2025
Symptom trajectories after COVID hospitalization and risk factors for symptom burden in older persons: a longitudinal cohort study
Pan Y, Cho G, Geda M, Gill T, Cohen A, Ferrante L, Hajduk A, Miner B. Symptom trajectories after COVID hospitalization and risk factors for symptom burden in older persons: a longitudinal cohort study. The Journals Of Gerontology Series A 2025, 80: glaf132. PMID: 40512177, PMCID: PMC12351543, DOI: 10.1093/gerona/glaf132.Peer-Reviewed Original ResearchHigh symptom burdenAssociated with high symptom burdenSymptom burdenGeriatric conditionsPsychosocial factorsOlder personsOlder adultsEdmonton Symptom Assessment SystemCommunity-dwelling older adultsSymptom trajectoriesModified Edmonton Symptom Assessment SystemYale New Haven Health SystemPost-COVID symptomsEvaluate symptom burdenImpairment of physical functionFemale sexMonths post-dischargeRisk factorsLongitudinal cohort studyMultinomial logistic regressionIdentified risk factorsPhysical functionHealth systemSocial supportPost-dischargeIncidence of Frailty, Dementia, and Disability Among Community‐Living Older Americans According to County‐Level Disadvantage
Wang Y, Zang E, Davis‐Plourde K, Vander Wyk B, Gill T, Becher R. Incidence of Frailty, Dementia, and Disability Among Community‐Living Older Americans According to County‐Level Disadvantage. Journal Of The American Geriatrics Society 2025, 73: 1847-1856. PMID: 40196885, PMCID: PMC12213133, DOI: 10.1111/jgs.19465.Peer-Reviewed Original ResearchConceptsNational Health and Aging Trends StudyActivities of daily living disabilityActivities of daily livingIncidence of frailtySocial determinants of healthOlder personsOlder AmericansContextual disadvantageAge- and sex-adjusted HRDisadvantaged countiesDeterminants of healthSex-adjusted HRNationally representative longitudinal studyRepresentative longitudinal studyCommunity-livingDaily livingClinically Meaningful OutcomesTrends StudyGeriatric conditionsNo prior studiesNational incidenceIncidence rateDementiaFrailtyCounty-levelCritical Illness, Major Surgery, and Other Hospitalizations and Active and Disabled Life Expectancy
Gill T, Zang E, Leo-Summers L, Gahbauer E, Becher R, Ferrante L, Han L. Critical Illness, Major Surgery, and Other Hospitalizations and Active and Disabled Life Expectancy. JAMA Network Open 2025, 8: e254208. PMID: 40178853, PMCID: PMC11969285, DOI: 10.1001/jamanetworkopen.2025.4208.Peer-Reviewed Original ResearchConceptsActive life expectancyDisabled life expectancyCommunity-living older personsActivities of daily livingFunctional well-beingOlder personsLife expectancyDaily livingEssential activities of daily livingEstimates of active life expectancySurgical admissionsCommunity-living personsCritical illnessMultistate life tablesElective surgical admissionsWell-being of older personsProspective cohort studyMain OutcomesCohort studyWell-beingIllnessLife tablesAge incrementElective surgical proceduresHospitalExtreme Heat and Hospitalization Among Older Persons With Alzheimer Disease and Related Dementias
Delaney S, Stegmuller A, Mork D, Mock L, Bell M, Gill T, Braun D, Zanobetti A. Extreme Heat and Hospitalization Among Older Persons With Alzheimer Disease and Related Dementias. JAMA Internal Medicine 2025, 185: 412-421. PMID: 39899291, PMCID: PMC11791774, DOI: 10.1001/jamainternmed.2024.7719.Peer-Reviewed Original ResearchCase-crossover designOdds ratioPopulation-based cohort studyMedicare fee-for-serviceBurden of Alzheimer's diseaseConditional logistic regressionFee-for-serviceOR point estimatesRisk of hospitalizationADRDOlder personsOlder adultsMain OutcomesPopulation subgroupsWhite beneficiariesDiagnosis codesCohort studyEffect estimatesHealth burdenLogistic regressionCounseling patientsCumulative ORAlzheimer's diseaseIncreased hospitalizationOutdoor heatNovel indices of state- and county-level social disadvantage in older Americans and disparities in mortality
Wang Y, Zang E, Davis-Plourde K, Gill T, Becher R. Novel indices of state- and county-level social disadvantage in older Americans and disparities in mortality. Health & Place 2025, 92: 103438. PMID: 40058245, PMCID: PMC12142587, DOI: 10.1016/j.healthplace.2025.103438.Peer-Reviewed Original ResearchConceptsIncreased mortality riskContextual disadvantageOlder personsOlder AmericansCommunity-living older personsSocial disadvantageMortality riskIndices of social disadvantageReduce health disparitiesPopulation of older AmericansCounty-levelPublic health policiesNon-disadvantaged groupsMortality disparitiesHealth disparitiesHealth policyMortality existUnited StatesDisadvantaged countiesNegative binomial modelGeriatric populationComposite indexDisparitiesDisadvantaged statesMultidimensional factorsIncomplete Ascertainment of Mortality in a Nationally Representative Longitudinal Study of Community-Living Older Americans
Gill T, Liang J, Vander Wyk B, Leo-Summers L, Wang Y, Becher R, Davis-Plourde K. Incomplete Ascertainment of Mortality in a Nationally Representative Longitudinal Study of Community-Living Older Americans. The Journals Of Gerontology Series A 2025, 80: glaf014. PMID: 39823281, PMCID: PMC12269764, DOI: 10.1093/gerona/glaf014.Peer-Reviewed Original ResearchNational Health and Aging Trends StudyAscertainment of mortalityIncomplete ascertainmentLongitudinal studies of older personsStudy of older personsNationally representative longitudinal studyIncidence rate ratiosLoss to follow-upMortality incidence ratesYear of deathLongitudinal studyRepresentative longitudinal studyCommunity-livingTrends StudyOlder personsRecommended strategiesMedicare dataRate ratiosCumulative mortality rateIncidence rateResults of longitudinal analysesAscertainmentEvaluate mortalityLongitudinal analysisDecedents
2024
Gender differences in the associations of circadian function with cognition among older persons with sleep disturbances
Pan Y, Cho G, Doyle M, Polisetty L, Burzynski C, Iannone L, Knauert M, Yaggi H, Gill T, Miner B. Gender differences in the associations of circadian function with cognition among older persons with sleep disturbances. Alzheimer's & Dementia 2024, 20: e089617. PMCID: PMC11716249, DOI: 10.1002/alz.089617.Peer-Reviewed Original ResearchMoCA scoresOlder adultsCognitive functionCommunity-dwelling older adultsCommunity-living adultsSleep disturbanceMontreal Cognitive AssessmentNo significant associationSleep-related factorsDays of actigraphyOlder personsActivity countsGender differencesPearson correlation coefficientMinority raceScore associationsInvestigate gender differencesCognitive AssessmentCircadian functionSlow wave sleepSignificant associationTotal sleep timeMoCANight of polysomnographyOlder menChanges in neighborhood disadvantage over the course of 22 years among community‐living older persons
Gill T, Becher R, Leo‐Summers L, Gahbauer E. Changes in neighborhood disadvantage over the course of 22 years among community‐living older persons. Journal Of The American Geriatrics Society 2024, 73: 199-205. PMID: 39206716, PMCID: PMC11735297, DOI: 10.1111/jgs.19172.Peer-Reviewed Original ResearchArea Deprivation IndexArea deprivation index scoreNeighborhood disadvantageDisadvantaged neighborhoodsOlder personsLongitudinal studies of older personsCommunity-living older personsSocial determinants of healthStudy of older personsCommunity-living personsDeterminants of healthFunctional well-beingCensus block levelSouth central ConnecticutDeprivation indexSocial determinantsFollow-upProspective longitudinal studyWell-beingLongitudinal studyDecile changeCentral ConnecticutNeighborhoodParticipantsPersons0309 Concordance in Electroencephalography-Headband versus Polysomnography by Demographics and Cognitive Status
Miner B, Pan Y, Cho G, Burzynski C, Polisetty L, Doyle M, Iannone L, Knauert M, Gill T, Yaggi H. 0309 Concordance in Electroencephalography-Headband versus Polysomnography by Demographics and Cognitive Status. Sleep 2024, 47: a133-a133. DOI: 10.1093/sleep/zsae067.0309.Peer-Reviewed Original ResearchTotal sleep timeIntraclass correlation coefficientMeasure total sleep timeMild cognitive impairmentCognitive statusSleep complaintsNight of home-based polysomnographyHome-based polysomnographySelf-reported sleep complaintsCommunity-living older adultsBetween-group differencesPaired t-testPresence of mild cognitive impairmentExcellent concordanceSleep timeAcceptable alternativeWASOPolysomnographyReduced concordancePSGSleep disturbanceOlder personsOlder adultsPeople of colorWomen0757 Association of Insomnia with Objective Short Sleep Duration and Other Phenotypes with Mortality in Older Persons
Miner B, Pan Y, Cho G, Knauert M, Yaggi H, Gill T, Stone K, Ensrud K, Zeitzer J, Yaffe K, Doyle M. 0757 Association of Insomnia with Objective Short Sleep Duration and Other Phenotypes with Mortality in Older Persons. Sleep 2024, 47: a324-a325. DOI: 10.1093/sleep/zsae067.0757.Peer-Reviewed Original ResearchAssociated with increased mortality riskAssociation of insomniaMortality riskOlder personsShort sleep durationOsteoporotic fracturesAdjusted modelsStudy of Osteoporotic FracturesSleep durationHigher mortality riskCox proportional hazards modelsMen Sleep StudyNormal sleepProportional hazards modelAssociated with mortalitySevere sleep-disordered breathingUnadjusted modelsUnadjusted analysisCausal pathwaysSleep-disordered breathingFollow-up timePrevalence ratesReference groupHazards modelRisk phenotypesNational Estimates of Short- and Longer-Term Hospital Readmissions After Major Surgery Among Community-Living Older Adults
Wang Y, Leo-Summers L, Vander Wyk B, Davis-Plourde K, Gill T, Becher R. National Estimates of Short- and Longer-Term Hospital Readmissions After Major Surgery Among Community-Living Older Adults. JAMA Network Open 2024, 7: e240028. PMID: 38416499, PMCID: PMC10902728, DOI: 10.1001/jamanetworkopen.2024.0028.Peer-Reviewed Original ResearchConceptsCenters for Medicare & Medicaid ServicesFee-for-serviceMedicare Advantage beneficiariesHospital readmissionUS residentsNational Health and Aging Trends Study dataCommunity-living older adultsProspective longitudinal cohort studyCommunity-living participantsRate of hospital readmissionLikelihood of hospital readmissionPopulation-based estimatesNationally representative estimatesSex-adjusted modelsCommunity-livingData linkageGeriatric conditionsMedicaid ServicesOlder personsOlder adultsMain OutcomesNational estimatesRepresentative estimatesData analysisCohort study
2023
Relationship Between Distressing Symptoms and Changes in Disability After Major Surgery Among Community-living Older Persons
Gill T, Han L, Feder S, Gahbauer E, Leo-Summers L, Becher R. Relationship Between Distressing Symptoms and Changes in Disability After Major Surgery Among Community-living Older Persons. Annals Of Surgery 2023, 279: 65-70. PMID: 37389893, PMCID: PMC10761592, DOI: 10.1097/sla.0000000000005984.Peer-Reviewed Original ResearchConceptsMajor surgeryDistressing symptomsElective surgeryFunctional outcomeOlder personsCommunity-living older personsMultiple distressing symptomsSocioeconomic disadvantageCommunity-living personsTiming of surgerySerious health eventsNumber of disabilitiesSurgerySignificant associationSymptomsHealth eventsRate ratioPotential targetDisabilityUnit increaseDeleterious effectsOutcomesPersonsMultimorbidityAdmissionDistressing symptoms after major surgery among community‐living older persons
Gill T, Han L, Murphy T, Feder S, Gahbauer E, Leo‐Summers L, Becher R. Distressing symptoms after major surgery among community‐living older persons. Journal Of The American Geriatrics Society 2023, 71: 2430-2440. PMID: 37010784, PMCID: PMC10524276, DOI: 10.1111/jgs.18357.Peer-Reviewed Original ResearchConceptsCommunity-living older personsMajor surgeryDistressing symptomsArea Deprivation IndexOlder personsSocioeconomic disadvantageCommunity-living personsTiming of surgeryProspective longitudinal studyYears of ageQuality of lifeSymptom burdenNonelective surgeryPresurgery valuesElective surgeryMultivariable analysisFunctional outcomeNonelective proceduresChronic conditionsSurgerySymptomsProportional increaseMedicaid eligibilityDeprivation indexMonths
2022
2022 IRVING S. WRIGHT AWARD
Gill T. 2022 IRVING S. WRIGHT AWARD. Innovation In Aging 2022, 6: 162-162. PMCID: PMC9765735, DOI: 10.1093/geroni/igac059.648.Peer-Reviewed Original ResearchClaude D. Pepper Older Americans Independence CenterOlder personsCommunity-living older personsPrevention of disabilityMultisite clinical trialProfessor of EpidemiologyClinical trialsDisabling disorderClinical epidemiologyFunctional declineEpidemiologyMechanisms underlyingNational InstituteInvestigative medicineDisabilityOriginal reportTraining programMedicinePersonsTrialsPreventionInsomnia with objective short sleep duration in community‐living older persons: A multifactorial geriatric health condition
Miner B, Doyle M, Knauert M, Yaggi H, Stone K, Ancoli‐Israel S, Cauley J, Redline S, Blackwell T, Gill T, Groups F. Insomnia with objective short sleep duration in community‐living older persons: A multifactorial geriatric health condition. Journal Of The American Geriatrics Society 2022, 71: 1198-1208. PMID: 36524599, PMCID: PMC10089942, DOI: 10.1111/jgs.18195.Peer-Reviewed Original ResearchConceptsShort sleep durationObjective short sleep durationCommunity-living older personsSleep durationOsteoporotic fracturesOlder menCommunity-living older menOlder personsMultiple predisposingHealth conditionsMen Sleep StudyModifiable risk factorsSeparate logistic regression modelsPoor sleep qualityHigh-risk phenotypeCross-sectional studyCross-sectional associationsMiddle-aged personsLogistic regression modelsClinical correlatesRisk factorsMultivariable modelSleep studiesSleep qualityOlder womenFactors Associated With Days Away From Home in the Year After Major Surgery Among Community-living Older Persons
Gill TM, Becher RD, Murphy TE, Gahbauer EA, Leo-Summers L, Han L. Factors Associated With Days Away From Home in the Year After Major Surgery Among Community-living Older Persons. Annals Of Surgery 2022, 278: e13-e19. PMID: 35837967, PMCID: PMC9840715, DOI: 10.1097/sla.0000000000005528.Peer-Reviewed Original ResearchConceptsHealth care facilitiesMajor surgeryAge 85 yearsCare facilitiesOlder personsRisk factorsNumber of daysLower peak expiratory flowCommunity-living older personsShort Physical Performance BatteryIndependent risk factorCommunity-living personsPhysical Performance BatteryPeak expiratory flowCandidate risk factorsQuality of lifeHospital dischargeMultivariable analysisExpiratory flowMedian numberPerformance BatteryMusculoskeletal surgerySurgeryMean differenceHospital0321 Poor Agreement Among Self-Reported and Objective Sleep Deficiency Assessments in Older Persons
Miner B, Yaggi H, Gill T, Doyle M, Stone K, Redline S, Ensrud K, Blackwell T, Knauert M. 0321 Poor Agreement Among Self-Reported and Objective Sleep Deficiency Assessments in Older Persons. Sleep 2022, 45: a144-a145. DOI: 10.1093/sleep/zsac079.319.Peer-Reviewed Original ResearchInsufficient sleep durationSleep QuestionnaireSleep deficiencySleep durationAttention/alertnessOsteoporotic fracturesClaude D. Pepper Older Americans Independence CenterOlder personsNormal scoresSleep-disordered breathingAge-related decreaseAtypical presentationAverage ageNormal rangeSymptom awarenessOlder menSleep deficitsAmerican AcademySecondary analysisYoung populationSubstantial proportionNational InstituteWomenMenPoor sensitivity
2021
Association Between Neighborhood Disadvantage and Functional Well-being in Community-Living Older Persons
Gill TM, Zang EX, Murphy TE, Leo-Summers L, Gahbauer EA, Festa N, Falvey JR, Han L. Association Between Neighborhood Disadvantage and Functional Well-being in Community-Living Older Persons. JAMA Internal Medicine 2021, 181: 1297-1304. PMID: 34424276, PMCID: PMC8383163, DOI: 10.1001/jamainternmed.2021.4260.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedFemaleFunctional StatusHealthy Life ExpectancyHousing QualityHumansIndependent LivingLongitudinal StudiesMaleMental HealthNeighborhood CharacteristicsPrognosisPsychosocial FunctioningQuality of LifeSocial Determinants of HealthSocioeconomic FactorsUnited StatesConceptsProspective longitudinal cohort studyCommunity-living older personsAge 70 yearsActive life expectancyLongitudinal cohort studyOlder personsCohort studyPrognostic factorsLife expectancyArea deprivation index scoreCommunity-living personsPrecipitating Events ProjectDeprivation index scoreDisabled life expectancyAge 90 yearsArea Deprivation IndexPublic health initiativesPublic health interventionsNeighborhood disadvantageGreater percentageResource-poor environmentsIndividual-level socioeconomic characteristicsMean ageMAIN OUTCOMEDaily livingThe Incidence and Cumulative Risk of Major Surgery in Older Persons in the United States
Becher RD, Vander Wyk B, Leo-Summers L, Desai MM, Gill TM. The Incidence and Cumulative Risk of Major Surgery in Older Persons in the United States. Annals Of Surgery 2021, 277: 87-92. PMID: 34261884, PMCID: PMC8758792, DOI: 10.1097/sla.0000000000005077.Peer-Reviewed Original ResearchConceptsMajor surgeryOlder personsCumulative riskNational HealthCommunity-living older personsHigh-quality surgical careNon-frail groupPopulation-based incidenceService Medicare beneficiariesMedicaid Services dataCumulative risk estimatesProspective longitudinal studyUnited States agesAging Trends StudyGeriatric characteristicsRepresentative incidenceFrail groupAdjusted incidenceGeriatric populationProbable dementiaSurgical carePersons 85Medicare beneficiariesSurgeryVulnerable subgroups
2020
Functional Effects of Intervening Illnesses and Injuries After Hospitalization for Major Surgery in Community-living Older Persons
Gill TM, Han L, Gahbauer EA, Leo-Summers L, Murphy TE, Becher RD. Functional Effects of Intervening Illnesses and Injuries After Hospitalization for Major Surgery in Community-living Older Persons. Annals Of Surgery 2020, 273: 834-841. PMID: 33074902, PMCID: PMC8370041, DOI: 10.1097/sla.0000000000004438.Peer-Reviewed Original ResearchConceptsMajor surgeryED visitsRestricted activityFunctional statusFunctional declineOlder personsCommunity-living older personsAdjusted hazard ratioAdverse functional outcomesCommunity-living personsEmergency department visitsTraditional risk factorsCorresponding odds ratiosFunctional effectsIllness/injuryHazard ratioDepartment visitsFunctional recoveryFunctional outcomeRisk factorsOdds ratioHospitalizationSurgeryInjuryVisits
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