Urinary monohydroxylated polycyclic aromatic hydrocarbons among healthy elderly in the China BAPE study: Exposure characteristics, influencing factors, and health risks
Qian J, Guo X, Qi C, Sun P, Li C, Li C, Cao K, Xu Y, Ren H, Zhang J, Wang Y, Bao S, Qiu T, Wang C, Gu W, Lu Y, Tong S, Tang S, Shi X. Urinary monohydroxylated polycyclic aromatic hydrocarbons among healthy elderly in the China BAPE study: Exposure characteristics, influencing factors, and health risks. Journal Of Hazardous Materials 2025, 496: 139444. PMID: 40773834, DOI: 10.1016/j.jhazmat.2025.139444.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChinaEnvironmental ExposureEnvironmental PollutantsFemaleHumansMaleMiddle AgedPolycyclic Aromatic HydrocarbonsRisk AssessmentConceptsPolycyclic aromatic hydrocarbonsHealth risksHazard indexOH-PAHsPAH exposureUrinary OH-PAH concentrationsDietary exposure routeNon-carcinogenic riskPolycyclic aromatic hydrocarbon exposureOH-PAH concentrationsHuman health risksHealth risk assessmentRisk assessmentCarcinogenic risk assessmentConsumption of drinking waterAromatic hydrocarbonsExposure routesPartial burningMitigation policiesMixed-effects modeling techniquesDrinking waterComprehensive exposureCorn productionShandong ProvinceCarbon-based materialsAssociations between urinary polycyclic aromatic hydrocarbons and glycometabolic markers and potential mechanisms in healthy older adults: The China BAPE study
Li C, Fang J, Xu Y, Yang J, Ren H, Cao K, Ding E, Wang Y, Li C, Zhang J, Guo X, Qian J, Lu Y, Tong S, Tang S, Shi X. Associations between urinary polycyclic aromatic hydrocarbons and glycometabolic markers and potential mechanisms in healthy older adults: The China BAPE study. Journal Of Hazardous Materials 2025, 495: 139069. PMID: 40582155, DOI: 10.1016/j.jhazmat.2025.139069.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomarkersChinaEnvironmental ExposureEnvironmental PollutantsFemaleHumansMaleMetabolomicsMiddle AgedOxidative StressPolycyclic Aromatic HydrocarbonsConceptsUrinary PAH metabolitesMonthly follow-up visitsPolycyclic aromatic hydrocarbonsReactive oxygen speciesFollow-up visitPotential mechanismsType 2 diabetesPolycyclic aromatic hydrocarbon exposureUrine metabolomePAH metabolitesMetabolic healthMetabolic perturbationsMetabolic disordersAdverse outcome pathwayOlder adultsAromatic hydrocarbonsDiverse cohortPolycyclic aromatic hydrocarbon compoundsOxidative stressMarkersMolecular initiating eventUrinary polycyclic aromatic hydrocarbonsOxygen speciesMetabolitesAdults
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