding practicesMaternal confidenceInfantsMaternal Obesity and Neonatal Death in Preterm US Pacific Islander Neonates Using 2 Analytic Approaches
Wu B, Taylor S, Hawley N, Shabanova V. Maternal Obesity and Neonatal Death in Preterm US Pacific Islander Neonates Using 2 Analytic Approaches. JAMA Network Open 2025, 8: e2528924. PMID: 40856998, PMCID: PMC12381668, DOI: 10.1001/jamanetworkopen.2025.28924.Peer-Reviewed Original ResearchConceptsFetuses-at-risk approachFetuses-at-riskPrepregnancy body mass indexBody mass indexPreterm birthGestational ageNeonatal deathPacific Islander individualsObesity class ICohort studyWeeks GAPrepregnancy obesityStratification biasIslander individualsNational Center for Health StatisticsRate of neonatal deathPopulation-based cohort studyCenter for Health StatisticsClass IDegree of prematurityMother-neonate dyadsPrevalence of obesityCox proportional hazards modelsNeonatal mortality ratePreterm birth prevalence
2024
Prediction of neonatal survival among Pacific Islander preterm births in the US
Wu B, Taylor S, Shabanova V, Hawley N. Prediction of neonatal survival among Pacific Islander preterm births in the US. PLOS ONE 2024, 19: e0316048. PMID: 39739767, PMCID: PMC11687717, DOI: 10.1371/journal.pone.0316048.Peer-Reviewed Original ResearchConceptsGestational ageNeonatal sexBirth weightNeonatal mortalityNeonatal survivalPreterm birthBorn large-for-gestational ageLarge-for-gestational ageObesity-related risk factorsPrediction of neonatal survivalPre-pregnancy obesityGroup of neonatesMortality rateNeonatal mortality rateUnited States National Center for Health StatisticsDeath data filesPacific Islander mothersPredicted survival ratesGestational weeksPre-pregnancyNeonatal deathCongenital anomaliesGestationSurvival rateRisk factorsThe milk study protocol: A longitudinal, prospective cohort study of the relationship between human milk metabolic hormone concentration, maternal body composition, and early growth and satiety development in Samoan infants aged 1–4 months
Harries V, Abraham J, Vesi L, Reupena A, Faaselele-Savusa K, Duckham R, Bribiescas R, Hawley N. The milk study protocol: A longitudinal, prospective cohort study of the relationship between human milk metabolic hormone concentration, maternal body composition, and early growth and satiety development in Samoan infants aged 1–4 months. PLOS ONE 2024, 19: e0292997. PMID: 38728264, PMCID: PMC11086876, DOI: 10.1371/journal.pone.0292997.Peer-Reviewed Original ResearchConceptsMaternal body compositionEarly infant growthBody compositionInfant growthProspective longitudinal cohortMother-infant dyadsBreastfeeding mother-infant dyadsHuman milkFingerpick blood sampleInfants aged 1Longitudinal cohortBody composition measurementsProspective cohort studyInfant feeding patternsSatiety developmentUndernourished womenSatiety responsivenessInfant satietyInfant hungerHormone leptinCohort studyHigh-income settingsMultivariate analysisEating patternsHormone transfer
2023
Cross-sectional and prospective associations between household socioeconomic resources, appetite traits, and body size among Samoan infants
Oyama S, Arslanian K, Fidow U, Naseri T, Soti-Ulberg C, Hawley N. Cross-sectional and prospective associations between household socioeconomic resources, appetite traits, and body size among Samoan infants. Appetite 2023, 185: 106519. PMID: 36870391, DOI: 10.1016/j.appet.2023.106519.Peer-Reviewed Original Research
2021
Factorial validation analysis of the Baby and Children's Eating Behavior Questionnaires in Samoa
Oyama S, Arslanian KJ, Fidow UT, Naseri T, Soti-Ulberg C, Hawley NL. Factorial validation analysis of the Baby and Children's Eating Behavior Questionnaires in Samoa. Eating Behaviors 2021, 42: 101530. PMID: 34051664, PMCID: PMC8380697, DOI: 10.1016/j.eatbeh.2021.101530.Peer-Reviewed Original ResearchConceptsBaby Eating Behaviour QuestionnaireEating Behavior QuestionnaireMonths postpartumChildren's Eating Behaviour QuestionnaireInfant feeding behaviorsMother-infant dyadsBehavior QuestionnaireCEBQ scoresPediatric obesityElimination of factorsPostpartumTime pointsFurther qualitative researchCEBQEarly childhoodPacific IslandersLongitudinal analysisNine-itemMonthsFactor structureLow internal reliabilityInternal reliabilityThree-factor structureExploratory factor analysisQuestionnaire's factor structureBody size and composition of Samoan toddlers aged 18–25 months in 2019
Oyama S, Duckham RL, Arslanian KJ, Kershaw EE, Strayer JA, Fidow UT, Naseri T, Hawley NL. Body size and composition of Samoan toddlers aged 18–25 months in 2019. Annals Of Human Biology 2021, 48: 346-349. PMID: 34340601, PMCID: PMC9912174, DOI: 10.1080/03014460.2021.1951351.Peer-Reviewed Original ResearchConceptsDual-energy X-ray absorptiometryProspective birth cohortPrimary study aimX-ray absorptiometryGreater linear growthMother-infant dyadsThigh skinfold thicknessRs373863828 genotypeAdult SamoansArm circumferenceAbdominal circumferenceHead circumferenceProtective effectGG genotypeIliac crestLower riskSkinfold thicknessBody compositionBirth cohortStudy aimMinor alleleEarly lifeMissense variantsCircumferenceEarly childhood
2020
Effect of maternal nutrient intake during 31–37 weeks gestation on offspring body composition in Samoa
Arslanian KJ, Fidow UT, Atanoa T, Naseri T, Duckham RL, McGarvey ST, Choy C, Hawley NL. Effect of maternal nutrient intake during 31–37 weeks gestation on offspring body composition in Samoa. Annals Of Human Biology 2020, 47: 587-596. PMID: 32892647, PMCID: PMC7900936, DOI: 10.1080/03014460.2020.1820078.Peer-Reviewed Original ResearchConceptsInfant body compositionDual-energy X-ray absorptiometryFood frequency questionnaireBody compositionDietary intakeBone massNutrient intakeMaternal body mass indexNewborn body compositionPregnancy dietary intakeMaternal dietary intakeOffspring body compositionMultivariable linear regression modelsBody mass indexWeeks of gestationMaternal nutrient intakeX-ray absorptiometryEnergy-dense dietPregnancy nutritionFrequency questionnaireFuture obesityInfant adiposityWeeks' gestationMass indexThird trimesterA missense variant in CREBRF, rs373863828, is associated with fat-free mass, not fat mass in Samoan infants
Arslanian KJ, Fidow UT, Atanoa T, Unasa-Apelu F, Naseri T, Wetzel AI, Pomer A, Duckham RL, McGarvey ST, Strayer JA, Kershaw EE, Weeks DE, Hawley NL. A missense variant in CREBRF, rs373863828, is associated with fat-free mass, not fat mass in Samoan infants. International Journal Of Obesity 2020, 45: 45-55. PMID: 32884101, PMCID: PMC8329753, DOI: 10.1038/s41366-020-00659-4.Peer-Reviewed Original ResearchConceptsBody mass indexDual-energy X-ray absorptiometrySamoan infantsBone massFat massLean massEarly infantsBody compositionInfant body mass indexMinor alleleDeterminants of adiposityOdds of diabetesBone mass accretionMissense variantsX-ray absorptiometryFat-free massCross-sectional analysisMore bone massCREBRF variantProspective studyHigher oddsEarly infancyInfantsAdult populationNatural history
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