2025
Associations between urinary polycyclic aromatic hydrocarbons and glycometabolic markers and potential mechanisms in healthy older adults: The China BAPE study
Li C, Fang J, Xu Y, Yang J, Ren H, Cao K, Ding E, Wang Y, Li C, Zhang J, Guo X, Qian J, Lu Y, Tong S, Tang S, Shi X. Associations between urinary polycyclic aromatic hydrocarbons and glycometabolic markers and potential mechanisms in healthy older adults: The China BAPE study. Journal Of Hazardous Materials 2025, 495: 139069. PMID: 40582155, DOI: 10.1016/j.jhazmat.2025.139069.Peer-Reviewed Original ResearchConceptsUrinary PAH metabolitesMonthly follow-up visitsPolycyclic aromatic hydrocarbonsReactive oxygen speciesFollow-up visitPotential mechanismsType 2 diabetesPolycyclic aromatic hydrocarbon exposureUrine metabolomePAH metabolitesMetabolic healthMetabolic perturbationsMetabolic disordersAdverse outcome pathwayOlder adultsAromatic hydrocarbonsDiverse cohortPolycyclic aromatic hydrocarbon compoundsOxidative stressMarkersMolecular initiating eventUrinary polycyclic aromatic hydrocarbonsOxygen speciesMetabolitesAdultsVegetarian diet and healthy aging among Chinese older adults: a prospective study
Jigeer G, Wang K, Lv Y, Tucker K, Shen X, Chen F, Sun L, Shi X, Li Y, Gao X. Vegetarian diet and healthy aging among Chinese older adults: a prospective study. Npj Aging 2025, 11: 25. PMID: 40169599, PMCID: PMC11961757, DOI: 10.1038/s41514-025-00213-4.Peer-Reviewed Original ResearchOlder adultsHealthy agingDiet qualityChinese Longitudinal Healthy Longevity SurveyHealth effects of vegetarian dietsOlder Chinese adultsNon-quantitative food frequency questionnaireChinese older adultsHigher diet qualityFood frequency questionnaireOverall health statusEffects of vegetarian dietsHealthy older adultsVegetarian dietLongevity SurveyLifestyle factorsFrequency questionnaireChinese adultsHealth componentDietary patternsHealth effectsAdultsMedian Follow-UpIndividual outcomesFollow-up
2024
Associations of Serum Per- and Polyfluoroalkyl Substances with Hyperuricemia in Adults: A Nationwide Cross-Sectional Study
Zheng X, Pan Y, Qu Y, Ji S, Wang J, Li Z, Zhao F, Wu B, Xie L, Li Y, Song H, Hu X, Qiu Y, Zhang Z, Zhang W, Yang Y, Cai J, Zhu Y, Zhu Y, Cao Z, Ji J, Lv Y, Dai J, Shi X. Associations of Serum Per- and Polyfluoroalkyl Substances with Hyperuricemia in Adults: A Nationwide Cross-Sectional Study. Environmental Science And Technology 2024, 58: 12875-12887. PMID: 38980177, DOI: 10.1021/acs.est.3c11095.Peer-Reviewed Original ResearchNationwide cross-sectional studyPublic health planningCross-sectional studyOdds of hyperuricemiaChinese adultsHealth plansJoint effectsElevated oddsGeneral populationNationwide studyNonmonotonic dose responsePositive associationRisk factorsAdultsHealthEffects of polyfluoroalkyl substancesHealth hazardsParticipantsSerum polyfluoroalkyl substancesJoint effects of PFAS mixtureMeasured serum concentrationsFish consumptionSerum concentrations of uric acidAssociationHyperuricemiaAnalysis of changes in social isolation, loneliness, or both, and subsequent cognitive function among older adults: Findings from a nationwide cohort study
Huang Q, Zhang P, Shen D, Gao J, Li Z, Lv Y, Shi X, Mao C. Analysis of changes in social isolation, loneliness, or both, and subsequent cognitive function among older adults: Findings from a nationwide cohort study. Alzheimer's & Dementia 2024, 20: 5674-5683. PMID: 38946708, PMCID: PMC11350036, DOI: 10.1002/alz.14080.Peer-Reviewed Original ResearchAssociated with accelerated cognitive declineCognitive impairment riskPersistent lonelinessSocial isolationCognitive declineOlder adultsImpairment riskChinese Longitudinal Healthy Longevity SurveyIncident cognitive impairmentCognitive impairmentAssociation of changesNationwide cohort studyAccelerated cognitive declineCognitive functionLongevity SurveyCohort studyChanging statusLonelinessRisk factorsRegression modelsTobit regression modelCox modelShort-termRiskAdults
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