2024
High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study
Rogne T, Wang R, Wang P, Deziel N, Metayer C, Wiemels J, Chen K, Warren J, Ma X. High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study. The Lancet Planetary Health 2024, 8: e506-e514. PMID: 38969477, PMCID: PMC11260908, DOI: 10.1016/s2542-5196(24)00121-9.Peer-Reviewed Original ResearchConceptsRisk of childhood acute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaLatino childrenNon-Latino white childrenAssociated with risk of adverse pregnancy outcomesCalifornia Cancer RegistryRisk of acute lymphoblastic leukemiaCalifornia birth recordsRisk of adverse pregnancy outcomesPre-pregnancy periodAssociated with riskBayesian meta-regressionNational Institutes of HealthCancer RegistryCases of childhood acute lymphoblastic leukemiaNational Center for Advancing Translational SciencesAdverse pregnancy outcomesAcute lymphoblastic leukemia casesInstitutes of HealthInvestigation of mechanistic pathwaysBirth recordsGestational weeks 8Pre-pregnancy
2023
Predictors of early life residential mobility in urban and rural Pennsylvania children with acute lymphoblastic leukemia and implications for environmental exposure assessment
Clark C, Warren J, Saiers J, Ma X, Bell M, Deziel N. Predictors of early life residential mobility in urban and rural Pennsylvania children with acute lymphoblastic leukemia and implications for environmental exposure assessment. Journal Of Exposure Science & Environmental Epidemiology 2023, 1-10. PMID: 38148338, DOI: 10.1038/s41370-023-00636-9.Peer-Reviewed Original ResearchPer- and polyfluoroalkyl substances (PFAS) and thyroid hormone measurements in dried blood spots and neonatal characteristics: a pilot study
Rosen Vollmar A, Lin E, Nason S, Santiago K, Johnson C, Ma X, Godri Pollitt K, Deziel N. Per- and polyfluoroalkyl substances (PFAS) and thyroid hormone measurements in dried blood spots and neonatal characteristics: a pilot study. Journal Of Exposure Science & Environmental Epidemiology 2023, 33: 737-747. PMID: 37730931, PMCID: PMC10541328, DOI: 10.1038/s41370-023-00603-4.Peer-Reviewed Original ResearchConceptsThyroid hormone concentrationsNeonatal characteristicsThyroid hormone measurementsHormone concentrationsThyroid hormonesBlood spotsPilot studyNewborn DBSHormone measurementsPopulation-based studyThyroid hormone levelsEnvironmental risk factorsPFAS concentrationsNewborn screening testNon-parametric WilcoxonThyroid diseaseRisk factorsHormone levelsKruskal-Wallis testPFAS exposureThyroid hormone dataScreening testNeonatal DBSEnvironmental exposuresPerformance liquid chromatography-mass spectrometry
2022
Assessing unconventional oil and gas exposure in the Appalachian Basin: Comparison of exposure surrogates and drinking water measurements in Ohio and Pennsylvania
Clark C, Xiong B, Soriano M, Gutchess K, Siegel H, Ryan E, Johnson N, Cassell K, Elliott E, Li Y, Cox A, Bugher N, Glist L, Brenneis R, Sorrentino K, Plano J, Ma X, Warren J, Plata D, Saiers J, Deziel N. Assessing unconventional oil and gas exposure in the Appalachian Basin: Comparison of exposure surrogates and drinking water measurements in Ohio and Pennsylvania. ISEE Conference Abstracts 2022, 2022 DOI: 10.1289/isee.2022.p-0833.Peer-Reviewed Original ResearchUnconventional oil and gas exposure and risk of childhood leukemia in Pennsylvania
Clark C, Johnson N, Soriano M, Warren J, Sorrentino K, Kadan-Lottick N, Saiers J, Ma X, Deziel N. Unconventional oil and gas exposure and risk of childhood leukemia in Pennsylvania. ISEE Conference Abstracts 2022, 2022 DOI: 10.1289/isee.2022.p-0436.Peer-Reviewed Original ResearchHemoglobin normalization outperforms other methods for standardizing dried blood spot metabolomics: A comparative study
Jain A, Morris M, Lin EZ, Khan SA, Ma X, Deziel NC, Godri Pollitt KJ, Johnson CH. Hemoglobin normalization outperforms other methods for standardizing dried blood spot metabolomics: A comparative study. The Science Of The Total Environment 2022, 854: 158716. PMID: 36113793, DOI: 10.1016/j.scitotenv.2022.158716.Peer-Reviewed Original ResearchUnconventional Oil and Gas Development Exposure and Risk of Childhood Acute Lymphoblastic Leukemia: A Case–Control Study in Pennsylvania, 2009–2017
Clark CJ, Johnson NP, Soriano M, Warren JL, Sorrentino KM, Kadan-Lottick NS, Saiers JE, Ma X, Deziel NC. Unconventional Oil and Gas Development Exposure and Risk of Childhood Acute Lymphoblastic Leukemia: A Case–Control Study in Pennsylvania, 2009–2017. Environmental Health Perspectives 2022, 130: 087001. PMID: 35975995, PMCID: PMC9383266, DOI: 10.1289/ehp11092.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaCase-control studyOdds ratioChildhood leukemiaLymphoblastic leukemiaPerinatal windowRegistry-based case-control studyChildhood acute lymphoblastic leukemiaConfidence intervalsResidential proximityChildren ages 2Risk factorsMaternal raceChild healthExposure windowsSocio-economic statusPotential associationLeukemiaLogistic regressionAge 2Birth yearCommon formBirth residenceDevelopment exposureOddsInternational patterns and trends of childhood and adolescent cancer, 1978-2012
Zhao Y, Sun P, Xiao J, Jin L, Ma N, Li Z, Feng G, Huang H, Deziel N, Ma X, Ni X, Zhang Y. International patterns and trends of childhood and adolescent cancer, 1978-2012. Journal Of The National Cancer Center 2022, 2: 78-89. PMID: 39034956, PMCID: PMC11256536, DOI: 10.1016/j.jncc.2022.02.001.Peer-Reviewed Original ResearchCancer incidence ratesIncidence rateCancer incidenceMalignant central nervous system tumorsCentral nervous system tumorsOverall childhood cancerIncidence of lymphomaNervous system tumorsLeukemia incidence ratesSystem tumorsTesticular cancerChildhood cancerThyroid cancerAdolescent cancerKidney cancerJoinpoint regressionCancer incidentsAge groupsCancerCancer typesIncidenceTemporal trendsMethods DataAdolescentsChildrenAssessing Unconventional Oil and Gas Exposure in the Appalachian Basin: Comparison of Exposure Surrogates and Residential Drinking Water Measurements
Clark CJ, Xiong B, Soriano MA, Gutchess K, Siegel HG, Ryan EC, Johnson NP, Cassell K, Elliott EG, Li Y, Cox AJ, Bugher N, Glist L, Brenneis RJ, Sorrentino KM, Plano J, Ma X, Warren JL, Plata DL, Saiers JE, Deziel NC. Assessing Unconventional Oil and Gas Exposure in the Appalachian Basin: Comparison of Exposure Surrogates and Residential Drinking Water Measurements. Environmental Science And Technology 2022, 56: 1091-1103. PMID: 34982938, PMCID: PMC10259677, DOI: 10.1021/acs.est.1c05081.Peer-Reviewed Original Research
2021
Community concern and government response: Identifying socio-economic and demographic predictors of oil and gas complaints and drinking water impairments in Pennsylvania
Clark CJ, Warren JL, Kadan-Lottick N, Ma X, Bell ML, Saiers JE, Deziel NC. Community concern and government response: Identifying socio-economic and demographic predictors of oil and gas complaints and drinking water impairments in Pennsylvania. Energy Research & Social Science 2021, 76: 102070. PMID: 34123731, PMCID: PMC8192069, DOI: 10.1016/j.erss.2021.102070.Peer-Reviewed Original Research
2020
Birth Characteristics and Risk of Pediatric Thyroid Cancer: A Population-Based Record-Linkage Study in California
Deziel N, Zhang Y, Wang R, Wiemels JL, Morimoto L, Clark CJ, Metayer C, Ma X. Birth Characteristics and Risk of Pediatric Thyroid Cancer: A Population-Based Record-Linkage Study in California. Thyroid 2020, 31: 596-606. PMID: 32912083, PMCID: PMC8195873, DOI: 10.1089/thy.2020.0217.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge of OnsetBirth CertificatesBirth OrderBirth WeightCaliforniaCase-Control StudiesChildChild, PreschoolEducational StatusFemaleHispanic or LatinoHumansIncidenceInfantInfant, NewbornMaleRace FactorsRegistriesRisk AssessmentRisk FactorsSex FactorsThyroid NeoplasmsTime FactorsYoung AdultConceptsPediatric thyroid cancerHigh birth weightFollicular thyroid cancerThyroid cancerHigher birth orderBirth characteristicsRisk factorsHispanic ethnicityBirth weightOdds ratioFirst primary thyroid cancerPapillary thyroid cancer casesBirth orderMultivariable logistic regression modelSecond primary malignanciesLong-term therapyAdjusted odds ratioPopulation-based studyPrimary thyroid cancerRecord linkage studyConfidence intervalsImportant risk factorCancer registry dataCase-control studyThyroid cancer cases
2018
A community-based evaluation of proximity to unconventional oil and gas wells, drinking water contaminants, and health symptoms in Ohio
Elliott EG, Ma X, Leaderer BP, McKay LA, Pedersen CJ, Wang C, Gerber CJ, Wright TJ, Sumner AJ, Brennan M, Silva GS, Warren JL, Plata DL, Deziel NC. A community-based evaluation of proximity to unconventional oil and gas wells, drinking water contaminants, and health symptoms in Ohio. Environmental Research 2018, 167: 550-557. PMID: 30145431, DOI: 10.1016/j.envres.2018.08.022.Peer-Reviewed Original Research
2016
Unconventional oil and gas development and risk of childhood leukemia: Assessing the evidence
Elliott EG, Trinh P, Ma X, Leaderer BP, Ward MH, Deziel NC. Unconventional oil and gas development and risk of childhood leukemia: Assessing the evidence. The Science Of The Total Environment 2016, 576: 138-147. PMID: 27783932, PMCID: PMC6457992, DOI: 10.1016/j.scitotenv.2016.10.072.Peer-Reviewed Original ResearchConceptsWater contaminantsPotential water contaminantsMajority of compoundsWater pollutantsPolycyclic aromatic hydrocarbonsHydraulic fracturing fluidsPollutantsAromatic hydrocarbonsAir pollutantsU.S. Environmental Protection AgencyCompoundsEnvironmental Protection AgencyPotential air pollutantsPossible human carcinogenContaminantsChemicalsCarcinogenicity of compoundsLeukemia/lymphomaProtection AgencyChildhood leukemiaWaterButadieneBenzeneFracturing fluidOilAssessing the potential link between chemical exposures from unconventional oil and gas development and risk of childhood leukemia
Elliott* E, Trinh P, Ma X, Leaderer B, Ward M, Deziel N. Assessing the potential link between chemical exposures from unconventional oil and gas development and risk of childhood leukemia. ISEE Conference Abstracts 2016, 2016 DOI: 10.1289/isee.2016.4602.Peer-Reviewed Original Research