2025
New tsetse (Glossina fuscipes fuscipes) genomes generated from wild and laboratory‐reared specimens
Bruzzese D, Weiss B, Echodu R, Mireji P, Abd‐Alla A, Aksoy S. New tsetse (Glossina fuscipes fuscipes) genomes generated from wild and laboratory‐reared specimens. Insect Science 2025 PMID: 40509668, PMCID: PMC12353960, DOI: 10.1111/1744-7917.70085.Peer-Reviewed Original ResearchHigh-quality genomesVectors of African trypanosomesSingle-copy homologsPopulation-level variationBUSCO scoreUnique orthologsAssembled genomeAnimal African trypanosomiasesGenetic diversityNatural wild populationsNanopore sequencingGenomeWild populationsLong-term captivityAfrican trypanosomesLaboratory linesGlossina fuscipes fuscipesGeographical originOrthologsLaboratory-reared specimensQV scoreVector biologyCentral African RepublicNorthwestern UgandaFlies
2019
Colonization of the tsetse fly midgut with commensal Kosakonia cowanii Zambiae inhibits trypanosome infection establishment
Weiss BL, Maltz MA, Vigneron A, Wu Y, Walter KS, O’Neill M, Wang J, Aksoy S. Colonization of the tsetse fly midgut with commensal Kosakonia cowanii Zambiae inhibits trypanosome infection establishment. PLOS Pathogens 2019, 15: e1007470. PMID: 30817773, PMCID: PMC6394900, DOI: 10.1371/journal.ppat.1007470.Peer-Reviewed Original ResearchConceptsRefractory phenotypeEnormous socio-economic burdenWild-type counterpartsInfection establishmentSocio-economic burdenMidgut environmentEntomopathogenic Serratia marcescensEndemic regionsPathogenic trypanosomesInfectionStable infectionAdverse effectsAnimal African trypanosomiasesVector competenceGutCurrent disease control strategiesSaharan AfricaDisease control strategiesSurvivalSerratia marcescensTsetse gutExogenous bacteriumFly survivalNovel strategyPhenotype
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply