Chlorinated paraffins in plasma of healthy elderly adults: Method development, temporal variability, and exposure determinants
Fang K, Guo X, He R, Sun Y, Huang Y, Cui H, Lu Y, Gu W, Wang C, Wan Y, Tang S, Shi X. Chlorinated paraffins in plasma of healthy elderly adults: Method development, temporal variability, and exposure determinants. Journal Of Hazardous Materials 2025, 495: 139065. PMID: 40580735, DOI: 10.1016/j.jhazmat.2025.139065.Peer-Reviewed Original ResearchMeSH KeywordsAgedEnvironmental ExposureEnvironmental MonitoringFemaleHumansHydrocarbons, ChlorinatedLimit of DetectionMaleMiddle AgedParaffinConceptsShort-chain chlorinated paraffinsMedium-chain chlorinated paraffinsLong-chain chlorinated paraffinsChlorinated paraffinsMethod quantification limitsHuman internal exposureMethod detection limitsGroup of persistent organic pollutantsLinear mixed-effects modelsTemporal variabilityPersistent organic pollutantsPrimary exposure pathwayCP exposureInternal exposureDietary pathwayExposure pathwaysPersistent pollutantsBiomonitoring samplesOrganic pollutantsVSCCPsExposure dynamicsDetection frequencyHealth risksShort-term variationsMixed-effects modelsAssociation between Organochlorine Exposures and Lung Functions Modified by Thyroid Hormones and Mediated by Inflammatory Factors among Healthy Older Adults
Guo X, Ren H, Zhang J, Ma X, Tong S, Tang S, Mao C, Shi X. Association between Organochlorine Exposures and Lung Functions Modified by Thyroid Hormones and Mediated by Inflammatory Factors among Healthy Older Adults. Biomedical And Environmental Sciences 2025, 38: 144-153. PMID: 40159168, DOI: 10.3967/bes2025.015.Peer-Reviewed Original ResearchConceptsLung functionInflammatory factorsIL-13Hormone groupThyroid hormonesEffects of IL-2Organochlorine exposureHealthy older adultsInterleukin (IL)-2Thyroid hormone levelsAssociated with forced vital capacityOlder adultsForced Vital CapacityIL-7IL-2Hormone levelsIL-8Wearable passive samplersEffects of organochlorinesAssociated with changesVital capacityLungMediation analysisParticipants' lung functionBlood samples
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