International Validation of Echocardiographic Artificial Intelligence Amyloid Detection Algorithm
Duffy G, Oikonomou E, Easton N, Usuku H, Patel J, Katsumata Y, Yamasawa D, Stern L, Goto S, Tsujita K, Cheng P, Khera R, Ahmad F, Ouyang D. International Validation of Echocardiographic Artificial Intelligence Amyloid Detection Algorithm. JACC Advances 2025, 102067. PMID: 40965401, DOI: 10.1016/j.jacadv.2025.102067.Peer-Reviewed Original ResearchPositive predictive valueCardiac amyloidosisReceiver operating characteristic curveArea under the receiver operating characteristic curveOperating characteristics curvePredictive valueDiagnosis of cardiac amyloidosisAccurate diagnosisRetrospective case-control studyGlobal longitudinal strainLeft ventricular wall thicknessNegative predictive valueDiagnosis of CACharacteristic curveVentricular wall thicknessBody mass indexParasternal long axisTransthoracic echocardiographic measurementsCase-control studyCA patientsVentricular hypertrophyEchocardiographic measurementsEchocardiogram studyCA subtypesMass indexEnsemble Deep Learning Algorithm for Structural Heart Disease Screening Using Electrocardiographic Images PRESENT SHD
Dhingra L, Aminorroaya A, Sangha V, Pedroso A, Shankar S, Coppi A, Foppa M, Brant L, Barreto S, Ribeiro A, Krumholz H, Oikonomou E, Khera R. Ensemble Deep Learning Algorithm for Structural Heart Disease Screening Using Electrocardiographic Images PRESENT SHD. Journal Of The American College Of Cardiology 2025, 85: 1302-1313. PMID: 40139886, PMCID: PMC12199746, DOI: 10.1016/j.jacc.2025.01.030.Peer-Reviewed Original ResearchConceptsStructural heart diseaseYale-New Haven HospitalTransthoracic echocardiogramRisk stratificationHeart failureLeft-sided valvular diseaseSevere left ventricular hypertrophyLeft ventricular ejection fractionReceiver-operating characteristic curveVentricular ejection fractionLeft ventricular hypertrophyHeart disease screeningELSA-BrasilEnsemble deep learning algorithmRisk of deathConvolutional neural network modelEjection fractionEnsemble deep learning approachVentricular hypertrophyDeep learning algorithmsNew Haven HospitalDeep learning approachValvular diseaseNeural network modelClinical cohort
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