2024
Long-term associations between ambient air pollution and self-perceived health status: Results from the population-based KORA-Fit study
Liao M, Zhang S, Wolf K, Bolte G, Laxy M, Schwettmann L, Peters A, Schneider A, Kraus U. Long-term associations between ambient air pollution and self-perceived health status: Results from the population-based KORA-Fit study. International Journal Of Hygiene And Environmental Health 2024, 264: 114513. PMID: 39719813, DOI: 10.1016/j.ijheh.2024.114513.Peer-Reviewed Original ResearchConceptsSelf-perceived healthLong-term air pollution exposureSelf-perceived health statusAir pollution exposurePoor SRHHealth statusAssociated with poor self-perceived healthPoor self-perceived healthPollution exposureInterquartile rangeLand-use regression modelsLogistic regressionGeocoded residential addressesParticle number concentrationFace-to-face interviewsCooperative Health ResearchEQ-5D index valueSelf-perceived stressAmbient air pollutionEQ-VAS scoresIQR increaseAir pollutionCross-sectional studyBody mass indexMultinomial logistic regressionShort-term effects of temperature and air pollution on mortality in Norway: a nationwide cohort-based study
Rao S, Zhang S, Ahimbisibwe A, Bekkevold T, Di Ruscio F, Palomares A, Frohn L, Geels C, Fernández L, Schneider A. Short-term effects of temperature and air pollution on mortality in Norway: a nationwide cohort-based study. Frontiers In Environmental Health 2024, 3: 1419261. DOI: 10.3389/fenvh.2024.1419261.Peer-Reviewed Original ResearchNatural-cause mortalityCause-specific mortalityPotential effect modificationLevels of air pollutionAir pollutionEffect modificationCardiovascular mortalityIncreased risk of respiratory mortalityIncreased riskRisk of respiratory mortalityConditional logistic regression modelsConcentrations of fine particulate matterHistory of cardiovascular diseaseElevated air pollution levelsCase-crossover studyRisk of cardiovascular mortalityRegression modelsIncreased risk of cardiovascular mortalityShort-term associationsFine particulate matterAir pollutant concentrationsCohort-based studyAir pollution levelsSubgroup of participantsLogistic regression modelsEffect modification of air pollution on the association between heat and mortality in five European countries
Zhang S, Breitner S, Stafoggia M, Donato F, Samoli E, Zafeiratou S, Katsouyanni K, Rao S, Diz-Lois Palomares A, Gasparrini A, Masselot P, Nikolaou N, Aunan K, Peters A, Schneider A. Effect modification of air pollution on the association between heat and mortality in five European countries. Environmental Research 2024, 263: 120023. PMID: 39293751, DOI: 10.1016/j.envres.2024.120023.Peer-Reviewed Original ResearchHigh PM levelsEffect modificationAir pollutionHeat-related mortalityEffect modification of air pollutantsPM levelsRural dataHighest O<sub>3</sub> level waDaily non-accidental deathsPotential effect modificationMixed-effects meta-regressionRandom-effects meta-analysisAttica region of GreecePoisson regression modelsHeat-mortality associationsAir pollutant concentrationsAir pollution levelsImprove air qualityTime-series studyHeat-related mortality riskHeat-related health impactsNon-accidental deathsSmall area dataTemperature-mortality relationshipPollutant concentrationsSex-specific associations of environmental exposures with prevalent diabetes and obesity – Results from the KORA Fit study
Niedermayer F, Wolf K, Zhang S, Dallavalle M, Nikolaou N, Schwettmann L, Selsam P, Hoffmann B, Schneider A, Peters A. Sex-specific associations of environmental exposures with prevalent diabetes and obesity – Results from the KORA Fit study. Environmental Research 2024, 252: 118965. PMID: 38642640, DOI: 10.1016/j.envres.2024.118965.Peer-Reviewed Original ResearchConceptsAssociations of environmental exposuresAssociated with higher body-mass indexBody-mass indexHigh body-mass indexSex-specific associationsPrevalent diabetesEnvironmental exposuresAssociated with lower obesity prevalenceUrban menRural womenAssociated with diabetes prevalenceEvaluated sex-specific associationsLower obesity prevalenceAir pollutionAnalyzed cross-sectional dataGerman population-based cohortPopulation-based cohortSusceptibility to air pollutionSex-stratified analysesLack of greennessEffects of environmental exposuresFitness studiesSusceptibility to environmental exposuresSurrounding greennessCross-sectional data
2023
Long-term exposure to ambient air pollution and inflammatory response in the KORA study
Vogli M, Peters A, Wolf K, Thorand B, Herder C, Koenig W, Cyrys J, Maestri E, Marmiroli N, Karrasch S, Zhang S, Pickford R. Long-term exposure to ambient air pollution and inflammatory response in the KORA study. The Science Of The Total Environment 2023, 912: 169416. PMID: 38123091, DOI: 10.1016/j.scitotenv.2023.169416.Peer-Reviewed Original ResearchConceptsLong-term exposure to ambient air pollutionLong-term exposure to air pollutionExposure to ambient air pollutionExposure to air pollutionAmbient air pollutionAir pollutionUltrafine particlesParticulate matterIncrease of PM<sLand-use regression modelsAnnual mean concentrationsAtmospheric particulate matterAssociated with increased IL-6Adverse health effectsAssociated with higher concentrationsLand-useMean concentrationsParticipant's home addressPollutionLong-term studiesHealth effectsHigher concentrationsNitrogen oxidesMultiple linear regressionHome addressCorrigendum to “Longitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study” [Sci. Total Environ. 900 (2023) 165780]
Yao Y, Schneider A, Wolf K, Zhang S, Wang-Sattler R, Prehn C, Adamski J, Peters A, Breitner S. Corrigendum to “Longitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study” [Sci. Total Environ. 900 (2023) 165780]. The Science Of The Total Environment 2023, 905: 167050. PMID: 37734230, DOI: 10.1016/j.scitotenv.2023.167050.Peer-Reviewed Original ResearchEffects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study
Ni W, Breitner S, Nikolaou N, Wolf K, Zhang S, Peters A, Herder C, Schneider A. Effects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study. Environmental Science And Technology 2023, 57: 12210-12221. PMID: 37552838, PMCID: PMC10448716, DOI: 10.1021/acs.est.3c00302.Peer-Reviewed Original ResearchConceptsKORA F4 studyBiomarkers of subclinical inflammationHigher risk of chronic diseasesF4 studyLevels of air pollutionLow air temperatureRisk of chronic diseasesPopulation-based KORA F4 studyCross-sectional analysisSubclinical inflammationAdverse health effectsCumulative lagAssociated with higher levelsAir pollutionAir temperatureChronic diseasesNeurotrophin-3Older participantsInterleukin-6Additive modelMedium-term effectsProximity extension assay technologyHealth effectsCardiovascular diseaseHigh riskLongitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study
Yao Y, Schneider A, Wolf K, Zhang S, Wang-Sattler R, Peters A, Breitner S. Longitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study. The Science Of The Total Environment 2023, 900: 165780. PMID: 37495154, DOI: 10.1016/j.scitotenv.2023.165780.Peer-Reviewed Original ResearchConceptsExposure to ambient air pollutionExposure to air pollutionAmbient air pollutionAssociated with air pollutionExposure windowsBonferroni-corrected P value thresholdPopulation-based Cooperative Health ResearchShort-term exposure to air pollutionAir pollutionCooperative Health ResearchAir pollution exposureP-value thresholdAssociated with cardiopulmonary diseasesHealth researchLongitudinal associationsMedium-term exposureStudy participantsPollution exposureCohort studyCovariate-adjustedS4 surveyParticipantsAlterations of serum metabolitesSerum metabolitesPollutionHeat-related cardiorespiratory mortality: Effect modification by air pollution across 482 cities from 24 countries
Rai M, Stafoggia M, de'Donato F, Scortichini M, Zafeiratou S, Vazquez Fernandez L, Zhang S, Katsouyanni K, Samoli E, Rao S, Lavigne E, Guo Y, Kan H, Osorio S, Kyselý J, Urban A, Orru H, Maasikmets M, Jaakkola J, Ryti N, Pascal M, Hashizume M, Fook Sheng Ng C, Alahmad B, Hurtado Diaz M, De la Cruz Valencia C, Nunes B, Madureira J, Scovronick N, Garland R, Kim H, Lee W, Tobias A, Íñiguez C, Forsberg B, Åström C, Maria Vicedo-Cabrera A, Ragettli M, Leon Guo Y, Pan S, Li S, Gasparrini A, Sera F, Masselot P, Schwartz J, Zanobetti A, Bell M, Schneider A, Breitner S. Heat-related cardiorespiratory mortality: Effect modification by air pollution across 482 cities from 24 countries. Environment International 2023, 174: 107825. PMID: 36934570, DOI: 10.1016/j.envint.2023.107825.Peer-Reviewed Original ResearchConceptsAir pollutionRespiratory mortalityWHO air quality guidelinesElevated levels of air pollutionLevels of air pollutionAir quality guidelinesAmbient air pollutionLevel of pollutionCause-specific mortalityCardiovascular mortalityQuality guidelinesDaily death countsPollutant concentrationsCardiorespiratory mortalityPotential interactive effectsPollutionMitigation measuresPromote sustainable developmentMeta-analytic modelEffect modificationInteractive effects of heatSummer temperaturesSummer monthsExposure dataDeath counts
2022
Longitudinal associations between metabolites and long-term exposure to ambient air pollution: Results from the KORA cohort study
Yao Y, Schneider A, Wolf K, Zhang S, Wang-Sattler R, Peters A, Breitner S. Longitudinal associations between metabolites and long-term exposure to ambient air pollution: Results from the KORA cohort study. Environment International 2022, 170: 107632. PMID: 36402035, DOI: 10.1016/j.envint.2022.107632.Peer-Reviewed Original ResearchConceptsLong-term exposure to air pollutionExposure to air pollutionLand-use regressionAir pollutionPhosphatidylcholine acyl-alkylParticulate matterLong-term exposure to ambient air pollutionAverage concentrations of ultrafine particlesExposure to ambient air pollutionEstimate annual average concentrationsAssociated with cardiopulmonary diseasesAmbient air pollutionConcentrations of ultrafine particlesPopulation-based Cooperative Health ResearchAmbient pollutantsLand-useAerodynamic diameterCooperative Health ResearchPollutionS4 surveyCoarse particlesFine particlesMixed-effects regression modelsUltrafine particlesNitrogen oxidesInteractive effects of heat and air pollution on mortality in Europe using small area data – Results of the exhaustion project
De Donato F, Stafoggia M, Breitner S, Rai M, Zhang S, Samoli E, Katsouyanni K, Zafeiratou S, Gasparrini A, Masselot P, Vazquez-Fernandez L, Diz-Lois Palomares A, Rao S, Aunan K, Schneider A. Interactive effects of heat and air pollution on mortality in Europe using small area data – Results of the exhaustion project. ISEE Conference Abstracts 2022, 2022 DOI: 10.1289/isee.2022.o-op-228.Peer-Reviewed Original ResearchInteractive effects of heatAir pollutionLongitudinal associations between metabolites and long-term exposure to ambient air pollution: results from the KORA cohort study
Yao Y, Schneider A, Wolf K, Zhang S, Wang-Sattler R, Peters A, Breitner S. Longitudinal associations between metabolites and long-term exposure to ambient air pollution: results from the KORA cohort study. ISEE Conference Abstracts 2022, 2022 DOI: 10.1289/isee.2022.o-op-003.Peer-Reviewed Original ResearchShort-term heat effects and effect modification by ambient air pollution on cardiovascular and respiratory mortality across 148 cities from 13 European countries – Results of the EXHAUSTION project
Rai M, Stafoggia M, De'Donato F, Gasparrini A, Masselot P, Samoli E, Zafeiratou S, Katsouyanni K, Rao S, Vazquez Fernandez L, Zhang S, Aunan K, Peters A, Schneider A, Breitner S. Short-term heat effects and effect modification by ambient air pollution on cardiovascular and respiratory mortality across 148 cities from 13 European countries – Results of the EXHAUSTION project. ISEE Conference Abstracts 2022, 2022 DOI: 10.1289/isee.2022.o-sy-053.Peer-Reviewed Original ResearchCirculating microRNAs as putative mediators in the association between short-term exposure to ambient air pollution and cardiovascular biomarkers
Chen H, Zhang S, Yu B, Xu Y, Rappold A, Diaz-Sanchez D, Samet J, Tong H. Circulating microRNAs as putative mediators in the association between short-term exposure to ambient air pollution and cardiovascular biomarkers. Ecotoxicology And Environmental Safety 2022, 239: 113604. PMID: 35576800, PMCID: PMC9167781, DOI: 10.1016/j.ecoenv.2022.113604.Peer-Reviewed Original ResearchConceptsExposure to ambient air pollutionAmbient air pollutionExposure to air pollutionAir pollutionShort-term exposure to ambient PM<sub>2.5</sub> waExposure to ambient PM<sub>2.5</sub>Short-term exposure to ambient fine particulate matterShort-term exposure to ambient air pollutionAmbient PM<sub>2.5</sub>Exposure to ambient fine particulate matterAmbient fine particulate matterEffects of exposure to air pollutionAir quality monitoring stationsEffects of air pollution exposureFine particulate matterQuality monitoring stationsAir pollutant concentrationsResearch Triangle area of North CarolinaAir pollution exposureTriangle area of North CarolinaBlood lipid biomarkersResearch Triangle areaPollutant concentrationsParticulate matterPollution exposureLung Function and Short-Term Ambient Air Pollution Exposure: Differential Impacts of Omega-3 and Omega-6 Fatty Acids.
Tong H, Zhang S, Shen W, Chen H, Salazar C, Schneider A, Rappold A, Diaz-Sanchez D, Devlin R, Samet J. Lung Function and Short-Term Ambient Air Pollution Exposure: Differential Impacts of Omega-3 and Omega-6 Fatty Acids. Annals Of The American Thoracic Society 2022, 19: 583-593. PMID: 34797737, DOI: 10.1513/annalsats.202107-767oc.Peer-Reviewed Original ResearchConceptsAmbient air pollutionAir pollutionParticulate matterShort-term exposure to ambient air pollutionShort-term ambient air pollution exposureNational Ambient Air Quality StandardsExposure to ambient air pollutionAmbient Air Quality StandardsHealth effects of air pollutionAmbient air pollution exposureExposure to air pollutionEffects of air pollutionFine particulate matterAir quality standardsAir pollution exposureAssociated with adverse respiratory effectsPollution exposureLevels of ozoneElevated ozone levelsN-3 FA intakePollutionQuality standardsOzone levelsAssociated with ozoneHealth effectsOmega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution
Chen H, Zhang S, Shen W, Salazar C, Schneider A, Wyatt L, Rappold A, Diaz-Sanchez D, Devlin R, Samet J, Tong H. Omega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution. Particle And Fibre Toxicology 2022, 19: 12. PMID: 35139860, PMCID: PMC8826673, DOI: 10.1186/s12989-022-00451-4.Peer-Reviewed Original ResearchConceptsExposure to PM2.5Air pollutionEffects of exposure to fine particulate matterShort-term exposure to PM2.5National Ambient Air Quality StandardsU.S. National Ambient Air Quality StandardsExposure to fine particulate matterConcentrations of ambient PM2.5Air quality monitoring stationsAmbient Air Quality StandardsFine particulate matterAir pollutant concentrationsAir quality standardsQuality monitoring stationsResearch Triangle area of North CarolinaAmbient air pollutionResultsThe average concentrationTriangle area of North CarolinaResearch Triangle areaAmbient PM2.5Daily PM2.5Pollutant concentrationsParticulate matterPM2.5Monitoring stations
2021
Short-term effects of temperature on cardiovascular and respiratory mortality and its modification by air pollution in German cities
Rai M, Breitner S, Zhang S, De‘donato F, Staffogia M, Scortichini M, Aunan K, Peters A, Schneider A. Short-term effects of temperature on cardiovascular and respiratory mortality and its modification by air pollution in German cities. ISEE Conference Abstracts 2021, 2021 DOI: 10.1289/isee.2021.p-386.Peer-Reviewed Original ResearchA systematic review on the association between total and cardiopulmonary mortality/morbidity or cardiovascular risk factors with long-term exposure to increased or decreased ambient temperature
Zafeiratou S, Samoli E, Dimakopoulou K, Rodopoulou S, Analitis A, Gasparrini A, Stafoggia M, De' Donato F, Rao S, Monteiro A, Rai M, Zhang S, Breitner S, Aunan K, Schneider A, Katsouyanni K, team E. A systematic review on the association between total and cardiopulmonary mortality/morbidity or cardiovascular risk factors with long-term exposure to increased or decreased ambient temperature. The Science Of The Total Environment 2021, 772: 145383. PMID: 33578152, DOI: 10.1016/j.scitotenv.2021.145383.Peer-Reviewed Original ResearchConceptsHealth outcomesRisk of biasCardiovascular risk factorsSystematic reviewCrude exposure assessmentShort-term mortality displacementDiverse health outcomesAssociation of long-termRisk factorsHigher obesityEffect modificationInadequate adjustmentCardiopulmonary mortalityWorld Health OrganizationEffect modifiersOutcome prevalenceMortality displacementAnnual temperature indicesLong-term exposureAir pollutionCardiovascular mortalityHealthHealth OrganizationHealth effectsRespiratory outcomesLongitudinal associations between ambient air pollution and insulin sensitivity: results from the KORA cohort study
Zhang S, Mwiberi S, Pickford R, Breitner S, Huth C, Koenig W, Rathmann W, Herder C, Roden M, Cyrys J, Peters A, Wolf K, Schneider A. Longitudinal associations between ambient air pollution and insulin sensitivity: results from the KORA cohort study. The Lancet Planetary Health 2021, 5: e39-e49. PMID: 33421408, DOI: 10.1016/s2542-5196(20)30275-8.Peer-Reviewed Original ResearchConceptsLong-term air pollution exposureAir pollution exposureAnnual average air pollutant concentrationsAssociation of air pollutionAverage air pollutant concentrationsPollution exposureLongitudinal associationsType 2 diabetesAir pollutant concentrationsLand-use regression modelsAssociated with air pollution exposureExposure to air pollutionCooperative Health ResearchAmbient air pollutionRegression modelsConcentrations of fasting insulinKORA F4German Federal Ministry of EducationHealth researchIQR incrementAir pollutionAnnual rateKORA cohortDevelopment of type 2 diabetesKORA S4
2020
Association of Long-Term Air Pollution with Prevalence and Incidence of Distal Sensorimotor Polyneuropathy: KORA F4/FF4 Study
Herder C, Schneider A, Zhang S, Wolf K, Maalmi H, Huth C, Pickford R, Laxy M, Bönhof G, Koenig W, Rathmann W, Roden M, Peters A, Thorand B, Ziegler D. Association of Long-Term Air Pollution with Prevalence and Incidence of Distal Sensorimotor Polyneuropathy: KORA F4/FF4 Study. Environmental Health Perspectives 2020, 128: 127013. PMID: 33356516, PMCID: PMC7757787, DOI: 10.1289/ehp7311.Peer-Reviewed Original ResearchConceptsIncident DSPNDistal sensorimotor polyneuropathyAssociated with incident DSPNObese participantsType 2 diabetesNonobese participantsPopulation-based study of older individualsDevelopment of distal sensorimotor polyneuropathyAnnual average air pollutant concentrationsAssociation of air pollutionRates of type 2 diabetesAverage air pollutant concentrationsRobust error varianceCooperative Health ResearchAssociated with higher prevalenceStudies of older individualsPopulation-based studyPoisson regression modelsLong-term air pollutionCross-sectional analysisAir pollutionParticipating residentsKORA F4Health researchYears of age
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