2025
Chlorinated paraffins in plasma of healthy elderly adults: Method development, temporal variability, and exposure determinants
Fang K, Guo X, He R, Sun Y, Huang Y, Cui H, Lu Y, Gu W, Wang C, Wan Y, Tang S, Shi X. Chlorinated paraffins in plasma of healthy elderly adults: Method development, temporal variability, and exposure determinants. Journal Of Hazardous Materials 2025, 495: 139065. PMID: 40580735, DOI: 10.1016/j.jhazmat.2025.139065.Peer-Reviewed Original ResearchConceptsShort-chain chlorinated paraffinsMedium-chain chlorinated paraffinsLong-chain chlorinated paraffinsChlorinated paraffinsMethod quantification limitsHuman internal exposureMethod detection limitsGroup of persistent organic pollutantsLinear mixed-effects modelsTemporal variabilityPersistent organic pollutantsPrimary exposure pathwayCP exposureInternal exposureDietary pathwayExposure pathwaysPersistent pollutantsBiomonitoring samplesOrganic pollutantsVSCCPsExposure dynamicsDetection frequencyHealth risksShort-term variationsMixed-effects models
2024
Determination of persistent organochlorine pollutants in human serum by combining liquid-liquid extraction and solid-phase extraction with gas chromatography-tandem mass spectrometry
Qiu T, Jiang W, Bao S, Qian J, Wang C, Tang S, Shi X, Lu Y. Determination of persistent organochlorine pollutants in human serum by combining liquid-liquid extraction and solid-phase extraction with gas chromatography-tandem mass spectrometry. Microchemical Journal 2024, 197: 109699. DOI: 10.1016/j.microc.2023.109699.Peer-Reviewed Original ResearchSolid-phase extractionGas chromatography-tandem mass spectrometryLiquid-liquid extractionPersistent organochlorine pollutantsChromatography-tandem mass spectrometryMatrix effectsTarget analytesMass spectrometryMultiple reaction monitoring (MRM) modeReaction monitoring modeMethod detection limitsOrganochlorine pollutantsElectron impactSample preparation procedureGC-MS/MSDifferent spike levelsHuman serumApplicable analytical methodsLimit of quantificationMethyl tert-butyl etherQuality control samplesMonitoring modeTert-butyl etherDetection limitPreparation procedure
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