Tuberculosis Transmission Between Residents and Migrants in Shanghai Revealed Through Genomic and Spatial Analysis
Tuberculosis, an infectious disease that is transmitted by coughing, is the leading cause of death attributable to a single pathogen. In China, which has the second highest number of tuberculosis cases in the world, massive rural-to-urban population shifts over the past 15 years have coincided with large increases of the disease in cities.
A Zika Vaccine Could Virtually Eliminate Prenatal Infections
A Zika vaccine could have a substantial effect on mitigating and preventing future Zika virus outbreaks. Through a combination of direct protection and indirect reduction of transmissions, virtual elimination is achievable, even with imperfect vaccine efficacy and coverage, a new Yale School of Public Health study finds.
Research in the news: Yale study pinpoints key genetic factor behind autoimmune diseases, cancer
Scientists have long known that variations in specific human genes are associated with distinct patterns of disease, but an understanding of the molecular mechanisms has remained elusive until now. A team of Yale researchers has untangled that mystery for a key immune response gene, a discovery which could lead to more personalized treatment for conditions such as lupus and cancer.
Fewer Doses of Antibody for Pneumonia, Bronchiolitis Possible, YSPH-led Study Finds
Respiratory Syncytial Virus, or RSV, is the most common cause of bronchiolitis and pneumonia in U.S. children under the age of one. While there is no current vaccine, children at high risk for RSV can receive a preventive therapy, consisting of five injections of an antibody to keep the virus at bay during the winter months, when epidemics are common.
How plants ward off a dangerous world of pathogens
The world’s plants, immobile and rooted in soil which contains potentially lethal micro-organisms, face a constant threat from invading pathogens. In recent years, however, scientists have discovered that plant species employ sophisticated immune strategies that differ from —but also shares similarities with — the ways humans combat infections.Source: Yale News
Gut check: Yale researchers describe role of bacteria in drug response
Yale researchers identified human gut microbes that metabolize over 150 therapeutic drugs, a finding that highlights the role bacteria play in determining how well individuals respond to medications, they report June 3 in the journal Nature.
Hinchcliff is New Director of Yale Scleroderma Program
Monique Hinchcliff, MD, MS, was named director of the Yale Scleroderma Program. Hinchcliff leads an established multidisciplinary team of expert physician-scientists with an interest and expertise in systemic sclerosis, also called scleroderma.