2024
Cognitive Behavioral Therapy and Lisdexamfetamine, Alone and Combined, for Binge-Eating Disorder With Obesity: A Randomized Controlled Trial.
Grilo C, Ivezaj V, Tek C, Yurkow S, Wiedemann A, Gueorguieva R. Cognitive Behavioral Therapy and Lisdexamfetamine, Alone and Combined, for Binge-Eating Disorder With Obesity: A Randomized Controlled Trial. American Journal Of Psychiatry 2024 PMID: 39659158, DOI: 10.1176/appi.ajp.20230982.Peer-Reviewed Original ResearchCognitive-behavioral therapyBinge-eating disorderEffectiveness of cognitive-behavioral therapyBinge-eating remission ratesEating-disorder psychopathologyCognitive behavioral therapyEvidence-based treatmentsRemission ratePercent weight lossHigher remission ratesBinge-eating frequencyBehavioral therapyPosttreatment assessmentLisdexamfetamineRandomized controlled trialsHeightened ratesCostly public health problemIntention-to-treat ratesFunctional impairmentWeight lossControlled trialsDisordersPosttreatmentIndividualized treatmentMixed modelsOvervaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder
Grilo C, Ivezaj V, Gueorguieva R. Overvaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder. International Journal Of Eating Disorders 2024, 57: 1268-1273. PMID: 38321617, PMCID: PMC11093697, DOI: 10.1002/eat.24141.Peer-Reviewed Original ResearchOvervaluation of shape/weightEating-disorder psychopathologyBinge-eating disorderEating Disorder Examination interviewBeck Depression InventoryWeight loss treatmentClinical overvaluationBinge-eating frequencyDiagnostic specifierBinge eatingNon-abstinenceExamination interviewDepression InventoryShape/weightDepression scoresFollow-upPsychopathologyAbstinenceBingeDepressionClinical implicationsDepression 1PosttreatmentDisordersOvervaluation
2022
24‐Month follow‐up of randomized controlled trial of guided‐self‐help for loss‐of‐control eating after bariatric surgery
Grilo CM, Ivezaj V, Duffy AJ, Gueorguieva R. 24‐Month follow‐up of randomized controlled trial of guided‐self‐help for loss‐of‐control eating after bariatric surgery. International Journal Of Eating Disorders 2022, 55: 1521-1531. PMID: 36054766, DOI: 10.1002/eat.23804.Peer-Reviewed Original ResearchConceptsBariatric surgeryHELP treatmentWeight gainLong-term effectsSuboptimal long-term outcomesModest weight lossProportion of patientsBariatric surgery outcomesSubgroup of patientsLong-term outcomesSignificant weight gainSubstantial weight gainEating-disorder psychopathologyPostoperative interventionsAdjunctive treatmentTreat analysisSurgery outcomesSpecialist treatmentLOC eatingPatientsSurgeryWeight lossTrial testingPosttreatmentTreatment
2020
Randomized Controlled Trial of Behavioral Weight Loss and Stepped Care for Binge‐Eating Disorder: 12‐Month Follow‐up
Grilo CM, White MA, Ivezaj V, Gueorguieva R. Randomized Controlled Trial of Behavioral Weight Loss and Stepped Care for Binge‐Eating Disorder: 12‐Month Follow‐up. Obesity 2020, 28: 2116-2124. PMID: 32985114, PMCID: PMC7644623, DOI: 10.1002/oby.22975.Peer-Reviewed Original ResearchConceptsBehavioral weight lossStepped careWeight lossWeight loss medicationsRandomized Controlled TrialsSignificant weight lossBinge-eating disorderBinge-eating frequencySignificant time effectBinge Eating DisorderCognitive behavioral therapyRemission rateControlled TrialsTreatment respondersLong-term effectsBehavioral therapyMixed modelsPatientsCareObesitySignificant reductionTreatmentMonthsPosttreatmentDisorders