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Implementation Science and Outcomes Research

Only 14 percent of biomedical research is translated into practice, and among these there is a gap of about 17 years from the time a research article is submitted to eventual implementation. Many YPSH researchers work in implementation-science methods to close the gap between biomedical research and putting what is learned into practice.

Outcomes research seeks to understand the specific contribution of particular healthcare practices and interventions. It involves study design, critical review, implementation/measurement and analysis of health-outcomes studies. The scope of outcomes research ranges from studies evaluating the effectiveness of a particular intervention, to the development and use of tools to perform patient-based assessments, and to the impact of economic policies of the outcomes of care.

Outcomes- and implementation-science research address a number of chronic conditions, including heart disease, stroke, cancer and infectious-disease treatment such as respiratory, retroviral, enteric infections, helminth infections and vector-borne diseases.

Practice- and community-based research and initiatives

  • YSPH’s Center for Methods in Implementation Science and Prevention (CMIPS) aims to close implementation gaps through improving methods in practice, and works closely with the Center for Interdisciplinary Research on AIDS and global partners. In the fall of 2020, CMIPS was granted a NIH Implementation Science Consultation Hub Supplement to Support the Ending the HIV Epidemic Initiative.
  • GHLI builds capacity among individuals and teams to solve complex problems with measurable impact, catalyze innovation in global health, and work directly with Ministries of Health in mostly low- and middle-income countries to support their visions for strengthening health systems.
  • Work in Uganda informs national implementation guidelines on evidence-based TB interventions.
  • Other researchers are working with the Veterans Administration in West Haven, Connecticut, in implementation research aimed toward expanding access to chaplaincy services in outpatient clinics.