2021
Cumulus cells of euploid versus whole chromosome 21 aneuploid embryos reveal differentially expressed genes
Tiegs AW, Titus S, Mehta S, Garcia-Milian R, Seli E, Scott RT. Cumulus cells of euploid versus whole chromosome 21 aneuploid embryos reveal differentially expressed genes. Reproductive BioMedicine Online 2021, 43: 614-626. PMID: 34417138, DOI: 10.1016/j.rbmo.2021.06.015.Peer-Reviewed Original ResearchConceptsSerum response factorCumulus cellsDifferential gene expressionRNA sequencing analysisGene expression analysisIngenuity Pathway AnalysisCellular communication network factor 1Embryo developmental competenceExpression analysisPreimplantation embryo qualityGene expressionPathway analysisSegment polarity protein 2Sequencing analysisGenesProtein 2Response factorTrisomy 21Factor 1Developmental competenceAneuploid embryosReal-time polymerase chain reaction assaysDevelopment of biomarkersEmbryosCells
2017
HOW DOES THE SILENCING OF THE INFLAMMATION MEDIATOR GENE: FAT10, EXTEND LIFESPAN IN MICE?
Canaan A, Arjona C, Gulez B, Seay M, Zhang J, Henegariu O, Garcia Milian R. HOW DOES THE SILENCING OF THE INFLAMMATION MEDIATOR GENE: FAT10, EXTEND LIFESPAN IN MICE? Innovation In Aging 2017, 1: 978-978. PMCID: PMC6185008, DOI: 10.1093/geroni/igx004.3533.Peer-Reviewed Original ResearchDifferential gene expressionRNA sequence analysisStem cell populationNovel mechanistic insightsAdipogenic transcription factorsAdipocyte metabolic functionMammalian agingHematopoietic stem cellsTranscription factorsGene expressionPathway analysisPleiotropic natureKnockout miceFAT10 geneMaximal lifespanDruggable targetsMetabolic functionsStem cellsTRANSFAC analysisFAT10Mediator genesMechanistic insightsMost tissuesCell populationsGenes
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