Association of Adiposity Markers, Serum 25-Hydroxyvitamin D, and Frailty in Older Adults: A Prospective Cohort Study
Wang X, Zhong W, Chen Z, Song W, You F, Li Z, Lv Y, Liu D, Shi X, Mao C. Association of Adiposity Markers, Serum 25-Hydroxyvitamin D, and Frailty in Older Adults: A Prospective Cohort Study. American Journal Of Clinical Nutrition 2025 PMID: 40876539, DOI: 10.1016/j.ajcnut.2025.08.013.Peer-Reviewed Original ResearchWeight-adjusted waist indexAssociated with frailty riskBody roundness indexAdiposity markersFrailty riskOlder adultsProspective cohort studyFrailty indexCohort studyHigh frailty riskSerum 25-hydroxyvitamin DWaist indexRoundness indexSerum 25(OH)DBody shape indexAssociation of adiposityFollow-upBody mass indexFrailty preventionJoint associationsWaist circumferenceBiomarkers Cohort StudyHealth deficitsLinear mixed modelsLow serum 25(OH)DThree-year lifestyle changes, genetic risk, and risk of frailty among older adults: A national community-based cohort study
Zhong W, Wang X, Song W, Chen H, Xie J, Yan H, Wang J, Lv Y, Li Z, Shi X, Mao C. Three-year lifestyle changes, genetic risk, and risk of frailty among older adults: A national community-based cohort study. Clinical Nutrition 2025, 50: 29-37. PMID: 40367593, DOI: 10.1016/j.clnu.2025.04.033.Peer-Reviewed Original ResearchConceptsRisk of frailtyGenetic riskHealthy lifestyleUnhealthy lifestyleOlder adultsFrailty riskLate-lifeLifestyle changesChinese Longitudinal Healthy Longevity SurveyCommunity-based cohort studyHazard ratioPolygenic risk scoresGenetic risk groupsModerate-to-moderatelyCox proportional hazards regression modelsProportional hazards regression modelsLifestyle scoreHazards regression modelsLongevity SurveyHigh frailty riskPrevent frailtyLifestyle factorsFrailty indexCohort studyLifestyle combination
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