2025
Access to Electrophysiologic Care for Medicare Beneficiaries Across the United States: Travel Distance and Time to Nearest Clinician, 2013-2020
Khaloo P, Wheelock K, Hanna J, Kapadia S, Pedroso A, Nabi W, Aminorroaya A, Freeman J, Khera R. Access to Electrophysiologic Care for Medicare Beneficiaries Across the United States: Travel Distance and Time to Nearest Clinician, 2013-2020. Heart Rhythm 2025 PMID: 40935055, DOI: 10.1016/j.hrthm.2025.09.013.Peer-Reviewed Original ResearchElectrophysiological careMedicare beneficiariesZip codesPercentage of Hispanic residentsSocio-economically disadvantaged groupsResidents of rural areasAnnual income <Multivariate logistic regression modelHigh school educationLogistic regression modelsUnited StatesUS zip codesSociodemographic factorsCardiovascular careOlder adultsGeographic disparitiesHealthcare ResearchPractitioner dataHispanic residentsLong travel timesMedicare providersPacemaker implantationMedicare PhysicianAF ablationUS countiesArtificial intelligence-enhanced echocardiography in cardiovascular disease management
Myhre P, Grenne B, Asch F, Delgado V, Khera R, Lafitte S, Lang R, Pellikka P, Sengupta P, Vemulapalli S, Lam C. Artificial intelligence-enhanced echocardiography in cardiovascular disease management. Nature Reviews Cardiology 2025, 1-19. PMID: 40764834, DOI: 10.1038/s41569-025-01197-0.Peer-Reviewed Original ResearchLeveraging AI-enhanced digital health with consumer devices for scalable cardiovascular screening, prediction, and monitoring
Pedroso A, Khera R. Leveraging AI-enhanced digital health with consumer devices for scalable cardiovascular screening, prediction, and monitoring. Npj Cardiovascular Health 2025, 2: 34. PMID: 40620667, PMCID: PMC12221986, DOI: 10.1038/s44325-025-00071-9.Peer-Reviewed Original ResearchArtificial intelligenceConsumer devicesConsumer wearablesPortable devicesCardiovascular careDigital healthTraditional care settingsDigital health toolsTraditional care modelResource-constrained settingsCare modelPersonalized risk assessmentCare settingsCardiovascular screeningHealth toolsWearableDevicesLow-cost alternativeIntelligenceCareHarnessing Artificial Intelligence for Innovation in Interventional Cardiovascular Care
Aminorroaya A, Biswas D, Pedroso A, Khera R. Harnessing Artificial Intelligence for Innovation in Interventional Cardiovascular Care. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 102562. PMID: 40230673, PMCID: PMC11993883, DOI: 10.1016/j.jscai.2025.102562.Peer-Reviewed Original ResearchClinical careCommunity-based screening programCare quality outcomesPatient outcomesPatient-focused careHarness artificial intelligenceArtificial intelligencePotential of AIImprove patient outcomesIndividualized clinical careTransform careTransform clinical practiceCardiovascular careScreening programHealth dataQuality outcomesCareClinical workflowClinical tasksAcute coronary syndromeClinical practiceHeart diseaseAI-driven technologiesInterventionAI-enabled
2024
Cardiovascular care with digital twin technology in the era of generative artificial intelligence
Thangaraj P, Benson S, Oikonomou E, Asselbergs F, Khera R. Cardiovascular care with digital twin technology in the era of generative artificial intelligence. European Heart Journal 2024, 45: 4808-4821. PMID: 39322420, PMCID: PMC11638093, DOI: 10.1093/eurheartj/ehae619.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGenerative artificial intelligenceCardiovascular careCardiovascular medicinePersonalized cardiovascular careArtificial intelligenceSimulations of clinical scenariosData modalitiesPrediction of disease riskClinical decision-makingIn silico replicationPersonalized patient careDigital twinClinical scenariosDigital twin technologyMulti-modal dataProcedural planningDiagnostic workflowDisease phenotypePatient careTransforming Cardiovascular Care With Artificial Intelligence: From Discovery to Practice JACC State-of-the-Art Review
Khera R, Oikonomou E, Nadkarni G, Morley J, Wiens J, Butte A, Topol E. Transforming Cardiovascular Care With Artificial Intelligence: From Discovery to Practice JACC State-of-the-Art Review. Journal Of The American College Of Cardiology 2024, 84: 97-114. PMID: 38925729, PMCID: PMC12204085, DOI: 10.1016/j.jacc.2024.05.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsArtificial Intelligence for Cardiovascular Care—Part 1: Advances JACC Review Topic of the Week
Elias P, Jain S, Poterucha T, Randazzo M, Lopez Jimenez F, Khera R, Perez M, Ouyang D, Pirruccello J, Salerno M, Einstein A, Avram R, Tison G, Nadkarni G, Natarajan V, Pierson E, Beecy A, Kumaraiah D, Haggerty C, Avari Silva J, Maddox T. Artificial Intelligence for Cardiovascular Care—Part 1: Advances JACC Review Topic of the Week. Journal Of The American College Of Cardiology 2024, 83: 2472-2486. PMID: 38593946, DOI: 10.1016/j.jacc.2024.03.400.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsEnhanced image qualityHuman expertsLeverage AIEvaluation benchmarkArtificial intelligenceAI modelsAI advancementsDetect diseaseTraining methodsImage qualityReduced ejection fractionEvolving technologyValvular heart diseaseReal-world efficacyEjection fractionProvider experienceHeart diseaseTechnologyCardiovascular carePatient careUnique characteristicsIntelligenceBenchmarks
2022
Rural-Urban Disparities in Heart Failure and Acute Myocardial Infarction Hospitalizations
Minhas AMK, Sheikh AB, Ijaz SH, Mostafa A, Nazir S, Khera R, Loccoh EC, Warraich HJ. Rural-Urban Disparities in Heart Failure and Acute Myocardial Infarction Hospitalizations. The American Journal Of Cardiology 2022, 175: 164-169. PMID: 35577603, DOI: 10.1016/j.amjcard.2022.04.014.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHeart failureHospital mortalityUrban hospitalRural hospitalsInflation-adjusted costStudy periodAMI hospitalizationMortality gapNational Inpatient SampleLength of stayAcute myocardial infarction hospitalizationsShorter mean lengthMyocardial infarction hospitalizationsHF hospitalizationCardiovascular outcomesClinical outcomesConsistent decreaseMyocardial infarctionInpatient SampleRural-urban disparitiesCardiovascular careHospitalizationHospitalMean length
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