2025
Sex-biased Gene Expression Underlies Immune Dysfunction in Asthma.
Kay S, Rajeevan H, Son M, Kwah J, Ramirez M, Liu Y, Wang Z, Yan X, Nino G, Britto C, Chupp G, Gomez J. Sex-biased Gene Expression Underlies Immune Dysfunction in Asthma. American Journal Of Respiratory Cell And Molecular Biology 2025 PMID: 40587876, DOI: 10.1165/rcmb.2024-0565oc.Peer-Reviewed Original ResearchSex-biased gene expressionClinical featuresGene expressionType 2 inflammationClinical features of asthmaFeatures of asthmaAssociated with differential gene expressionExpression levelsImmune dysfunctionLocal validation cohortAdult patientsGene expression databaseValidation cohortImmune cellsClinical correlatesDifferential gene expressionGene expression differencesLymphocyte proliferationAllergic responsesAdult subjectsGene expression effectsGenetic polymorphismsImmune allergic responsesBlood samplesFemale genomes
2024
SDePER: a hybrid machine learning and regression method for cell-type deconvolution of spatial barcoding-based transcriptomic data
Liu Y, Li N, Qi J, Xu G, Zhao J, Wang N, Huang X, Jiang W, Wei H, Justet A, Adams T, Homer R, Amei A, Rosas I, Kaminski N, Wang Z, Yan X. SDePER: a hybrid machine learning and regression method for cell-type deconvolution of spatial barcoding-based transcriptomic data. Genome Biology 2024, 25: 271. PMID: 39402626, PMCID: PMC11475911, DOI: 10.1186/s13059-024-03416-2.Peer-Reviewed Original Research
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