Featured Publications
Detection of left ventricular systolic dysfunction from single-lead electrocardiography adapted for portable and wearable devices
Khunte A, Sangha V, Oikonomou E, Dhingra L, Aminorroaya A, Mortazavi B, Coppi A, Brandt C, Krumholz H, Khera R. Detection of left ventricular systolic dysfunction from single-lead electrocardiography adapted for portable and wearable devices. Npj Digital Medicine 2023, 6: 124. PMID: 37433874, PMCID: PMC10336107, DOI: 10.1038/s41746-023-00869-w.Peer-Reviewed Original ResearchArtificial intelligenceRandom Gaussian noiseNoisy electrocardiogramGaussian noiseElectrocardiogram (ECGWearable devicesSingle-lead electrocardiogramPortable devicesSNRWearableNoiseDevice noiseRepositoryAI-based screeningIntelligenceDetectionDevicesNoise sourcesVentricular systolic dysfunctionModelElectrocardiogramSingle-lead electrocardiographyTrainingDetection of Left Ventricular Systolic Dysfunction From Electrocardiographic Images
Sangha V, Nargesi A, Dhingra L, Khunte A, Mortazavi B, Ribeiro A, Banina E, Adeola O, Garg N, Brandt C, Miller E, Ribeiro A, Velazquez E, Giatti L, Barreto S, Foppa M, Yuan N, Ouyang D, Krumholz H, Khera R. Detection of Left Ventricular Systolic Dysfunction From Electrocardiographic Images. Circulation 2023, 148: 765-777. PMID: 37489538, PMCID: PMC10982757, DOI: 10.1161/circulationaha.122.062646.Peer-Reviewed Original ResearchConceptsLV systolic dysfunctionYale-New Haven HospitalVentricular systolic dysfunctionSystolic dysfunctionLV ejection fractionBrazilian Longitudinal StudyNew Haven HospitalEjection fractionCardiology clinicRegional hospitalLeft ventricular systolic dysfunctionCedars-Sinai Medical CenterAdult Health (ELSA-Brasil) cohort
2023
DEEP LEARNING-BASED DETECTION OF LEFT VENTRICULAR SYSTOLIC DYSFUNCTION FROM NOISY SINGLE LEAD ELECTROCARDIOGRAPHY ADAPTED FOR WEARABLE DEVICES
Khunte A, Sangha V, Dhingra L, Oikonomou E, Mortazavi B, Khera R. DEEP LEARNING-BASED DETECTION OF LEFT VENTRICULAR SYSTOLIC DYSFUNCTION FROM NOISY SINGLE LEAD ELECTROCARDIOGRAPHY ADAPTED FOR WEARABLE DEVICES. Journal Of The American College Of Cardiology 2023, 81: 2262. DOI: 10.1016/s0735-1097(23)02706-7.Peer-Reviewed Original ResearchLeft ventricular systolic dysfunctionVentricular systolic dysfunctionSingle-lead electrocardiographySystolic dysfunctionLead electrocardiography
2019
Diagnostic and prognostic utility of cardiac troponin in post-cardiac arrest care
Agusala V, Khera R, Cheeran D, Mody P, Reddy PP, Link MS. Diagnostic and prognostic utility of cardiac troponin in post-cardiac arrest care. Resuscitation 2019, 141: 69-72. PMID: 31201884, DOI: 10.1016/j.resuscitation.2019.06.004.Peer-Reviewed Original ResearchConceptsLeft ventricular systolic dysfunctionIschemic etiologyInitial cTnTPeak cTnTCardiac troponinPost-cardiac arrest settingRetrospective single-center registryPost-cardiac arrest careVentricular systolic dysfunctionSingle-center registryTroponin T testingSystolic dysfunctionCenter registryConsecutive patientsSpontaneous circulationArrest carePrognostic utilityCardiac arrestMean agePatient outcomesExpert adjudicationEtiologyCTnTDiagnostic testsT-testing
2015
Trends in hospitalization for takotsubo cardiomyopathy in the United States
Khera R, Light-McGroary K, Zahr F, Horwitz PA, Girotra S. Trends in hospitalization for takotsubo cardiomyopathy in the United States. American Heart Journal 2015, 172: 53-63. PMID: 26856216, PMCID: PMC4748175, DOI: 10.1016/j.ahj.2015.10.022.Peer-Reviewed Original ResearchConceptsTakotsubo cardiomyopathyPrimary diagnosis groupCardiac arrestDiagnosis groupsHigh incidenceCardiogenic shockRespiratory failurePsychiatric disordersTransient left ventricular systolic dysfunctionLeft ventricular systolic dysfunctionNational Inpatient Sample dataCardiovascular risk factorsDiagnostic coronary angiographyVentricular systolic dysfunctionSecondary discharge diagnosisRisk of mortalityCost of careHospital mortalitySystolic dysfunctionCritical illnessCoronary angiographyDischarge diagnosisRisk factorsExcess mortalitySecondary group