2023
Per- and polyfluoroalkyl substances (PFAS) and thyroid hormone measurements in dried blood spots and neonatal characteristics: a pilot study
Rosen Vollmar A, Lin E, Nason S, Santiago K, Johnson C, Ma X, Godri Pollitt K, Deziel N. Per- and polyfluoroalkyl substances (PFAS) and thyroid hormone measurements in dried blood spots and neonatal characteristics: a pilot study. Journal Of Exposure Science & Environmental Epidemiology 2023, 33: 737-747. PMID: 37730931, PMCID: PMC10541328, DOI: 10.1038/s41370-023-00603-4.Peer-Reviewed Original ResearchMeSH KeywordsAlkanesulfonic AcidsChildEnvironmental ExposureEnvironmental PollutantsFluorocarbonsHumansInfant, NewbornPilot ProjectsThyroid HormonesConceptsThyroid hormone concentrationsNeonatal characteristicsThyroid hormone measurementsHormone concentrationsThyroid hormonesBlood spotsPilot studyNewborn DBSHormone measurementsPopulation-based studyThyroid hormone levelsEnvironmental risk factorsPFAS concentrationsNewborn screening testNon-parametric WilcoxonThyroid diseaseRisk factorsHormone levelsKruskal-Wallis testPFAS exposureThyroid hormone dataScreening testNeonatal DBSEnvironmental exposuresPerformance liquid chromatography-mass spectrometry
2022
Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Facial Features at 5 Years of Age: A Study from the Danish National Birth Cohort
Luo J, Ramlau-Hansen CH, Kesmodel US, Xiao J, Vasiliou V, Deziel NC, Zhang Y, Olsen J, Liew Z. Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Facial Features at 5 Years of Age: A Study from the Danish National Birth Cohort. Environmental Health Perspectives 2022, 130: 017006. PMID: 35080464, PMCID: PMC8791068, DOI: 10.1289/ehp9478.Peer-Reviewed Original ResearchMeSH KeywordsAlkanesulfonic AcidsBirth CohortChildDenmarkEnvironmental PollutantsFemaleFetal DevelopmentFluorocarbonsHumansMalePregnancyPrenatal Exposure Delayed EffectsConceptsDanish National Birth CohortMaternal alcohol intakePrenatal PFAS exposurePalpebral fissure lengthShorter palpebral fissure lengthNational Birth CohortYears of agePFAS exposureSecond tertileAlcohol intakePrenatal exposureOdds ratioBirth cohortSpecific neurologic deficitsConfidence intervalsFetal brain developmentSex-specific associationsNeurologic deficitsFirst trimesterPotential confoundersNeurodevelopmental effectsAlcohol exposureStratified analysisNormal groupMultinomial logistic regression
2020
Exposure to polychlorinated biphenyls and organochlorine pesticides and thyroid cancer in connecticut women
Deziel NC, Warren JL, Huang H, Zhou H, Sjodin A, Zhang Y. Exposure to polychlorinated biphenyls and organochlorine pesticides and thyroid cancer in connecticut women. Environmental Research 2020, 192: 110333. PMID: 33068584, PMCID: PMC7736223, DOI: 10.1016/j.envres.2020.110333.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancerThyroid cancerPCBs/OCPsOdds ratioSubsequent thyroid cancer riskMulti-pollutant modelingSerum Polychlorinated BiphenylsBody mass indexConfidence intervalsThyroid cancer riskThyroid cancer incidenceEarly life exposureEnvironmental risk factorsSingle-pollutant modelsLogistic regression modelsIsotope dilution high-resolution mass spectrometryMass indexTumor sizeCancer incidenceRisk factorsConnecticut womenFamily historyMulti-pollutant analysisCancer riskThyroid hormone disruptorsPrenatal exposure to perfluoroalkyl substances and behavioral difficulties in childhood at 7 and 11 years
Luo J, Xiao J, Gao Y, Ramlau-Hansen CH, Toft G, Li J, Obel C, Andersen SL, Deziel NC, Tseng WL, Inoue K, Bonefeld-Jørgensen EC, Olsen J, Liew Z. Prenatal exposure to perfluoroalkyl substances and behavioral difficulties in childhood at 7 and 11 years. Environmental Research 2020, 191: 110111. PMID: 32846178, PMCID: PMC7657987, DOI: 10.1016/j.envres.2020.110111.Peer-Reviewed Original ResearchMeSH KeywordsChildEnvironmental PollutantsFemaleFluorocarbonsHumansPregnancyPrenatal Exposure Delayed EffectsThyroid HormonesThyrotropinConceptsPrenatal PFAS exposureMaternal thyroid hormonesThyroid hormonesOdds ratioPFAS exposureDanish National Birth CohortMaternal thyroid functionPrenatal perfluoroalkyl substancesMaternal thyroid dysfunctionFree thyroxine levelsNational Birth CohortAdjusted odds ratioBehavioral difficultiesPerfluoroalkyl substancesNatural indirect effectThyroid dysfunctionPFNA exposureFetal neurodevelopmentPrenatal exposureEpidemiological evidenceThyroid functionEarly gestationThyroxine levelsBirth cohortMaternal plasma
2019
Exposure to Polybrominated Diphenyl Ethers and a Polybrominated Biphenyl and Risk of Thyroid Cancer in Women: Single and Multi-Pollutant Approaches
Deziel NC, Alfonso-Garrido J, Warren JL, Huang H, Sjodin A, Zhang Y. Exposure to Polybrominated Diphenyl Ethers and a Polybrominated Biphenyl and Risk of Thyroid Cancer in Women: Single and Multi-Pollutant Approaches. Cancer Epidemiology Biomarkers & Prevention 2019, 28: 1755-1764. PMID: 31387967, PMCID: PMC6774868, DOI: 10.1158/1055-9965.epi-19-0526.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancerThyroid cancerPTC riskLipid-adjusted serum concentrationsPapillary thyroid cancer casesMulti-pollutant approachSerum samplesMulti-pollutant modelingThyroid cancer incidenceInterquartile range increaseThyroid cancer casesMulti-pollutant modelsSingle-pollutant modelsLogistic regression modelsPBB exposureDecreased riskProspective studySerum concentrationsCancer incidenceCancer casesAlcohol consumptionFemale controlsLow categoryConfidence intervalsPBB mixture
2015
A Review of Nonoccupational Pathways for Pesticide Exposure in Women Living in Agricultural Areas
Deziel NC, Friesen MC, Hoppin JA, Hines CJ, Thomas K, Freeman LE. A Review of Nonoccupational Pathways for Pesticide Exposure in Women Living in Agricultural Areas. Environmental Health Perspectives 2015, 123: 515-524. PMID: 25636067, PMCID: PMC4455586, DOI: 10.1289/ehp.1408273.Peer-Reviewed Original ResearchMeSH KeywordsAgricultureEnvironmental ExposureEnvironmental PollutantsFemaleHumansNorth AmericaPesticides
2014
Residential Levels of Polybrominated Diphenyl Ethers and Risk of Childhood Acute Lymphoblastic Leukemia in California
Ward MH, Colt JS, Deziel NC, Whitehead TP, Reynolds P, Gunier RB, Nishioka M, Dahl GV, Rappaport SM, Buffler PA, Metayer C. Residential Levels of Polybrominated Diphenyl Ethers and Risk of Childhood Acute Lymphoblastic Leukemia in California. Environmental Health Perspectives 2014, 122: 1110-1116. PMID: 24911217, PMCID: PMC4181922, DOI: 10.1289/ehp.1307602.Peer-Reviewed Original ResearchConceptsOdds ratioChildhood acute lymphoblastic leukemiaBirth certificate controlsNorthern California Childhood Leukemia StudyAcute lymphoblastic leukemiaCalifornia Childhood Leukemia StudyYears of ageChildhood Leukemia StudyRace/ethnicityDate of birthLymphoblastic leukemiaLogistic regressionLeukemia StudyAdditional studiesHigh volume small surface samplerBDE-203House dustCommon PBDEsPositive associationBDE-207AssociationBiological measuresRiskBDE-99BDE-196
2013
Environmental Determinants of Polychlorinated Biphenyl Concentrations in Residential Carpet Dust
DellaValle CT, Wheeler DC, Deziel NC, De Roos AJ, Cerhan JR, Cozen W, Severson RK, Flory AR, Locke SJ, Colt JS, Hartge P, Ward MH. Environmental Determinants of Polychlorinated Biphenyl Concentrations in Residential Carpet Dust. Environmental Science And Technology 2013, 47: 10405-10414. PMID: 23952055, PMCID: PMC4076890, DOI: 10.1021/es401447w.Peer-Reviewed Original Research
2011
Comparison of wipe materials and wetting agents for pesticide residue collection from hard surfaces
Deziel NC, Viet SM, Rogers JW, Camann DE, Marker DA, Heikkinen MS, Yau AY, Stout DM, Dellarco M. Comparison of wipe materials and wetting agents for pesticide residue collection from hard surfaces. The Science Of The Total Environment 2011, 409: 4442-4448. PMID: 21816452, PMCID: PMC3178880, DOI: 10.1016/j.scitotenv.2011.07.002.Peer-Reviewed Original Research