Genetically proxied tumour necrosis factor inhibition and pregnancy-related maternal and foetal outcomes in the general population: a Mendelian randomization study
Zhao S, Woolf B, Rogne T, Gill D. Genetically proxied tumour necrosis factor inhibition and pregnancy-related maternal and foetal outcomes in the general population: a Mendelian randomization study. Rheumatology Advances In Practice 2025, 9: rkaf100. PMID: 40937292, PMCID: PMC12422557, DOI: 10.1093/rap/rkaf100.Peer-Reviewed Original ResearchPregnancy-related outcomesRisk of gestational diabetesTNF inhibitorsGestational diabetesAssociated with lower riskFoetal outcomesPre-eclampsiaPreterm birthSpontaneous abortionHyperemesis gravidarumPregnancy-relatedLow risk of gestational diabetesOutcome of spontaneous abortionRate of preterm deliverySafety of TNF inhibitorsTumor necrosis factor inhibitionAdverse pregnancy-related outcomesAt-risk pregnant womenAssociated with CRPPreterm deliveryEctopic pregnancyGenetic confoundingPregnant womenRandomized studyFactor inhibition
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