2025
HSA Adductomics in the Shanghai Women’s Health Study Links Lung Cancer in Never-Smokers with Air Pollution, Redox Biology, and One-Carbon Metabolism
Imani P, Grigoryan H, Dudoit S, Shu X, Wong J, Zhang L, Zhang J, Hu W, Cai Q, Gao Y, Blechter B, Rahman M, Zheng W, Rothman N, Lan Q, Rappaport S. HSA Adductomics in the Shanghai Women’s Health Study Links Lung Cancer in Never-Smokers with Air Pollution, Redox Biology, and One-Carbon Metabolism. Antioxidants 2025, 14: 335. PMID: 40227422, PMCID: PMC11939640, DOI: 10.3390/antiox14030335.Peer-Reviewed Original ResearchPolycyclic aromatic hydrocarbonsNever-smokersAir pollutionLung cancerOne-carbon metabolismAirborne fine particulate matterLung adenocarcinomaUrinary polycyclic aromatic hydrocarbonsFine particulate matterShanghai Women's Health StudyWomen's Health StudySmoking-related cancersReactive oxygen speciesIncidence of lung adenocarcinomaAromatic hydrocarbonsLung cancer casesParticulate matterEast Asian womenHealth StudyCancer casesAsian womenDietary factorsPollutionHuman serum albuminHigher incidence
2024
Epigenome-wide association study of lung cancer among never-smokers in two prospective cohorts in Shanghai, China
Rahman M, Breeze C, Shu X, Wong J, Cardenas A, Wang X, Ji B, Hu W, Blechter B, Cai Q, Hosgood H, Yang G, Shi J, Long J, Gao Y, Bell D, Zheng W, Rothman N, Lan Q. Epigenome-wide association study of lung cancer among never-smokers in two prospective cohorts in Shanghai, China. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.1672.Peer-Reviewed Original ResearchA nested case‐control study of untargeted plasma metabolomics and lung cancer among never‐smoking women within the prospective Shanghai Women's Health Study
Rahman M, Shu X, Jones D, Hu W, Ji B, Blechter B, Wong J, Cai Q, Yang G, Gao Y, Zheng W, Rothman N, Walker D, Lan Q. A nested case‐control study of untargeted plasma metabolomics and lung cancer among never‐smoking women within the prospective Shanghai Women's Health Study. International Journal Of Cancer 2024, 155: 508-518. PMID: 38651675, PMCID: PMC11284831, DOI: 10.1002/ijc.34929.Peer-Reviewed Original ResearchShanghai Women's Health StudyProspective Shanghai Women's Health StudyNested case-control studyNever-smoking womenLung cancerWomen's Health StudyCase-control studyNever-smokersPlasma metabolomeLung adenocarcinomaRisk factorsPre-diagnostic plasmaHealth StudyLung cancer risk factorsMetabolic featuresCancer risk factorsCancer-free womenAssociated with lung adenocarcinomaFactors of lung cancerLung cancer pathogenesisRisk factors of lung cancerLung cancer casesConditional logistic regression modelsEtiology of lung cancerTraffic-related air pollution
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