2025
Acute endocrine disrupting effect of fine particulate constituents on thyroid homeostasis: A multicenter cross-sectional study in China
Tian Y, Chen C, Li J, Liu S, Fang J, Zhao F, Tang S, Zhang Y, Du P, Wang J, Zhang Z, Li Y, Ding E, Liu Y, Wang F, Shi W, Sun Q, Hu J, Shi X. Acute endocrine disrupting effect of fine particulate constituents on thyroid homeostasis: A multicenter cross-sectional study in China. Ecotoxicology And Environmental Safety 2025, 303: 118976. PMID: 40925186, DOI: 10.1016/j.ecoenv.2025.118976.Peer-Reviewed Original ResearchConceptsImpacts of PM2.5Endocrine disrupting effectsBeijing-Tianjin-HebeiHeavy metalsAmbient fine particulate matterFine particulate matterAir pollutant concentrationsAssociated with thyroid hormone levelsThyroid hormone homeostasisPollutant concentrationsIQR increaseParticulate matterMonitoring stationsConstituent concentrationsParticulate constituentsThyroid homeostasisPbSurrounding areaMultiple linear regression modelZnHormone homeostasisThyroid hormone levelsMetalAssociated with T3Cd
2024
Associations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study
Xing Y, Li Z, Wang J, Qu Y, Hu Q, Ji S, Chang X, Zhao F, Lv Y, Pan Y, Shi X, Dai J. Associations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study. Environment International 2024, 184: 108459. PMID: 38320373, DOI: 10.1016/j.envint.2024.108459.Peer-Reviewed Original ResearchConceptsRestricted cubic splinesBayesian kernel machine regressionNationally representative cross-sectional studyNonlinear dose-response associationDose-response associationChinese adult populationWeighted multiple linear regressionGeneral Chinese populationCross-sectional studyNationally representative dataYounger age groupsKernel machine regressionChinese adultsInverse associationG-computationPerfluoroheptane sulfonic acidQuantile-based g-computationAdult populationRepresentative dataSignificant associationPositive associationThyroid homeostasisChinese populationMultiple linear regressionAge groups
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