2025
Short‐Term Associations Between Ambient Ozone and Acute Myocardial Infarction Onset Among Younger Patients: Results From the VIRGO Study
Zhang S, Chu L, Lu Y, Wei J, Dubrow R, Chaudhry S, Spatz E, Krumholz H, Chen K. Short‐Term Associations Between Ambient Ozone and Acute Myocardial Infarction Onset Among Younger Patients: Results From the VIRGO Study. GeoHealth 2025, 9: e2024gh001234. PMID: 39968338, PMCID: PMC11833228, DOI: 10.1029/2024gh001234.Peer-Reviewed Original ResearchAcute myocardial infarction subtypeShort-term associationsAcute myocardial infarctionAcute myocardial infarction onsetAMI riskEffect modificationAssociated with increased AMI riskParticipant's home addressNon-Hispanic blacksNon-ST-segment elevation acute myocardial infarctionNon-Hispanic whitesCase-crossover designType 1 AMIConditional logistic regressionIncreased AMI riskMyocardial infarction onsetType 2 AMIAcute myocardial infarction patientsST-segment elevation acute myocardial infarctionLifestyle factorsSociodemographic statusHome addressUS hospitalsStratified analysisSpatiotemporal deep learning approach
2022
Triggering of myocardial infarction by heat exposure is modified by medication intake
Chen K, Dubrow R, Breitner S, Wolf K, Linseisen J, Schmitz T, Heier M, von Scheidt W, Kuch B, Meisinger C, Peters A, Schneider A. Triggering of myocardial infarction by heat exposure is modified by medication intake. Nature Cardiovascular Research 2022, 1: 727-731. PMID: 39196082, DOI: 10.1038/s44161-022-00102-z.Peer-Reviewed Original ResearchMyocardial infarctionEffect modificationMI riskPre-existing coronary heart diseaseAnti-platelet medicationCertain cardiovascular medicationsBeta-receptor blockersCoronary heart diseaseAcute myocardial infarctionHeat exposureCardiovascular medicationsOlder patientsYounger patientsMedication useMedication intakeHeart diseaseHigh prevalenceLow prevalenceMI casesMedicationsPatientsInfarctionSignificant differencesCHDPrevalence
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