2025
Urinary monohydroxylated polycyclic aromatic hydrocarbons among healthy elderly in the China BAPE study: Exposure characteristics, influencing factors, and health risks
Qian J, Guo X, Qi C, Sun P, Li C, Li C, Cao K, Xu Y, Ren H, Zhang J, Wang Y, Bao S, Qiu T, Wang C, Gu W, Lu Y, Tong S, Tang S, Shi X. Urinary monohydroxylated polycyclic aromatic hydrocarbons among healthy elderly in the China BAPE study: Exposure characteristics, influencing factors, and health risks. Journal Of Hazardous Materials 2025, 496: 139444. PMID: 40773834, DOI: 10.1016/j.jhazmat.2025.139444.Peer-Reviewed Original ResearchConceptsPolycyclic aromatic hydrocarbonsHealth risksHazard indexOH-PAHsPAH exposureUrinary OH-PAH concentrationsDietary exposure routeNon-carcinogenic riskPolycyclic aromatic hydrocarbon exposureOH-PAH concentrationsHuman health risksHealth risk assessmentRisk assessmentCarcinogenic risk assessmentConsumption of drinking waterAromatic hydrocarbonsExposure routesPartial burningMitigation policiesMixed-effects modeling techniquesDrinking waterComprehensive exposureCorn productionShandong ProvinceCarbon-based materialsAssociations between urinary polycyclic aromatic hydrocarbons and glycometabolic markers and potential mechanisms in healthy older adults: The China BAPE study
Li C, Fang J, Xu Y, Yang J, Ren H, Cao K, Ding E, Wang Y, Li C, Zhang J, Guo X, Qian J, Lu Y, Tong S, Tang S, Shi X. Associations between urinary polycyclic aromatic hydrocarbons and glycometabolic markers and potential mechanisms in healthy older adults: The China BAPE study. Journal Of Hazardous Materials 2025, 495: 139069. PMID: 40582155, DOI: 10.1016/j.jhazmat.2025.139069.Peer-Reviewed Original ResearchConceptsUrinary PAH metabolitesMonthly follow-up visitsPolycyclic aromatic hydrocarbonsReactive oxygen speciesFollow-up visitPotential mechanismsType 2 diabetesPolycyclic aromatic hydrocarbon exposureUrine metabolomePAH metabolitesMetabolic healthMetabolic perturbationsMetabolic disordersAdverse outcome pathwayOlder adultsAromatic hydrocarbonsDiverse cohortPolycyclic aromatic hydrocarbon compoundsOxidative stressMarkersMolecular initiating eventUrinary polycyclic aromatic hydrocarbonsOxygen speciesMetabolitesAdults
2024
Evaluation of various mass spectrometry mode based on gas chromatography for quantifying the polycyclic aromatic hydrocarbon metabolites in human urine
Bao S, Qian J, Qiu T, Jiang W, Gu W, Qu Y, Bai X, Yu X, Jiang Y, Tang S, Lv Y, Shi X, Lu Y. Evaluation of various mass spectrometry mode based on gas chromatography for quantifying the polycyclic aromatic hydrocarbon metabolites in human urine. Journal Of Chromatography A 2024, 1739: 465521. PMID: 39566290, DOI: 10.1016/j.chroma.2024.465521.Peer-Reviewed Original ResearchElectron ionizationHuman urinePolycyclic aromatic hydrocarbonsGas chromatographyOH-PAHsHydroxylated polycyclic aromatic hydrocarbonsTandem mass spectrometryRange of compoundsMethod validation criteriaMass spectrometry technologyAromatic hydrocarbonsMass spectrometryHuman exposure to polycyclic aromatic hydrocarbonsExposure to polycyclic aromatic hydrocarbonsPolycyclic aromatic hydrocarbon metabolitesNational human biomonitoring programSample volumeHuman biomonitoring programsHuman biological monitoringIonizationBiomonitoring programsUrine samplesHydrocarbon metabolitesBiological monitoringMinute concentrationsAssociation between exposure to chemical mixtures and epigenetic ageing biomarkers: Modifying effects of thyroid hormones and physical activity
Shi W, Fang J, Ren H, Sun P, Liu J, Deng F, Zhang S, Wang Q, Wang J, Tong S, Tang S, Shi X. Association between exposure to chemical mixtures and epigenetic ageing biomarkers: Modifying effects of thyroid hormones and physical activity. Journal Of Hazardous Materials 2024, 469: 134009. PMID: 38492399, DOI: 10.1016/j.jhazmat.2024.134009.Peer-Reviewed Original ResearchPolycyclic aromatic hydrocarbonsChemical mixture exposureOrganophosphate estersPolyfluoroalkyl substancesMixture exposurePhysical activityAir pollution exposureExposure to chemical mixturesEffects of environmental chemicalsLevels of physical activityAromatic hydrocarbonsPollution exposureHealthy ageing strategiesAged care policyChemical mixturesHealthy older adultsEnvironmental chemicalsEpigenetic ageing biomarkersAdverse effects of environmental chemicalsAcceleration of population agingLifestyle factorsCare policyOlder adultsHormone homeostasisPhthalate
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