2025
Study protocol for the Health Outcomes in Pregnancy and Early Childhood (HOPE) Study: A mother-infant study in American Samoa
Heinsberg L, Loia M, Tasele S, Faasalele-Savusa K, Carlson J, Anesi S, Desobry K, Yuchongco E, Guevara B, Sesaga A, Iloilo A, Tofaeono V, Bryan K, Tauasosi-Posiulai T, Kershaw E, Conley Y, Weeks D, Hawley N, Muasau-Howard B. Study protocol for the Health Outcomes in Pregnancy and Early Childhood (HOPE) Study: A mother-infant study in American Samoa. PLOS ONE 2025, 20: e0326644. PMID: 40952996, PMCID: PMC12435730, DOI: 10.1371/journal.pone.0326644.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmerican SamoaBody Mass IndexDiabetes, GestationalDNA MethylationFemaleHumansInfantInfant, NewbornLongitudinal StudiesMalePregnancyPregnancy OutcomeConceptsGestational diabetes mellitusBody mass indexHealth outcomesBurden of gestational diabetes mellitusLower risk of type 2 diabetesAmerican Samoa Department of HealthAssociated with higher body mass indexLow riskGestational diabetes statusRisk of type 2 diabetesHigher Body Mass IndexCord blood DNA methylationLongitudinal cohort studyDepartment of HealthInfant body sizePacific IslandersPeer-reviewed publicationsType 2 diabetesBlood DNA methylationInstitutional review boardAmerican SamoaPregnant womenInfant growthFollow-upMass index
2024
A group prenatal care intervention reduces gestational weight gain and gestational diabetes in American Samoan women
Hawley N, Faasalele‐Savusa K, Faiai M, Suiaunoa‐Scanlan L, Loia M, Ickovics J, Kocher E, Piel C, Mahoney M, Suss R, Trocha M, Rosen R, Muasau‐Howard B. A group prenatal care intervention reduces gestational weight gain and gestational diabetes in American Samoan women. Obesity 2024, 32: 1833-1843. PMID: 39256170, PMCID: PMC11755376, DOI: 10.1002/oby.24102.Peer-Reviewed Original ResearchConceptsGestational weight gainPostpartum weight changeGestational diabetes screeningClinically important between-group differenceDiabetes screeningGestational diabetesUsual care participantsPrenatal care interventionsMode of birthLow-risk pregnant womenPre-pregnancy obesityAmerican Samoan womenIncidence of gestational diabetesProportion of womenGestational diabetes incidenceInfant birth weightWeight gainBetween-group differencesCare interventionsCare participantsPreliminary effectivenessWeight changeRandom group assignmentDiabetes incidenceHigh-risk settings
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