2025
HSA Adductomics in the Shanghai Women’s Health Study Links Lung Cancer in Never-Smokers with Air Pollution, Redox Biology, and One-Carbon Metabolism
Imani P, Grigoryan H, Dudoit S, Shu X, Wong J, Zhang L, Zhang J, Hu W, Cai Q, Gao Y, Blechter B, Rahman M, Zheng W, Rothman N, Lan Q, Rappaport S. HSA Adductomics in the Shanghai Women’s Health Study Links Lung Cancer in Never-Smokers with Air Pollution, Redox Biology, and One-Carbon Metabolism. Antioxidants 2025, 14: 335. PMID: 40227422, PMCID: PMC11939640, DOI: 10.3390/antiox14030335.Peer-Reviewed Original ResearchPolycyclic aromatic hydrocarbonsNever-smokersAir pollutionLung cancerOne-carbon metabolismAirborne fine particulate matterLung adenocarcinomaUrinary polycyclic aromatic hydrocarbonsFine particulate matterShanghai Women's Health StudyWomen's Health StudySmoking-related cancersReactive oxygen speciesIncidence of lung adenocarcinomaAromatic hydrocarbonsLung cancer casesParticulate matterEast Asian womenHealth StudyCancer casesAsian womenDietary factorsPollutionHuman serum albuminHigher incidence
2024
Long-term exposure to particulate matter and all-cause and cause-specific mortality in an analysis of multiple Asian cohorts
Downward G, Hystad P, Tasmin S, Abe S, Saito E, Rahman M, Islam M, Gupta P, Sawada N, Malekzadeh R, You S, Ahsan H, Park S, Pednekar M, Tsugane S, Etemadi A, Chen C, Shin A, Chen Y, Boffetta P, Chia K, Matsuo K, Qiao Y, Rothman N, Zheng W, Inoue M, Kang D, Lan Q, Vermeulen R. Long-term exposure to particulate matter and all-cause and cause-specific mortality in an analysis of multiple Asian cohorts. Environment International 2024, 189: 108803. PMID: 38870578, DOI: 10.1016/j.envint.2024.108803.Peer-Reviewed Original ResearchCause-specific mortalityAmbient air pollutionAll-causeLong-term exposure to particulate matterExposure to ambient air pollutionHazard ratioAsia Cohort ConsortiumCause-specific hazard ratiosHealth Effects InstituteRandom-effects meta-analysisExposure to particulate matterYear of enrollmentCohort ConsortiumAir pollutionCox proportional modelsSmoking statusResidential informationMortality outcomesSecondary analysisEx-smokersParticulate matterCardiovascular mortalityEuropean cohortMeta-analysisAmbient particulate matter
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