2025
Physical activities, longevity gene, and all-cause mortality among older adults: a prospective community-based cohort study
Xu L, Wang J, Li X, Li Y, Chen C, Xu Z, Xia Y, Lu Z, Zhou J, Zhang M, Wei Y, Wu B, Zhang Z, Li F, Luo Y, Chen G, Lv Y, Shi X. Physical activities, longevity gene, and all-cause mortality among older adults: a prospective community-based cohort study. BMC Medicine 2025, 23: 361. PMID: 40598362, PMCID: PMC12220457, DOI: 10.1186/s12916-025-04176-x.Peer-Reviewed Original ResearchConceptsPhysical activityRegular exerciseOlder adultsLeisure activitiesHealth benefits of physical activityBenefits of physical activityChinese Longitudinal Health Longevity SurveyProspective community-based cohort studyGenetic riskCommunity-based cohort studyHazard ratioChinese older adultsPhysical workFace-to-face interviewsHigh leisure activityAll-Cause MortalityPA recommendationsPA informationLongevity SurveyFace-to-faceMedian scoreCohort studyExerciseCox proportional risk modelHealth benefits
2024
Metabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study
Song W, Zhong W, Gao J, Li Z, Ren J, Shen D, Wang X, Shen Q, You F, Fu Q, Li C, Chen H, Lv Y, Shi X, Mao C. Metabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study. International Journal Of Obesity 2024, 48: 1438-1446. PMID: 38926462, DOI: 10.1038/s41366-024-01571-x.Peer-Reviewed Original ResearchMetabolically unhealthy non-obeseMetabolically healthy non-obeseMetabolically Healthy ObesityMetabolic obesity phenotypesOldest-old populationMetabolically unhealthy obesityProspective cohort studyMortality riskCohort studyHazard ratioObese phenotypeManagement of metabolic healthUnhealthy non-obeseOldest-old adultsHealthy non-obeseMethodsThis prospective cohort studyDecreased mortality riskIncreased mortality riskHigher mortality riskYears of follow-upAll-Cause MortalityNon-obeseEffect of obesityHealthy obesityCentral obesityAssociations of Low-density Lipoprotein Cholesterol With All-cause and Cause-specific Mortality in Older Adults in China
Ni W, Lv Y, Yuan X, Zhang Y, Zhang H, Zheng Y, Shi X, Xu J. Associations of Low-density Lipoprotein Cholesterol With All-cause and Cause-specific Mortality in Older Adults in China. The Journal Of Clinical Endocrinology & Metabolism 2024, 110: e132-e139. PMID: 38436437, DOI: 10.1210/clinem/dgae116.Peer-Reviewed Original ResearchCause-specific mortalityAssociation of low-density lipoprotein cholesterolAll-CauseOlder adultsLDL-C levelsLow-density lipoprotein cholesterolAssociated with increased cancer mortalityHazard ratioRisk of all-cause mortalityCVD-specific mortalityLDL-CMultivariable-adjusted HRCardiovascular diseaseProspective cohort studyLipoprotein cholesterolAll-Cause MortalityCox proportional hazards modelsOther-cause mortalityHealthy aging researchProportional hazards modelCancer mortalityVital statusMultivariate Cox proportional hazards modelLow LDL-C levelsMedian follow-up time
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