Female aging: when translational models don’t translate
Gilmer G, Hettinger Z, Tuakli-Wosornu Y, Skidmore E, Silver J, Thurston R, Lowe D, Ambrosio F. Female aging: when translational models don’t translate. Nature Aging 2023, 3: 1500-1508. PMID: 38052933, PMCID: PMC11099540, DOI: 10.1038/s43587-023-00509-8.Peer-Reviewed Original ResearchConceptsAge-related diseasesBiology researchFrequent adverse eventsBiology researchersReproductive senescenceMechanistic understandingAdverse eventsMale patientsFemale patientsHigh morbidityPreclinical modelsPreclinical studiesPreclinical workSystemic effectsConsideration of sexTranslational modelPatientsPregnancyDiseaseSenescenceAging trajectoriesLong-term impactPhenotypeMorbidityBreastfeeding