2025
Symptom trajectories after COVID hospitalization and risk factors for symptom burden in older persons: a longitudinal cohort study
Pan Y, Cho G, Geda M, Gill T, Cohen A, Ferrante L, Hajduk A, Miner B. Symptom trajectories after COVID hospitalization and risk factors for symptom burden in older persons: a longitudinal cohort study. The Journals Of Gerontology Series A 2025, 80: glaf132. PMID: 40512177, PMCID: PMC12351543, DOI: 10.1093/gerona/glaf132.Peer-Reviewed Original ResearchHigh symptom burdenAssociated with high symptom burdenSymptom burdenGeriatric conditionsPsychosocial factorsOlder personsOlder adultsEdmonton Symptom Assessment SystemCommunity-dwelling older adultsSymptom trajectoriesModified Edmonton Symptom Assessment SystemYale New Haven Health SystemPost-COVID symptomsEvaluate symptom burdenImpairment of physical functionFemale sexMonths post-dischargeRisk factorsLongitudinal cohort studyMultinomial logistic regressionIdentified risk factorsPhysical functionHealth systemSocial supportPost-dischargeAbsence of care among community-dwelling older adults with dementia and functional limitations
Lin Z, Qian Y, Gill T, Hou X, Allore H, Chen S, Chen X. Absence of care among community-dwelling older adults with dementia and functional limitations. Nature Aging 2025, 5: 548-557. PMID: 40097773, PMCID: PMC12003173, DOI: 10.1038/s43587-025-00836-y.Peer-Reviewed Original ResearchConceptsActivities of daily livingFormal careDaily livingFunctional limitationsInstrumental activitiesInstrumental activities of daily living limitationsActivities of daily living limitationsInstrumental activities of daily livingLongitudinal survey dataCommunity-dwelling older adultsDaily living limitationsRegional development levelAbsence of careCare availabilityCare gapsSurvey dataCare servicesOlder adultsAdequate careEuropean countriesCareVulnerable populationsDevelopment levelInformation supportDementia
2024
Gender differences in the associations of circadian function with cognition among older persons with sleep disturbances
Pan Y, Cho G, Doyle M, Polisetty L, Burzynski C, Iannone L, Knauert M, Yaggi H, Gill T, Miner B. Gender differences in the associations of circadian function with cognition among older persons with sleep disturbances. Alzheimer's & Dementia 2024, 20: e089617. PMCID: PMC11716249, DOI: 10.1002/alz.089617.Peer-Reviewed Original ResearchMoCA scoresOlder adultsCognitive functionCommunity-dwelling older adultsCommunity-living adultsSleep disturbanceMontreal Cognitive AssessmentNo significant associationSleep-related factorsDays of actigraphyOlder personsActivity countsGender differencesPearson correlation coefficientMinority raceScore associationsInvestigate gender differencesCognitive AssessmentCircadian functionSlow wave sleepSignificant associationTotal sleep timeMoCANight of polysomnographyOlder men
2023
0733 The Association of Nocturia and Napping with Obstructive Sleep Apnea Among Older Adults with Insomnia and/or Daytime Sleepiness
Polisetty L, Pan Y, Iannone L, Knauert M, Yaggi K, Gill T, Miner B. 0733 The Association of Nocturia and Napping with Obstructive Sleep Apnea Among Older Adults with Insomnia and/or Daytime Sleepiness. Sleep 2023, 46: a322-a323. DOI: 10.1093/sleep/zsad077.0733.Peer-Reviewed Original ResearchApnea-hypopnea indexObstructive sleep apneaAssociation of nocturiaMinutes/weekDaytime sleepinessNap durationOlder adultsSleep apneaClaude D. Pepper Older Americans Independence CenterIntroduction Obstructive sleep apneaMean apnea-hypopnea indexHigher apnea-hypopnea indexCommunity-dwelling older adultsSymptoms of nocturiaCommunity-living adultsIdentification of OSAEvents/hrSelf-reported average numberHome-based polysomnographySymptoms of insomniaSelf-reported numberMore nocturiaHypopnea indexMean ageNocturiaPlatelet response to influenza vaccination reflects effects of aging
Konstorum A, Mohanty S, Zhao Y, Melillo A, Vander Wyk B, Nelson A, Tsang S, Blevins T, Belshe R, Chawla D, Rondina M, Gill T, Montgomery R, Allore H, Kleinstein S, Shaw A. Platelet response to influenza vaccination reflects effects of aging. Aging Cell 2023, 22: e13749. PMID: 36656789, PMCID: PMC9924941, DOI: 10.1111/acel.13749.Peer-Reviewed Original ResearchConceptsCommunity-dwelling older adultsPlatelet activationOlder adultsInfluenza vaccinationAge-associated chronic inflammationInfluence platelet functionRNA expressionPro-inflammatory diseasesAge-associated increasePlatelet activation pathwaysAge-associated differencesActivation pathwayPlatelet transcriptomeGeriatric conditionsChronic inflammationImmune responsePlatelet functionPlatelet responseSNF residentsVaccinationActivation responseYoung individualsProtein levelsAdultsYounger participants
2017
SELF-REPORTED PHYSICAL FUNCTION AS A PREDICTOR OF HOSPITALIZATION IN THE LIFE STUDY
Callahan K, Lovato L, Miller M, Marsh A, Gill T, Guralnik J, Kritchevsky S, Rejeski W. SELF-REPORTED PHYSICAL FUNCTION AS A PREDICTOR OF HOSPITALIZATION IN THE LIFE STUDY. Innovation In Aging 2017, 1: 249-250. PMCID: PMC6243682, DOI: 10.1093/geroni/igx004.919.Peer-Reviewed Original ResearchNumber of hospitalizationsFirst hospitalizationPhysical functionOlder adultsLifestyle interventionMAT-sfMobility Assessment Tool-short formBaseline comorbid conditionsBaseline physical functionCommunity-dwelling older adultsPredictors of hospitalizationRandomized clinical trialsU.S. academic medical centersSedentary community-dwelling older adultsAcademic medical centerComorbid conditionsDecreased riskPrescription medicationsCare coordinationClinical trialsElders StudyHospitalization dataMedical CenterHospitalizationSelf-report tool
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