2025
HSA Adductomics in the Shanghai Women’s Health Study Links Lung Cancer in Never-Smokers with Air Pollution, Redox Biology, and One-Carbon Metabolism
Imani P, Grigoryan H, Dudoit S, Shu X, Wong J, Zhang L, Zhang J, Hu W, Cai Q, Gao Y, Blechter B, Rahman M, Zheng W, Rothman N, Lan Q, Rappaport S. HSA Adductomics in the Shanghai Women’s Health Study Links Lung Cancer in Never-Smokers with Air Pollution, Redox Biology, and One-Carbon Metabolism. Antioxidants 2025, 14: 335. PMID: 40227422, PMCID: PMC11939640, DOI: 10.3390/antiox14030335.Peer-Reviewed Original ResearchPolycyclic aromatic hydrocarbonsNever-smokersAir pollutionLung cancerOne-carbon metabolismAirborne fine particulate matterLung adenocarcinomaUrinary polycyclic aromatic hydrocarbonsFine particulate matterShanghai Women's Health StudyWomen's Health StudySmoking-related cancersReactive oxygen speciesIncidence of lung adenocarcinomaAromatic hydrocarbonsLung cancer casesParticulate matterEast Asian womenHealth StudyCancer casesAsian womenDietary factorsPollutionHuman serum albuminHigher incidence
2024
Household air pollution and telomere length among women in Guatemala and Peru: the Household Air Pollution Intervention Network (HAPIN) trial
Salmons K, Keller K, Chang H, Chen Y, Jabbarzadeh S, Pillarisetti A, Young B, Steenland K, Mccracken J, Diaz Artiga A, Thompson L, Checkley W, Underhill L, Rothman N, Blechter B, Barr D, Peel J, Lan Q, Clark M. Household air pollution and telomere length among women in Guatemala and Peru: the Household Air Pollution Intervention Network (HAPIN) trial. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.1581.Peer-Reviewed Original ResearchExpanded PAH analysis of household air pollution in a rural region of China with high lung cancer incidence
Zhang Y, Meliefste K, Hu W, Portengen L, Rothman N, Reiss B, Li J, Xu J, Ning B, Liu D, Cassee F, Wong J, Vermeulen R, Lan Q, Downward G. Expanded PAH analysis of household air pollution in a rural region of China with high lung cancer incidence. Environmental Pollution 2024, 361: 124717. PMID: 39147225, DOI: 10.1016/j.envpol.2024.124717.Peer-Reviewed Original ResearchMethyl-PAHsHousehold air pollutionAir pollutionExposure assessmentReduce household air pollutionHuman carcinogenCoal combustion productsHighest lung cancer ratesDomestic combustionHigh lung cancer incidenceControlled burningStove typeStove ventilationHealth risksSmokeless coalRegions of ChinaStove useSuspected human carcinogensCoal sourcesFuel typeDriving factorsFuel transitionRural regions of ChinaSmoky coalPAHsLong-term exposure to particulate matter and all-cause and cause-specific mortality in an analysis of multiple Asian cohorts
Downward G, Hystad P, Tasmin S, Abe S, Saito E, Rahman M, Islam M, Gupta P, Sawada N, Malekzadeh R, You S, Ahsan H, Park S, Pednekar M, Tsugane S, Etemadi A, Chen C, Shin A, Chen Y, Boffetta P, Chia K, Matsuo K, Qiao Y, Rothman N, Zheng W, Inoue M, Kang D, Lan Q, Vermeulen R. Long-term exposure to particulate matter and all-cause and cause-specific mortality in an analysis of multiple Asian cohorts. Environment International 2024, 189: 108803. PMID: 38870578, DOI: 10.1016/j.envint.2024.108803.Peer-Reviewed Original ResearchCause-specific mortalityAmbient air pollutionAll-causeLong-term exposure to particulate matterExposure to ambient air pollutionHazard ratioAsia Cohort ConsortiumCause-specific hazard ratiosHealth Effects InstituteRandom-effects meta-analysisExposure to particulate matterYear of enrollmentCohort ConsortiumAir pollutionCox proportional modelsSmoking statusResidential informationMortality outcomesSecondary analysisEx-smokersParticulate matterCardiovascular mortalityEuropean cohortMeta-analysisAmbient particulate matter
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