2025
Short-term exposure to ambient nitrogen dioxide and fine particulate matter and cause-specific mortality: A causal modeling approach in four regions
Marb A, Ma Y, Nobile F, Dubrow R, Kinney P, Stafoggia M, Chen K, Peters A, Breitner S. Short-term exposure to ambient nitrogen dioxide and fine particulate matter and cause-specific mortality: A causal modeling approach in four regions. Environmental Pollution 2025, 372: 126059. PMID: 40089139, DOI: 10.1016/j.envpol.2025.126059.Peer-Reviewed Original ResearchParticulate matterAir pollutionDaily NO<sub>2</sub> anShort-term air pollution exposureNitrogen dioxideDaily air pollution dataExposure to NO<sub>2</sub>Effects of air pollutionShort-term exposure to NO<sub>2</sub> anFine particulate matterTwo-pollutant modelsExposure to ambient nitrogen dioxideAmbient air pollutionAmbient particulate matterAir pollution dataAir pollution exposureCause-specific mortality ratesAmbient nitrogen dioxideRural populationCause-specific mortalityRespiratory mortality ratesMortality rateCause-specific deathCardiovascular mortality ratesPollution exposureShort‐Term Associations Between Ambient Ozone and Acute Myocardial Infarction Onset Among Younger Patients: Results From the VIRGO Study
Zhang S, Chu L, Lu Y, Wei J, Dubrow R, Chaudhry S, Spatz E, Krumholz H, Chen K. Short‐Term Associations Between Ambient Ozone and Acute Myocardial Infarction Onset Among Younger Patients: Results From the VIRGO Study. GeoHealth 2025, 9: e2024gh001234. PMID: 39968338, PMCID: PMC11833228, DOI: 10.1029/2024gh001234.Peer-Reviewed Original ResearchAcute myocardial infarction subtypeShort-term associationsAcute myocardial infarctionAcute myocardial infarction onsetAMI riskEffect modificationAssociated with increased AMI riskParticipant's home addressNon-Hispanic blacksNon-ST-segment elevation acute myocardial infarctionNon-Hispanic whitesCase-crossover designType 1 AMIConditional logistic regressionIncreased AMI riskMyocardial infarction onsetType 2 AMIAcute myocardial infarction patientsST-segment elevation acute myocardial infarctionLifestyle factorsSociodemographic statusHome addressUS hospitalsStratified analysisSpatiotemporal deep learning approach
2024
Air pollution changes due to COVID-19 lockdowns and attributable mortality changes in four countries
Ma Y, Nobile F, Marb A, Dubrow R, Kinney P, Peters A, Stafoggia M, Breitner S, Chen K. Air pollution changes due to COVID-19 lockdowns and attributable mortality changes in four countries. Environment International 2024, 187: 108668. PMID: 38640613, DOI: 10.1016/j.envint.2024.108668.Peer-Reviewed Original ResearchConceptsMeteorological normalization techniqueAir pollution changesFine particulate matterImprove air qualityEmission control strategiesCentral-southern ItalyPollution changesParticulate matterRegion-specific estimatesAir qualityMeteorological impactsAir pollutionPollutionCOVID-19 lockdownModeling approachAirCaliforniaMortality changesConcentrationJiangsuEmissionTime trendsLocal characteristicsChinaMatterShort-Term Exposure to Fine Particulate Matter and Nitrogen Dioxide and Mortality in 4 Countries
Ma Y, Nobile F, Marb A, Dubrow R, Stafoggia M, Breitner S, Kinney P, Chen K. Short-Term Exposure to Fine Particulate Matter and Nitrogen Dioxide and Mortality in 4 Countries. JAMA Network Open 2024, 7: e2354607. PMID: 38427355, PMCID: PMC10907920, DOI: 10.1001/jamanetworkopen.2023.54607.Peer-Reviewed Original ResearchConceptsShort-term exposure to air pollutionExposure to air pollutionFine particulate matterCross-sectional studyAir pollutionFixed-effects modelParticulate matterShort-term exposure to PM2.5Short-term exposure to fine particulate matterNO2 concentrationsExposure to fine particulate matterMortality rateNitrogen dioxideSignificant effect modificationDaily PM2.5 concentrationsTime-varying confoundersExposure to PM2.5Health outcomesEstimate associationsMortality dataEffect modificationPM2.5 concentrationsMain OutcomesDay-to-dayCentral-southern ItalyA unified framework for assessing interaction effects among environmental exposures in epidemiologic studies: A case study on temperature, air pollution, and kidney-related conditions in New York state
Chu L, Chen K, Yang Z, Crowley S, Dubrow R. A unified framework for assessing interaction effects among environmental exposures in epidemiologic studies: A case study on temperature, air pollution, and kidney-related conditions in New York state. Environmental Research 2024, 248: 118324. PMID: 38301759, DOI: 10.1016/j.envres.2024.118324.Peer-Reviewed Original ResearchAir pollutionMultiplicative interaction effectsNew York StateEstimated health burdenCase-crossover designEvaluation of effect modificationBi-variate associationsAssess interaction effectsConditional logistic modelMeasures of exposureInteraction effectsEffect modificationPollutionExposure variablesHealth burdenEpidemiological studiesEnvironmental exposuresLog-linear modelLogistic modelInteraction termsQuantitative frameworkAirCase studyExposureAlert system
2023
Floods and Diarrhea Risk in Young Children in Low- and Middle-Income Countries
Wang P, Asare E, Pitzer V, Dubrow R, Chen K. Floods and Diarrhea Risk in Young Children in Low- and Middle-Income Countries. JAMA Pediatrics 2023, 177: 1206-1214. PMID: 37782513, PMCID: PMC10546297, DOI: 10.1001/jamapediatrics.2023.3964.Peer-Reviewed Original ResearchConceptsMiddle-income countriesDiarrhea riskOdds ratioMAIN OUTCOMEMixed-effects logistic regression modelRisk of diarrheaCross-sectional studyHigher odds ratioPrevalence of diarrheaLogistic regression modelsHealth survey programUnexposed childrenEffect modificationChild healthDiarrhea prevalenceSurvey clustersSignificant associationHygiene practicesFourth weekWeeksStrong associationRandom interceptYoung childrenChildrenDiarrheaAssociations between short-term exposure to PM2.5, NO2 and O3 pollution and kidney-related conditions and the role of temperature-adjustment specification: A case-crossover study in New York state
Chu L, Chen K, Di Q, Crowley S, Dubrow R. Associations between short-term exposure to PM2.5, NO2 and O3 pollution and kidney-related conditions and the role of temperature-adjustment specification: A case-crossover study in New York state. Environmental Pollution 2023, 328: 121629. PMID: 37054868, DOI: 10.1016/j.envpol.2023.121629.Peer-Reviewed Original ResearchAssociations between short-term temperature exposure and kidney-related conditions in New York State: The influence of temperature metrics across four dimensions
Chu L, Chen K, Crowley S, Dubrow R. Associations between short-term temperature exposure and kidney-related conditions in New York State: The influence of temperature metrics across four dimensions. Environment International 2023, 173: 107783. PMID: 36841184, DOI: 10.1016/j.envint.2023.107783.Peer-Reviewed Original Research
2022
Residential and Race/Ethnicity Disparities in Heat Vulnerability in the United States
Manware M, Dubrow R, Carrión D, Ma Y, Chen K. Residential and Race/Ethnicity Disparities in Heat Vulnerability in the United States. GeoHealth 2022, 6: e2022gh000695. PMID: 36518814, PMCID: PMC9744626, DOI: 10.1029/2022gh000695.Peer-Reviewed Original ResearchTriggering of myocardial infarction by heat exposure is modified by medication intake
Chen K, Dubrow R, Breitner S, Wolf K, Linseisen J, Schmitz T, Heier M, von Scheidt W, Kuch B, Meisinger C, Peters A, Schneider A. Triggering of myocardial infarction by heat exposure is modified by medication intake. Nature Cardiovascular Research 2022, 1: 727-731. PMID: 39196082, DOI: 10.1038/s44161-022-00102-z.Peer-Reviewed Original ResearchMyocardial infarctionEffect modificationMI riskPre-existing coronary heart diseaseAnti-platelet medicationCertain cardiovascular medicationsBeta-receptor blockersCoronary heart diseaseAcute myocardial infarctionHeat exposureCardiovascular medicationsOlder patientsYounger patientsMedication useMedication intakeHeart diseaseHigh prevalenceLow prevalenceMI casesMedicationsPatientsInfarctionSignificant differencesCHDPrevalenceAssociations between long-term drought and diarrhea among children under five in low- and middle-income countries
Wang P, Asare E, Pitzer VE, Dubrow R, Chen K. Associations between long-term drought and diarrhea among children under five in low- and middle-income countries. Nature Communications 2022, 13: 3661. PMID: 35773263, PMCID: PMC9247069, DOI: 10.1038/s41467-022-31291-7.Peer-Reviewed Original Research
2021
Predicting spatiotemporally-resolved air temperature over Sweden from satellite data using an ensemble model
Jin Z, Ma Y, Chu L, Liu Y, Dubrow R, Chen K. Predicting spatiotemporally-resolved air temperature over Sweden from satellite data using an ensemble model. ISEE Conference Abstracts 2021, 2021 DOI: 10.1289/isee.2021.o-to-189.Peer-Reviewed Original ResearchShort-term associations between ground-level ozone exposure and urinary system disease hospital admissions through the emergency room in Beijing, China
Chu L, Du H, Li T, Dubrow R, Chen K. Short-term associations between ground-level ozone exposure and urinary system disease hospital admissions through the emergency room in Beijing, China. ISEE Conference Abstracts 2021, 2021 DOI: 10.1289/isee.2021.p-120.Peer-Reviewed Original ResearchRole of meteorological factors in the transmission of SARS-CoV-2 in the United States
Ma Y, Pei S, Shaman J, Dubrow R, Chen K. Role of meteorological factors in the transmission of SARS-CoV-2 in the United States. ISEE Conference Abstracts 2021, 2021 DOI: 10.1289/isee.2021.p-599.Peer-Reviewed Original ResearchRole of meteorological factors in the transmission of SARS-CoV-2 in the United States
Ma Y, Pei S, Shaman J, Dubrow R, Chen K. Role of meteorological factors in the transmission of SARS-CoV-2 in the United States. Nature Communications 2021, 12: 3602. PMID: 34127665, PMCID: PMC8203661, DOI: 10.1038/s41467-021-23866-7.Peer-Reviewed Original Research
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