2021
Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis
Burry LD, Cheng W, Williamson DR, Adhikari NK, Egerod I, Kanji S, Martin CM, Hutton B, Rose L. Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis. Intensive Care Medicine 2021, 47: 943-960. PMID: 34379152, PMCID: PMC8356549, DOI: 10.1007/s00134-021-06490-3.Peer-Reviewed Original ResearchConceptsNon-pharmacological interventionsDelirium occurrenceIll adultsIll patientsInternational Clinical Trials RegistryDuration of deliriumOccurrence of deliriumMechanical ventilation durationMulti-component non-pharmacological interventionsClinical Trials RegistryLength of stayMulti-component interventionRandom-effects modelingEvidence networksWeb of ScienceEvidence certaintySedation interruptionSedative interruptionHospital lengthICU lengthCochrane riskSecondary outcomesStandard careBias toolControlled Trials
2020
Pharmacological prevention of fractures in patients undergoing glucocorticoid therapies: a systematic review and network meta-analysis
Deng J, Silver Z, Huang E, Zheng E, Kavanagh K, Wen A, Cheng W, Dobransky J, Sanger S, Grammatopoulos G. Pharmacological prevention of fractures in patients undergoing glucocorticoid therapies: a systematic review and network meta-analysis. Rheumatology 2020, 60: 649-657. PMID: 32572480, DOI: 10.1093/rheumatology/keaa228.Peer-Reviewed Original ResearchConceptsNon-vertebral fracturesDecreased oddsAdult patientsSystematic reviewNon-vertebral fracture incidenceAnti-fracture efficacyCochrane Central RegisterSystematic review registrationVitamin D metabolitesAllied Health LiteratureInternational Prospective RegisterWeb of ScienceGlucocorticoid therapyEligible patientsCentral RegisterControlled TrialsPharmacological preventionVertebral fracturesFracture incidenceReview registrationGC therapyVitamin D.D metabolitesProspective RegisterI2 statistic
2018
The efficacy and safety of topical tranexamic acid: A systematic review and meta-analysis
Montroy J, Hutton B, Moodley P, Fergusson NA, Cheng W, Tinmouth A, Lavallée LT, Fergusson DA, Breau RH. The efficacy and safety of topical tranexamic acid: A systematic review and meta-analysis. Transfusion Medicine Reviews 2018, 32: 165-178. PMID: 29567052, DOI: 10.1016/j.tmrv.2018.02.003.Peer-Reviewed Original ResearchTopical tranexamic acidTranexamic acidBlood lossIntravenous administrationTransfusion requirementsTopical applicationIntravenous tranexamic acidNon-surgical trialsVenous thromboembolic complicationsMean blood lossCochrane Central RegisterFull-text selectionMajority of trialsEffective hemostatic agentIntravenous groupThromboembolic riskVenous thromboembolismAdult patientsCentral RegisterThromboembolic complicationsBlood transfusionControlled TrialsTransfusion riskSafety profileSystemic absorption
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply