2021
Pneumococcal vaccine uptake and vaccine effectiveness in older adults with invasive pneumococcal disease in Germany: A retrospective cohort study
Perniciaro S, van der Linden M. Pneumococcal vaccine uptake and vaccine effectiveness in older adults with invasive pneumococcal disease in Germany: A retrospective cohort study. The Lancet Regional Health - Europe 2021, 7: 100126. PMID: 34557837, PMCID: PMC8454757, DOI: 10.1016/j.lanepe.2021.100126.Peer-Reviewed Original ResearchInvasive pneumococcal diseasePneumococcal vaccine uptakeVaccine effectivenessPneumococcal vaccinationPneumococcal diseaseVaccine uptakeOlder adultsSerotype 3 invasive pneumococcal diseaseSerotype 3Indirect cohort methodOverall vaccine effectivenessRetrospective cohort studyInvestigator-initiated research grantIPD episodesCohort studyPneumococcal vaccinePolysaccharide vaccineVaccination statusPPV23Age groupsCohort methodVaccinationAdultsSerotypesVaccineBacterial Spectrum of Spontaneously Ruptured Otitis Media in a 7-Year, Longitudinal, Multicenter, Epidemiological Cross-Sectional Study in Germany
Imöhl M, Perniciaro S, Busse A, van der Linden M. Bacterial Spectrum of Spontaneously Ruptured Otitis Media in a 7-Year, Longitudinal, Multicenter, Epidemiological Cross-Sectional Study in Germany. Frontiers In Medicine 2021, 8: 675225. PMID: 34095179, PMCID: PMC8172772, DOI: 10.3389/fmed.2021.675225.Peer-Reviewed Original ResearchMiddle ear fluidNasopharyngeal swabsMEF samplesOtitis mediaAcute otitis media casesEpidemiological cross-sectional studyPCV7-vaccinated childrenRoutine pneumococcal vaccinationChildren 2 monthsNon-vaccinated childrenOtitis media casesCross-sectional studyNPS samplesOverall case numbersAOM patientsMEF isolatesPCV13 serotypesPCV7 serotypesPneumococcal vaccinationVaccination statusVaccine typesSerotype distributionBacterial etiologyDisease burdenEar fluid
2019
Regional variations in serotype distribution and vaccination status in children under six years of age with invasive pneumococcal disease in Germany
Perniciaro S, Imöhl M, Fitzner C, van der Linden M. Regional variations in serotype distribution and vaccination status in children under six years of age with invasive pneumococcal disease in Germany. PLOS ONE 2019, 14: e0210278. PMID: 30625215, PMCID: PMC6326516, DOI: 10.1371/journal.pone.0210278.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseaseVaccine-type invasive pneumococcal diseaseVT invasive pneumococcal diseaseUnvaccinated childrenSerotype distributionPneumococcal diseaseVaccination statusHigher oddsChildhood invasive pneumococcal diseaseDifferent serotype distributionSerotype of infectionVaccine-type serotypesNon-vaccine serotypesDose of vaccineYears of agePCV10 groupPCV13 groupPCV7 groupVaccine recommendationsAdministration scheduleContinued surveillanceProtective effectParticular serotypeInfectionSignificant predictors
2016
Effectiveness of Pneumococcal Conjugate Vaccines (PCV7 and PCV13) against Invasive Pneumococcal Disease among Children under Two Years of Age in Germany
van der Linden M, Falkenhorst G, Perniciaro S, Fitzner C, Imöhl M. Effectiveness of Pneumococcal Conjugate Vaccines (PCV7 and PCV13) against Invasive Pneumococcal Disease among Children under Two Years of Age in Germany. PLOS ONE 2016, 11: e0161257. PMID: 27526117, PMCID: PMC4985133, DOI: 10.1371/journal.pone.0161257.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseasePneumococcal conjugate vaccineAdjusted vaccine effectivenessTimeliness of vaccinationVaccine effectivenessPost boosterConjugate vaccinePneumococcal diseaseVaccine-type invasive pneumococcal diseaseType invasive pneumococcal diseaseIndirect cohort methodOverall vaccine effectivenessPneumococcal conjugate vaccinationSpecific vaccine effectivenessNumber of dosesYears of ageResidual casesTime of infectionConjugate vaccinationPCV13 serotypesPCV7 serotypesFirst doseIPD casesUnvaccinated childrenVaccination status
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