2025
Association of workforce participation with depression among US older adults: results from NHANES 2005–2018
Sun Z, Wang Y, Chen X, Qian D. Association of workforce participation with depression among US older adults: results from NHANES 2005–2018. BMC Geriatrics 2025, 25: 77. PMID: 39905307, PMCID: PMC11792604, DOI: 10.1186/s12877-025-05712-3.Peer-Reviewed Original ResearchConceptsNational Health and Nutrition Examination SurveyUS older adultsPHQ-9 scoresOlder adultsDepression riskLogistic regression modelsWorkforce participationPatient Health Questionnaire-9 itemsWork statusHealth and Nutrition Examination SurveyAnalysis of subgroupsRegular daytimeMethodsThis cross-sectional studyNutrition Examination SurveyPrevalence of depressionDecrease depression riskPotential reverse causationRegression modelsCross-sectional studyNon-linear associationInstrumental variablesPHQ-9Propensity score matchingExamination SurveyReverse causationExposure to School Racial Segregation and Late-Life Cognitive Outcomes
Lin Z, Wang Y, Gill T, Chen X. Exposure to School Racial Segregation and Late-Life Cognitive Outcomes. JAMA Network Open 2025, 8: e2452713. PMID: 39752159, PMCID: PMC11699536, DOI: 10.1001/jamanetworkopen.2024.52713.Peer-Reviewed Original ResearchConceptsCross-sectional studyCognitive scoresOlder adultsTelephone Interview for Cognitive StatusBlack participantsLate-life cognitive outcomesWhite participantsSchool racial segregationCognitive impairmentHealth and Retirement StudyNon-Hispanic whitePrevalence of cognitive impairmentAssociated with late-life cognitionEducational attainmentUS older adultsLikelihood of cognitive impairmentNon-Hispanic blacksLate-life cognitionCognitive outcomesNationally Representative SampleLater-life cognitionMultilevel regression analysisStudy of BlackDementia occurrenceHealth inequalities
2019
Associations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: Evidence from the Health and Retirement Study
Liu Z, Chen X, Gill TM, Ma C, Crimmins EM, Levine ME. Associations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: Evidence from the Health and Retirement Study. PLOS Medicine 2019, 16: e1002827. PMID: 31211779, PMCID: PMC6581243, DOI: 10.1371/journal.pmed.1002827.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseArtery diseasePhenotypic agingUS older adultsSelf-reported circumstancesRetirement StudyLife course circumstancesAssociation of geneticMorbidity riskMultivariable associationsPotential policy targetsRetrospective natureAdulthood circumstancesPhenotypic AgeAdulthood adversityGenetic predispositionHealth behaviorsSocioenvironmental circumstancesUS populationOlder adultsPotential interventionsDisadvantaged subpopulationsGenetic riskGenetic scoreUS Health
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