Nathaniel Rothman, MD, MPH

Molecular Epidemiology Studies of Occupational and Environmental Causes of Cancer

We are using biomarkers of exposure, early biologic effect, and genetic susceptibility to investigate the carcinogenic potential and mechanism of action of proven or suspected occupational and environmental compounds; to evaluate the influence of inter-individual variation in metabolism on the formation of important early biologic markers, such as DNA adducts and cytogenetic aberrations; and to assess the risk of premalignant conditions and cancer associated with exposure to occupational and environmental agents.