2025
Chlorinated paraffins in plasma of healthy elderly adults: Method development, temporal variability, and exposure determinants
Fang K, Guo X, He R, Sun Y, Huang Y, Cui H, Lu Y, Gu W, Wang C, Wan Y, Tang S, Shi X. Chlorinated paraffins in plasma of healthy elderly adults: Method development, temporal variability, and exposure determinants. Journal Of Hazardous Materials 2025, 495: 139065. PMID: 40580735, DOI: 10.1016/j.jhazmat.2025.139065.Peer-Reviewed Original ResearchConceptsShort-chain chlorinated paraffinsMedium-chain chlorinated paraffinsLong-chain chlorinated paraffinsChlorinated paraffinsMethod quantification limitsHuman internal exposureMethod detection limitsGroup of persistent organic pollutantsLinear mixed-effects modelsTemporal variabilityPersistent organic pollutantsPrimary exposure pathwayCP exposureInternal exposureDietary pathwayExposure pathwaysPersistent pollutantsBiomonitoring samplesOrganic pollutantsVSCCPsExposure dynamicsDetection frequencyHealth risksShort-term variationsMixed-effects modelsAir Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Zhu Q, Lyu Y, Huang K, Zhou J, Wang W, Steenland K, Chang H, Ebelt S, Shi X, Liu Y. Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS). GeoHealth 2025, 9: e2024gh001023. PMID: 39776607, PMCID: PMC11705411, DOI: 10.1029/2024gh001023.Peer-Reviewed Original ResearchChinese Longitudinal Health Longevity SurveyWarm-season O3Chinese elderly populationAssociated with cognitive impairmentLongevity SurveyCognitive impairmentLinear mixed-effects modelsChinese Longitudinal Healthy Longevity SurveyAir pollutionAssociation of air pollutionMixed-effects modelsAverage NO2Average PM2.5Elderly populationSingle-pollutant modelsMulti-pollutant modelsLogistic regression modelsCMMSE scoresControl Action PlanAir pollution preventionStudy participantsGaseous air pollutantsFollow-up visitRandom interceptPositive association
2024
Associations of environmental cadmium exposure with kidney damage: Exploring mediating DNA methylation sites in Chinese adults
Wei Y, Wang X, Sun Q, Shi W, Zhang W, Gao X, Li Y, Hao R, Dong X, Chen C, Cao K, Jiang W, Yang Z, Zhu Y, Lv Y, Xv D, Li J, Shi X. Associations of environmental cadmium exposure with kidney damage: Exploring mediating DNA methylation sites in Chinese adults. Environmental Research 2024, 251: 118667. PMID: 38462081, DOI: 10.1016/j.envres.2024.118667.Peer-Reviewed Original ResearchDifferentially methylated positionsUrinary CdDNA methylationAssociated with urinary CdSource of cadmiumExposure to CdEnvironmental Cd exposureNon-smoking adultsCd-induced kidney damageCd exposureEnvironmental CdDNA methylation sitesDNA methylation changesIllumina Infinium MethylationEPIC BeadChip arrayDNA methylation profilesEpigenome-wide associationInfinium MethylationEPIC BeadChip arrayLinear mixed-effects modelsMethylationEPIC BeadChip arrayEnvironmental pollutionPerspective of environmental pollutionMethylation sitesMethylation changesBeadChip arrayMethylation profiles
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