2025
Interplay between the gut microbiome and typhoid fever: insights from endemic countries and a controlled human infection model
Ashton P, Mageiros L, Meiring J, Chunga-Chirambo A, Khanam F, Dongol S, Banda H, Karkey A, Preciado-Llanes L, Thomaides-Brears H, Gibani M, Rajib N, Rahman N, Biswas P, Bhuiyan M, Kay S, Auger K, Seret O, Thomson N, Pollard A, Baker S, Basnyat B, Clemens J, Dolecek C, Dunstan S, Dougan G, Heyderman R, Pitzer V, Qadri F, Gordon M, Holt K, Darton T. Interplay between the gut microbiome and typhoid fever: insights from endemic countries and a controlled human infection model. Microbiome 2025, 13: 168. PMID: 40696437, PMCID: PMC12281769, DOI: 10.1186/s40168-025-02125-7.Peer-Reviewed Original ResearchConceptsMetabolic gene clustersShort-chain fatty acidsTyphoid fever patientsS. typhiGut microbiomeTyphoid feverShort-chain fatty acid metabolismInfection modelAsymptomatic household contactsHuman infection modelPotential functional roleGene clusterShotgun metagenomicsInvasive SalmonellaFever patientsBacterial diversityMicrobiota characteristicsAssociated with typhoid feverBackgroundTyphoid feverStool microbiomeBacterial speciesClade ADevelopment of clinical infectionSCFA metabolismIngestion of contaminated food
2023
Year-Round Respiratory Syncytial Virus Transmission in The Netherlands Following the COVID-19 Pandemic: A Prospective Nationwide Observational and Modeling Study
Löwensteyn Y, Zheng Z, Rave N, Bannier M, Billard M, Casalegno J, Pitzer V, Wildenbeest J, Weinberger D, Bont L, Putten M, Smit-Kleinlugtenbeld E, Peetsold M, van der Kuip M, van Goudoever H, van Keulen B, Boot A, Kloos R, van Gool S, Snepvangers Y, Kuijpers A, Menelik N, de Crom S, Miedema C, Tusscher G, van Giessen J, de Moor R, Faber M, Breukels M, Jaddoe V, Duijts L, Lutterman C, Vink I, Tramper-Stranders G, Oudshoorn A, Ritman A, Dubbink-Verheij G, Bolt J, Cakir C, Rietveld E, Bekhof J, Rings E, de Swart J, Driessen G, Doedens R, Nijssen L, van Onzenoort-Bokken L, Meijneke R, van Scherpenzeel M, Faber T, de Groof F, Schouten S, van de Zande J, de Coul M, Henriet S, Stol K, van Rossem M, Jacobs M, van Houten M, Zuurbier R, Plötz F, de Vries A, van der Heide R, van Boekholt A, de Jong G, Rashid A, Roelofs M, Illy K, Reijmerink N, van Dorth S, Schipper S, Rosias P, Teirlinck A. Year-Round Respiratory Syncytial Virus Transmission in The Netherlands Following the COVID-19 Pandemic: A Prospective Nationwide Observational and Modeling Study. The Journal Of Infectious Diseases 2023, 228: 1394-1399. PMID: 37477906, PMCID: PMC10640768, DOI: 10.1093/infdis/jiad282.Peer-Reviewed Original ResearchMeSH KeywordsChildCOVID-19HumansNetherlandsPandemicsProspective StudiesRespiratory Syncytial Virus InfectionsRespiratory Syncytial Virus, HumanSeasons
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