Association of Adiposity Markers, Serum 25-Hydroxyvitamin D, and Frailty in Older Adults: A Prospective Cohort Study
Wang X, Zhong W, Chen Z, Song W, You F, Li Z, Lv Y, Liu D, Shi X, Mao C. Association of Adiposity Markers, Serum 25-Hydroxyvitamin D, and Frailty in Older Adults: A Prospective Cohort Study. American Journal Of Clinical Nutrition 2025 PMID: 40876539, DOI: 10.1016/j.ajcnut.2025.08.013.Peer-Reviewed Original ResearchWeight-adjusted waist indexAssociated with frailty riskBody roundness indexAdiposity markersFrailty riskOlder adultsProspective cohort studyFrailty indexCohort studyHigh frailty riskSerum 25-hydroxyvitamin DWaist indexRoundness indexSerum 25(OH)DBody shape indexAssociation of adiposityFollow-upBody mass indexFrailty preventionJoint associationsWaist circumferenceBiomarkers Cohort StudyHealth deficitsLinear mixed modelsLow serum 25(OH)DThree-year lifestyle changes, genetic risk, and risk of frailty among older adults: A national community-based cohort study
Zhong W, Wang X, Song W, Chen H, Xie J, Yan H, Wang J, Lv Y, Li Z, Shi X, Mao C. Three-year lifestyle changes, genetic risk, and risk of frailty among older adults: A national community-based cohort study. Clinical Nutrition 2025, 50: 29-37. PMID: 40367593, DOI: 10.1016/j.clnu.2025.04.033.Peer-Reviewed Original ResearchConceptsRisk of frailtyGenetic riskHealthy lifestyleUnhealthy lifestyleOlder adultsFrailty riskLate-lifeLifestyle changesChinese Longitudinal Healthy Longevity SurveyCommunity-based cohort studyHazard ratioPolygenic risk scoresGenetic risk groupsModerate-to-moderatelyCox proportional hazards regression modelsProportional hazards regression modelsLifestyle scoreHazards regression modelsLongevity SurveyHigh frailty riskPrevent frailtyLifestyle factorsFrailty indexCohort studyLifestyle combinationAssociation of social relationships and genetic risk with frailty
Song W, Zhong W, Yan H, Li Z, Gao J, Wang X, Chen P, You F, Li C, Chen H, Xie J, Lv Y, Shi X, Mao C. Association of social relationships and genetic risk with frailty. American Journal Of Geriatric Psychiatry 2025 PMID: 40155233, DOI: 10.1016/j.jagp.2025.02.015.Peer-Reviewed Original ResearchPolygenic risk scoresFrailty riskGenetic riskMendelian randomizationOlder adultsChinese Longitudinal Healthy Longevity SurveyTwo-sample Mendelian randomizationAssociations of social relationshipsSocial relationshipsEffects of social relationshipsSocial activitiesCox proportional hazards modelsIncreased frailty riskLongevity SurveyHigh frailty riskProportional hazards modelUnfavorable relationshipSocial supportTwo-time pointsRisk scoreFrailtyHazards modelGenetic susceptibilityAdditive interactionSingle-nucleotide
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply