2025
Unraveling the role of viral interference in disrupting biennial RSV epidemics in northern Stockholm
Li K, Hamrin J, Nilsson A, Weinberger D, Pitzer V. Unraveling the role of viral interference in disrupting biennial RSV epidemics in northern Stockholm. Nature Communications 2025, 16: 8137. PMID: 40885786, PMCID: PMC12398580, DOI: 10.1038/s41467-025-63654-1.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusRespiratory syncytial virus activityViral interferenceH1N1 pandemic influenza virusPandemic H1N1 virusPandemic influenza virusNorthern StockholmBiennial patternH1N1 virusInfluenza virusIn vivo studiesRespiratory virusesSyncytial virusInfluenza pandemicRSV epidemicsBirth rateInfluenzaPublic health interventionsWinter outbreaksVirusAdmission dataH1N1InfantsOlder adultsHealth interventionsInterplay between the gut microbiome and typhoid fever: insights from endemic countries and a controlled human infection model
Ashton P, Mageiros L, Meiring J, Chunga-Chirambo A, Khanam F, Dongol S, Banda H, Karkey A, Preciado-Llanes L, Thomaides-Brears H, Gibani M, Rajib N, Rahman N, Biswas P, Bhuiyan M, Kay S, Auger K, Seret O, Thomson N, Pollard A, Baker S, Basnyat B, Clemens J, Dolecek C, Dunstan S, Dougan G, Heyderman R, Pitzer V, Qadri F, Gordon M, Holt K, Darton T. Interplay between the gut microbiome and typhoid fever: insights from endemic countries and a controlled human infection model. Microbiome 2025, 13: 168. PMID: 40696437, PMCID: PMC12281769, DOI: 10.1186/s40168-025-02125-7.Peer-Reviewed Original ResearchConceptsMetabolic gene clustersShort-chain fatty acidsTyphoid fever patientsS. typhiGut microbiomeTyphoid feverShort-chain fatty acid metabolismInfection modelAsymptomatic household contactsHuman infection modelPotential functional roleGene clusterShotgun metagenomicsInvasive SalmonellaFever patientsBacterial diversityMicrobiota characteristicsAssociated with typhoid feverBackgroundTyphoid feverStool microbiomeBacterial speciesClade ADevelopment of clinical infectionSCFA metabolismIngestion of contaminated food
2023
Typhoid fever
Meiring J, Khanam F, Basnyat B, Charles R, Crump J, Debellut F, Holt K, Kariuki S, Mugisha E, Neuzil K, Parry C, Pitzer V, Pollard A, Qadri F, Gordon M. Typhoid fever. Nature Reviews Disease Primers 2023, 9: 71. PMID: 38097589, DOI: 10.1038/s41572-023-00480-z.Peer-Reviewed Original ResearchConceptsTyphoid feverUndifferentiated febrile illnessInvasive bacterial diseaseEffective vaccination programsFecal-oral routeNovel diagnostic modalitiesFebrile illnessBloodstream infectionsVaccination programBlood culturesClinical trialsImmunological protectionHigh burdenCausative organismDiagnostic modalitiesGlobal burdenDisease pathogenesisFeverHuman infectionsIntestinal epitheliumYoung adultsCulture testingSalmonella enterica subspSerovar TyphiAntimicrobial resistance
2014
Predicting the Impact of Vaccination on the Transmission Dynamics of Typhoid in South Asia: A Mathematical Modeling Study
Pitzer VE, Bowles CC, Baker S, Kang G, Balaji V, Farrar JJ, Grenfell BT. Predicting the Impact of Vaccination on the Transmission Dynamics of Typhoid in South Asia: A Mathematical Modeling Study. PLOS Neglected Tropical Diseases 2014, 8: e2642. PMID: 24416466, PMCID: PMC3886927, DOI: 10.1371/journal.pntd.0002642.Peer-Reviewed Original ResearchConceptsChristian Medical College HospitalSubstantial indirect protectionMedical College HospitalCulture-confirmed casesImpact of vaccinationIncidence of typhoidTransmission dynamicsOne-time campaignChronic carriersCollege HospitalVaccination strategiesEndemic settingsTyphoid feverVaccinationTyphoid infectionTyphoid casesNatural historyIndirect protectionVi polysaccharideBasic reproductive numberTyphoidIncidenceTyphoid incidenceAge distributionReproductive number
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply