2025
379. Potential clinical and economic impact of cutbacks in the United States President's Emergency Plan for AIDS Relief Program in South Africa: a modelling analysis
Gandhi A, Bekker L, Paltiel A, Hyle E, Ciaranello A, Pillay Y, Freedberg K, Neilan A. 379. Potential clinical and economic impact of cutbacks in the United States President's Emergency Plan for AIDS Relief Program in South Africa: a modelling analysis. Open Forum Infectious Diseases 2025, 12: ofae631.010. PMCID: PMC11778235, DOI: 10.1093/ofid/ofae631.010.Peer-Reviewed Original ResearchHIV care cascadeHIV-related deathsCost-effectiveness of Preventing AIDS ComplicationsCare cascadeHIV infectionPEPFAR fundingHIV care continuum outcomesCare continuum outcomesHIV epidemic controlLife expectancyNew HIV infectionsGlobal health initiativesModified societal perspectiveLifetime costsSouth African adultsHealth initiativesHIV diagnosisHIV programsHIV statusPrimary preventionAIDS complicationsPWHPEPFARHIV budgetLife years
2018
The cost‐effectiveness and budgetary impact of a dolutegravir‐based regimen as first‐line treatment of HIV infection in India
Zheng A, Kumarasamy N, Huang M, Paltiel AD, Mayer KH, Rewari BB, Walensky RP, Freedberg KA. The cost‐effectiveness and budgetary impact of a dolutegravir‐based regimen as first‐line treatment of HIV infection in India. Journal Of The International AIDS Society 2018, 21: e25085. PMID: 29603882, PMCID: PMC5878415, DOI: 10.1002/jia2.25085.Peer-Reviewed Original ResearchConceptsIncremental cost-effectiveness ratioStandard of careAntiretroviral therapyTenofovir disoproxil fumarateHIV infectionRecent guidelinesFirst-line antiretroviral therapyFirst-line HIV treatmentLifetime incremental cost-effectiveness ratioART-naive patientsDolutegravir-based regimenDTG-based regimenFirst-line treatmentClinical trial dataCost-effectiveness ratioLifetime care costsInitial therapyVirologic suppressionCD4 countHIV diseaseRegimen costsDisoproxil fumarateHIV treatmentAIDS complicationsCare costs
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