2024
Long-term associations between ambient air pollution and self-perceived health status: Results from the population-based KORA-Fit study
Liao M, Zhang S, Wolf K, Bolte G, Laxy M, Schwettmann L, Peters A, Schneider A, Kraus U. Long-term associations between ambient air pollution and self-perceived health status: Results from the population-based KORA-Fit study. International Journal Of Hygiene And Environmental Health 2024, 264: 114513. PMID: 39719813, DOI: 10.1016/j.ijheh.2024.114513.Peer-Reviewed Original ResearchConceptsSelf-perceived healthLong-term air pollution exposureSelf-perceived health statusAir pollution exposurePoor SRHHealth statusAssociated with poor self-perceived healthPoor self-perceived healthPollution exposureInterquartile rangeLand-use regression modelsLogistic regressionGeocoded residential addressesParticle number concentrationFace-to-face interviewsCooperative Health ResearchEQ-5D index valueSelf-perceived stressAmbient air pollutionEQ-VAS scoresIQR increaseAir pollutionCross-sectional studyBody mass indexMultinomial logistic regressionSex-specific associations of environmental exposures with prevalent diabetes and obesity – Results from the KORA Fit study
Niedermayer F, Wolf K, Zhang S, Dallavalle M, Nikolaou N, Schwettmann L, Selsam P, Hoffmann B, Schneider A, Peters A. Sex-specific associations of environmental exposures with prevalent diabetes and obesity – Results from the KORA Fit study. Environmental Research 2024, 252: 118965. PMID: 38642640, DOI: 10.1016/j.envres.2024.118965.Peer-Reviewed Original ResearchConceptsAssociations of environmental exposuresAssociated with higher body-mass indexBody-mass indexHigh body-mass indexSex-specific associationsPrevalent diabetesEnvironmental exposuresAssociated with lower obesity prevalenceUrban menRural womenAssociated with diabetes prevalenceEvaluated sex-specific associationsLower obesity prevalenceAir pollutionAnalyzed cross-sectional dataGerman population-based cohortPopulation-based cohortSusceptibility to air pollutionSex-stratified analysesLack of greennessEffects of environmental exposuresFitness studiesSusceptibility to environmental exposuresSurrounding greennessCross-sectional data
2023
Long-term exposure to ambient air pollution and inflammatory response in the KORA study
Vogli M, Peters A, Wolf K, Thorand B, Herder C, Koenig W, Cyrys J, Maestri E, Marmiroli N, Karrasch S, Zhang S, Pickford R. Long-term exposure to ambient air pollution and inflammatory response in the KORA study. The Science Of The Total Environment 2023, 912: 169416. PMID: 38123091, DOI: 10.1016/j.scitotenv.2023.169416.Peer-Reviewed Original ResearchConceptsLong-term exposure to ambient air pollutionLong-term exposure to air pollutionExposure to ambient air pollutionExposure to air pollutionAmbient air pollutionAir pollutionUltrafine particlesParticulate matterIncrease of PM<sLand-use regression modelsAnnual mean concentrationsAtmospheric particulate matterAssociated with increased IL-6Adverse health effectsAssociated with higher concentrationsLand-useMean concentrationsParticipant's home addressPollutionLong-term studiesHealth effectsHigher concentrationsNitrogen oxidesMultiple linear regressionHome addressEffects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study
Ni W, Breitner S, Nikolaou N, Wolf K, Zhang S, Peters A, Herder C, Schneider A. Effects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study. Environmental Science And Technology 2023, 57: 12210-12221. PMID: 37552838, PMCID: PMC10448716, DOI: 10.1021/acs.est.3c00302.Peer-Reviewed Original ResearchConceptsKORA F4 studyBiomarkers of subclinical inflammationHigher risk of chronic diseasesF4 studyLevels of air pollutionLow air temperatureRisk of chronic diseasesPopulation-based KORA F4 studyCross-sectional analysisSubclinical inflammationAdverse health effectsCumulative lagAssociated with higher levelsAir pollutionAir temperatureChronic diseasesNeurotrophin-3Older participantsInterleukin-6Additive modelMedium-term effectsProximity extension assay technologyHealth effectsCardiovascular diseaseHigh riskLongitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study
Yao Y, Schneider A, Wolf K, Zhang S, Wang-Sattler R, Peters A, Breitner S. Longitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study. The Science Of The Total Environment 2023, 900: 165780. PMID: 37495154, DOI: 10.1016/j.scitotenv.2023.165780.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutantsAir PollutionCohort StudiesEnvironmental ExposureHumansNitrogen DioxideOzoneParticulate MatterConceptsExposure to ambient air pollutionExposure to air pollutionAmbient air pollutionAssociated with air pollutionExposure windowsBonferroni-corrected P value thresholdPopulation-based Cooperative Health ResearchShort-term exposure to air pollutionAir pollutionCooperative Health ResearchAir pollution exposureP-value thresholdAssociated with cardiopulmonary diseasesHealth researchLongitudinal associationsMedium-term exposureStudy participantsPollution exposureCohort studyCovariate-adjustedS4 surveyParticipantsAlterations of serum metabolitesSerum metabolitesPollutionHeat-related cardiorespiratory mortality: Effect modification by air pollution across 482 cities from 24 countries
Rai M, Stafoggia M, de'Donato F, Scortichini M, Zafeiratou S, Vazquez Fernandez L, Zhang S, Katsouyanni K, Samoli E, Rao S, Lavigne E, Guo Y, Kan H, Osorio S, Kyselý J, Urban A, Orru H, Maasikmets M, Jaakkola J, Ryti N, Pascal M, Hashizume M, Fook Sheng Ng C, Alahmad B, Hurtado Diaz M, De la Cruz Valencia C, Nunes B, Madureira J, Scovronick N, Garland R, Kim H, Lee W, Tobias A, Íñiguez C, Forsberg B, Åström C, Maria Vicedo-Cabrera A, Ragettli M, Leon Guo Y, Pan S, Li S, Gasparrini A, Sera F, Masselot P, Schwartz J, Zanobetti A, Bell M, Schneider A, Breitner S. Heat-related cardiorespiratory mortality: Effect modification by air pollution across 482 cities from 24 countries. Environment International 2023, 174: 107825. PMID: 36934570, DOI: 10.1016/j.envint.2023.107825.Peer-Reviewed Original ResearchConceptsAir pollutionRespiratory mortalityWHO air quality guidelinesElevated levels of air pollutionLevels of air pollutionAir quality guidelinesAmbient air pollutionLevel of pollutionCause-specific mortalityCardiovascular mortalityQuality guidelinesDaily death countsPollutant concentrationsCardiorespiratory mortalityPotential interactive effectsPollutionMitigation measuresPromote sustainable developmentMeta-analytic modelEffect modificationInteractive effects of heatSummer temperaturesSummer monthsExposure dataDeath counts
2022
Short-term effects of ultrafine particles on heart rate variability: A systematic review and meta-analysis
Zhang S, Breitner S, Pickford R, Lanki T, Okokon E, Morawska L, Samoli E, Rodopoulou S, Stafoggia M, Renzi M, Schikowski T, Zhao Q, Schneider A, Peters A. Short-term effects of ultrafine particles on heart rate variability: A systematic review and meta-analysis. Environmental Pollution 2022, 314: 120245. PMID: 36162563, DOI: 10.1016/j.envpol.2022.120245.Peer-Reviewed Original ResearchConceptsShort-term effects of ultrafine particlesMeta-analysisHeart rate variabilitySystematic reviewEffects of ultrafine particlesSynthesized effect estimatesShort-term effectsSingle-pollutant modelsStudy systematically reviewsRisk of biasMeta-analyzed studiesAssociated with decreased HRVNormal-to-normal intervalsRandom-effects modelR-R interval differencesWeb of ScienceOutcome measuresEffect estimatesPooled estimatesRate variabilityExposure to ambient ultrafine particlesEpidemiological studiesMeta-analyzedRatio of low-frequency to high-frequency powerCardiovascular diseaseCirculating microRNAs as putative mediators in the association between short-term exposure to ambient air pollution and cardiovascular biomarkers
Chen H, Zhang S, Yu B, Xu Y, Rappold A, Diaz-Sanchez D, Samet J, Tong H. Circulating microRNAs as putative mediators in the association between short-term exposure to ambient air pollution and cardiovascular biomarkers. Ecotoxicology And Environmental Safety 2022, 239: 113604. PMID: 35576800, PMCID: PMC9167781, DOI: 10.1016/j.ecoenv.2022.113604.Peer-Reviewed Original ResearchConceptsExposure to ambient air pollutionAmbient air pollutionExposure to air pollutionAir pollutionShort-term exposure to ambient PM<sub>2.5</sub> waExposure to ambient PM<sub>2.5</sub>Short-term exposure to ambient fine particulate matterShort-term exposure to ambient air pollutionAmbient PM<sub>2.5</sub>Exposure to ambient fine particulate matterAmbient fine particulate matterEffects of exposure to air pollutionAir quality monitoring stationsEffects of air pollution exposureFine particulate matterQuality monitoring stationsAir pollutant concentrationsResearch Triangle area of North CarolinaAir pollution exposureTriangle area of North CarolinaBlood lipid biomarkersResearch Triangle areaPollutant concentrationsParticulate matterPollution exposureLung Function and Short-Term Ambient Air Pollution Exposure: Differential Impacts of Omega-3 and Omega-6 Fatty Acids.
Tong H, Zhang S, Shen W, Chen H, Salazar C, Schneider A, Rappold A, Diaz-Sanchez D, Devlin R, Samet J. Lung Function and Short-Term Ambient Air Pollution Exposure: Differential Impacts of Omega-3 and Omega-6 Fatty Acids. Annals Of The American Thoracic Society 2022, 19: 583-593. PMID: 34797737, DOI: 10.1513/annalsats.202107-767oc.Peer-Reviewed Original ResearchMeSH KeywordsAdultAir PollutantsAir PollutionEnvironmental ExposureFatty Acids, Omega-6HumansLungParticulate MatterConceptsAmbient air pollutionAir pollutionParticulate matterShort-term exposure to ambient air pollutionShort-term ambient air pollution exposureNational Ambient Air Quality StandardsExposure to ambient air pollutionAmbient Air Quality StandardsHealth effects of air pollutionAmbient air pollution exposureExposure to air pollutionEffects of air pollutionFine particulate matterAir quality standardsAir pollution exposureAssociated with adverse respiratory effectsPollution exposureLevels of ozoneElevated ozone levelsN-3 FA intakePollutionQuality standardsOzone levelsAssociated with ozoneHealth effectsOmega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution
Chen H, Zhang S, Shen W, Salazar C, Schneider A, Wyatt L, Rappold A, Diaz-Sanchez D, Devlin R, Samet J, Tong H. Omega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution. Particle And Fibre Toxicology 2022, 19: 12. PMID: 35139860, PMCID: PMC8826673, DOI: 10.1186/s12989-022-00451-4.Peer-Reviewed Original ResearchConceptsExposure to PM2.5Air pollutionEffects of exposure to fine particulate matterShort-term exposure to PM2.5National Ambient Air Quality StandardsU.S. National Ambient Air Quality StandardsExposure to fine particulate matterConcentrations of ambient PM2.5Air quality monitoring stationsAmbient Air Quality StandardsFine particulate matterAir pollutant concentrationsAir quality standardsQuality monitoring stationsResearch Triangle area of North CarolinaAmbient air pollutionResultsThe average concentrationTriangle area of North CarolinaResearch Triangle areaAmbient PM2.5Daily PM2.5Pollutant concentrationsParticulate matterPM2.5Monitoring stations
2021
The influence of dietary intake of omega-3 polyunsaturated fatty acids on the association between short-term exposure to ambient nitrogen dioxide and respiratory and cardiovascular outcomes among healthy adults
Chen H, Zhang S, Shen W, Salazar C, Schneider A, Wyatt L, Rappold A, Diaz-Sanchez D, Devlin R, Samet J, Tong H. The influence of dietary intake of omega-3 polyunsaturated fatty acids on the association between short-term exposure to ambient nitrogen dioxide and respiratory and cardiovascular outcomes among healthy adults. Environmental Health 2021, 20: 123. PMID: 34872587, PMCID: PMC8650256, DOI: 10.1186/s12940-021-00809-9.Peer-Reviewed Original ResearchConceptsNational Ambient Air Quality StandardsExposure to ambient nitrogen dioxideOmega-3 groupAmbient nitrogen dioxideOmega-3 PUFA intakeOmega-3 polyunsaturated fatty acidsHeart rate variabilityBlood lipidsAmbient NO2NO2 concentrationsVascular functionLung functionExposure to fine particulate matterAir quality monitoring stationsConcentrations of ambient NO2Interquartile rangeAmbient Air Quality StandardsNitrogen dioxideShort-term exposure to NO2PUFA intakeCardiovascular outcomesFine particulate matterAir quality standardsQuality monitoring stationsResearch Triangle area of North CarolinaA systematic review on the association between total and cardiopulmonary mortality/morbidity or cardiovascular risk factors with long-term exposure to increased or decreased ambient temperature
Zafeiratou S, Samoli E, Dimakopoulou K, Rodopoulou S, Analitis A, Gasparrini A, Stafoggia M, De' Donato F, Rao S, Monteiro A, Rai M, Zhang S, Breitner S, Aunan K, Schneider A, Katsouyanni K, team E. A systematic review on the association between total and cardiopulmonary mortality/morbidity or cardiovascular risk factors with long-term exposure to increased or decreased ambient temperature. The Science Of The Total Environment 2021, 772: 145383. PMID: 33578152, DOI: 10.1016/j.scitotenv.2021.145383.Peer-Reviewed Original ResearchConceptsHealth outcomesRisk of biasCardiovascular risk factorsSystematic reviewCrude exposure assessmentShort-term mortality displacementDiverse health outcomesAssociation of long-termRisk factorsHigher obesityEffect modificationInadequate adjustmentCardiopulmonary mortalityWorld Health OrganizationEffect modifiersOutcome prevalenceMortality displacementAnnual temperature indicesLong-term exposureAir pollutionCardiovascular mortalityHealthHealth OrganizationHealth effectsRespiratory outcomes
2018
Short-term effects of fine particulate matter and ozone on the cardiac conduction system in patients undergoing cardiac catheterization
Zhang S, Breitner S, Cascio W, Devlin R, Neas L, Diaz-Sanchez D, Kraus W, Schwartz J, Hauser E, Peters A, Schneider A. Short-term effects of fine particulate matter and ozone on the cardiac conduction system in patients undergoing cardiac catheterization. Particle And Fibre Toxicology 2018, 15: 38. PMID: 30305173, PMCID: PMC6180522, DOI: 10.1186/s12989-018-0275-z.Peer-Reviewed Original ResearchConceptsAssociations of PM2.5Particulate matterAir pollutionShort-term exposure to air pollutionDaily concentrations of PM2.5Short-term effects of particulate matterEffects of fine particulate matterShort-term effects of fine particulate matterExposure to air pollutionEffects of particulate matterConcentrations of PM2.5Fine particulate matterPollution-induced changesAir pollution effectsInvestigate short-term effectsDaily concentrationsPM2.5Pollution effectsAssociation of O3Temporal lag structureAerodynamic diameterDistributed-lag modelParticipant's home addressExposure modelO3
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