2025
Estimating the Serotype-Specific Association Between the Concentration of Vaccine-Induced Serum Antibodies and Protection Against Pneumococcal Colonization
Wong A, Warren J, Fitch L, Perniciaro S, Dagan R, Weinberger D. Estimating the Serotype-Specific Association Between the Concentration of Vaccine-Induced Serum Antibodies and Protection Against Pneumococcal Colonization. The Journal Of Infectious Diseases 2025, 232: e27-e34. PMID: 40036886, PMCID: PMC12308679, DOI: 10.1093/infdis/jiaf106.Peer-Reviewed Original ResearchHigher-valent PCVsPneumococcal conjugate vaccinePneumococcal colonizationVaccine-induced serum antibodiesRisk of colonizationSerum immunoglobulin GRandomized Controlled TrialsConjugate vaccinePCV13Clinical trialsSerum IgGImmune responseVaccinated childrenSevere diseaseVaccine effectivenessSerum antibodiesPCV20Serotype-specificImmunoglobulin GSerotypesColonIndirect protectionIgGVaccineTrials
2022
Reemergence of Invasive Pneumococcal Disease in Germany During the Spring and Summer of 2021
Perniciaro S, van der Linden M, Weinberger DM. Reemergence of Invasive Pneumococcal Disease in Germany During the Spring and Summer of 2021. Clinical Infectious Diseases 2022, 75: 1149-1153. PMID: 35136983, PMCID: PMC9383454, DOI: 10.1093/cid/ciac100.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseaseIPD surveillance dataIPD casesIPD incidencePneumococcal diseaseNonpharmaceutical interventionsVaccine-serotype invasive pneumococcal diseaseSurveillance dataCoronavirus disease 2019 (COVID-19) pandemicSARS-CoV-2Disease 2019 pandemicVaccine serotypesChildren 0Baseline valuesAge groupsSerotype-specific variationPercentage changeOverall casesIncidenceNPI strategiesIPD levelAge distributionDiseaseBaselineSerotypes
2021
Pneumococcal vaccine uptake and vaccine effectiveness in older adults with invasive pneumococcal disease in Germany: A retrospective cohort study
Perniciaro S, van der Linden M. Pneumococcal vaccine uptake and vaccine effectiveness in older adults with invasive pneumococcal disease in Germany: A retrospective cohort study. The Lancet Regional Health - Europe 2021, 7: 100126. PMID: 34557837, PMCID: PMC8454757, DOI: 10.1016/j.lanepe.2021.100126.Peer-Reviewed Original ResearchInvasive pneumococcal diseasePneumococcal vaccine uptakeVaccine effectivenessPneumococcal vaccinationPneumococcal diseaseVaccine uptakeOlder adultsSerotype 3 invasive pneumococcal diseaseSerotype 3Indirect cohort methodOverall vaccine effectivenessRetrospective cohort studyInvestigator-initiated research grantIPD episodesCohort studyPneumococcal vaccinePolysaccharide vaccineVaccination statusPPV23Age groupsCohort methodVaccinationAdultsSerotypesVaccine
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