2022
Unconventional Oil and Gas Development Exposure and Risk of Childhood Acute Lymphoblastic Leukemia: A Case–Control Study in Pennsylvania, 2009–2017
Clark CJ, Johnson NP, Soriano M, Warren JL, Sorrentino KM, Kadan-Lottick NS, Saiers JE, Ma X, Deziel NC. Unconventional Oil and Gas Development Exposure and Risk of Childhood Acute Lymphoblastic Leukemia: A Case–Control Study in Pennsylvania, 2009–2017. Environmental Health Perspectives 2022, 130: 087001. PMID: 35975995, PMCID: PMC9383266, DOI: 10.1289/ehp11092.Peer-Reviewed Original ResearchMeSH KeywordsCase-Control StudiesChildChild, PreschoolFemaleHumansOdds RatioPennsylvaniaPrecursor Cell Lymphoblastic Leukemia-LymphomaPregnancyRisk FactorsWaterConceptsAcute lymphoblastic leukemiaCase-control studyOdds ratioChildhood leukemiaLymphoblastic leukemiaPerinatal windowRegistry-based case-control studyChildhood acute lymphoblastic leukemiaConfidence intervalsResidential proximityChildren ages 2Risk factorsMaternal raceChild healthExposure windowsSocio-economic statusPotential associationLeukemiaLogistic regressionAge 2Birth yearCommon formBirth residenceDevelopment exposureOdds
2020
Birth Characteristics and Risk of Pediatric Thyroid Cancer: A Population-Based Record-Linkage Study in California
Deziel N, Zhang Y, Wang R, Wiemels JL, Morimoto L, Clark CJ, Metayer C, Ma X. Birth Characteristics and Risk of Pediatric Thyroid Cancer: A Population-Based Record-Linkage Study in California. Thyroid 2020, 31: 596-606. PMID: 32912083, PMCID: PMC8195873, DOI: 10.1089/thy.2020.0217.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge of OnsetBirth CertificatesBirth OrderBirth WeightCaliforniaCase-Control StudiesChildChild, PreschoolEducational StatusFemaleHispanic or LatinoHumansIncidenceInfantInfant, NewbornMaleRace FactorsRegistriesRisk AssessmentRisk FactorsSex FactorsThyroid NeoplasmsTime FactorsYoung AdultConceptsPediatric thyroid cancerHigh birth weightFollicular thyroid cancerThyroid cancerHigher birth orderBirth characteristicsRisk factorsHispanic ethnicityBirth weightOdds ratioFirst primary thyroid cancerPapillary thyroid cancer casesBirth orderMultivariable logistic regression modelSecond primary malignanciesLong-term therapyAdjusted odds ratioPopulation-based studyPrimary thyroid cancerRecord linkage studyConfidence intervalsImportant risk factorCancer registry dataCase-control studyThyroid cancer cases
2019
Genetic susceptibility may modify the association between cell phone use and thyroid cancer: A population-based case-control study in Connecticut
Luo J, Li H, Deziel NC, Huang H, Zhao N, Ma S, Ni X, Udelsman R, Zhang Y. Genetic susceptibility may modify the association between cell phone use and thyroid cancer: A population-based case-control study in Connecticut. Environmental Research 2019, 182: 109013. PMID: 31918310, PMCID: PMC7061309, DOI: 10.1016/j.envres.2019.109013.Peer-Reviewed Original ResearchExposure to Polybrominated Diphenyl Ethers and a Polybrominated Biphenyl and Risk of Thyroid Cancer in Women: Single and Multi-Pollutant Approaches
Deziel NC, Alfonso-Garrido J, Warren JL, Huang H, Sjodin A, Zhang Y. Exposure to Polybrominated Diphenyl Ethers and a Polybrominated Biphenyl and Risk of Thyroid Cancer in Women: Single and Multi-Pollutant Approaches. Cancer Epidemiology Biomarkers & Prevention 2019, 28: 1755-1764. PMID: 31387967, PMCID: PMC6774868, DOI: 10.1158/1055-9965.epi-19-0526.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancerThyroid cancerPTC riskLipid-adjusted serum concentrationsPapillary thyroid cancer casesMulti-pollutant approachSerum samplesMulti-pollutant modelingThyroid cancer incidenceInterquartile range increaseThyroid cancer casesMulti-pollutant modelsSingle-pollutant modelsLogistic regression modelsPBB exposureDecreased riskProspective studySerum concentrationsCancer incidenceCancer casesAlcohol consumptionFemale controlsLow categoryConfidence intervalsPBB mixture
2018
Cell phone use and risk of thyroid cancer: a population-based case–control study in Connecticut
Luo J, Deziel NC, Huang H, Chen Y, Ni X, Ma S, Udelsman R, Zhang Y. Cell phone use and risk of thyroid cancer: a population-based case–control study in Connecticut. Annals Of Epidemiology 2018, 29: 39-45. PMID: 30446214, PMCID: PMC6344271, DOI: 10.1016/j.annepidem.2018.10.004.Peer-Reviewed Original ResearchConceptsPopulation-based case-control studyCase-control studyThyroid cancerThyroid microcarcinomaOdds ratioUnconditional logistic regressionPopulation-based controlsThyroid cancer casesWarrants further investigationCancer casesSuggestive increaseElevated riskCell phone useSignificant associationCancerLogistic regressionMicrocarcinomaMore frequent usersConfidence intervalsRiskFrequent usersPhone useFurther investigationAssociationHoursAlcohol Consumption and Risk of Thyroid Cancer: A Population Based Case-Control Study in Connecticut
Huang H, Zhao N, Chen Y, Deziel N, Dai M, Li N, Udelsman R, Zhang Y. Alcohol Consumption and Risk of Thyroid Cancer: A Population Based Case-Control Study in Connecticut. Advances In Experimental Medicine And Biology 2018, 1032: 1-14. PMID: 30362087, DOI: 10.1007/978-3-319-98788-0_1.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol DrinkingCase-Control StudiesConnecticutHumansLogistic ModelsRisk FactorsThyroid NeoplasmsConceptsCase-control studyThyroid cancerAlcohol consumptionInverse associationPopulation Based Case-Control StudyPopulation-based case-control studyIncident thyroid cancer casesSignificant associationLager tumor sizeBody mass indexBenign thyroid diseaseUnconditional logistic regressionPopulation-based controlsThyroid cancer riskFirst-degree relativesPapillary thyroid cancerThyroid cancer casesPotential confounding variablesDose-dependent mannerConsumption of alcoholSmoking statusMass indexTumor sizeThyroid diseaseThyroid microcarcinomaA case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women
Deziel NC, Yi H, Stapleton HM, Huang H, Zhao N, Zhang Y. A case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women. BMC Cancer 2018, 18: 637. PMID: 29871608, PMCID: PMC5989427, DOI: 10.1186/s12885-018-4553-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCase-Control StudiesConnecticutEnvironmental ExposureFemaleFlame RetardantsHumansMiddle AgedOrganophosphatesThyroid Cancer, PapillaryConceptsCase-control studyThyroid cancer riskPFR exposureThyroid cancerPFR metabolitesOdds ratioCancer riskPapillary thyroid cancer casesUrinary biomarker measurementsTime of diagnosisLarger tumor sizeCancer case-control studySpot urine samplesThyroid cancer casesPapillary thyroid cancer riskTumor sizePotential confoundersThyroid hormone regulationUrinary concentrationsCancer casesMultiple linear regression analysisFemale controlsLinear regression analysisBackgroundGrowing evidenceBiomarker measurements
2017
Occupational exposure to pesticides and other biocides and risk of thyroid cancer
Zeng F, Lerro C, Lavoué J, Huang H, Siemiatycki J, Zhao N, Ma S, Deziel NC, Friesen MC, Udelsman R, Zhang Y. Occupational exposure to pesticides and other biocides and risk of thyroid cancer. Occupational And Environmental Medicine 2017, 74: 502. PMID: 28202579, PMCID: PMC5572578, DOI: 10.1136/oemed-2016-103931.Peer-Reviewed Original ResearchConceptsThyroid cancerOccupational exposurePopulation-based case-control studyIncident thyroid cancer casesUnconditional logistic regression modelsCase-control studyPapillary thyroid cancerThyroid cancer casesJob-exposure matrixLogistic regression modelsHigher cumulative probabilityPotential confoundersThyroid microcarcinomaCancer casesHigh riskSignificant associationCancerObserved associationsCumulative probabilityStrong associationRiskAssociationExposureFurther investigationRegression models
2016
Comparison of industrial emissions and carpet dust concentrations of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in a multi-center U.S. study
Deziel NC, Nuckols JR, Jones RR, Graubard BI, De Roos AJ, Pronk A, Gourley C, Colt JS, Ward MH. Comparison of industrial emissions and carpet dust concentrations of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in a multi-center U.S. study. The Science Of The Total Environment 2016, 580: 1276-1286. PMID: 28017415, PMCID: PMC5330683, DOI: 10.1016/j.scitotenv.2016.12.090.Peer-Reviewed Original ResearchConceptsMunicipal solid waste incineratorSolid waste incineratorMedical waste incineratorWaste incineratorEmission indexAverage emission indexSewage sludge incineratorsPCDD/F emissionsNon-hazardous wasteElectricity generating plantsPCDD/F congenersDust concentrationPCDD/F emission sourcesCement kilnsSludge incineratorsToxic PCDD/F congenersGenerating plantsEmission sourcesHazardous waste incineratorIncineratorF emissionsLocal meteorological dataNearby emission sourcesTerrain characteristicsSystem readings
2015
Polycyclic aromatic hydrocarbons: determinants of residential carpet dust levels and risk of non-Hodgkin lymphoma
DellaValle CT, Deziel NC, Jones RR, Colt JS, De Roos AJ, Cerhan JR, Cozen W, Severson RK, Flory AR, Morton LM, Ward MH. Polycyclic aromatic hydrocarbons: determinants of residential carpet dust levels and risk of non-Hodgkin lymphoma. Cancer Causes & Control 2015, 27: 1-13. PMID: 26573845, PMCID: PMC5358542, DOI: 10.1007/s10552-015-0660-y.Peer-Reviewed Original ResearchConceptsNon-Hodgkin lymphomaT-cell lymphomaOdds ratioCell lymphomaRisk of NHLNational Cancer Institute's Surveillance EpidemiologyMulticenter case-control studyB-cell lymphoma subtypesUnconditional logistic regressionCase-control studyConfidence intervalsHighest tertileLowest tertileHistologic typeSurveillance EpidemiologyNHL overallLymphoma subtypesWhite raceElevated riskSecondary aimConclusionOur resultsLymphomaOlder ageTertileLogistic regressionAssociations between self-reported pest treatments and pesticide concentrations in carpet dust
Deziel NC, Colt JS, Kent EE, Gunier RB, Reynolds P, Booth B, Metayer C, Ward MH. Associations between self-reported pest treatments and pesticide concentrations in carpet dust. Environmental Health 2015, 14: 27. PMID: 25889489, PMCID: PMC4374193, DOI: 10.1186/s12940-015-0015-x.Peer-Reviewed Original ResearchConceptsWeed treatmentsPest treatmentsPesticide concentrationsCarpet dust samplesPesticide active ingredientsAgricultural pesticide applicationsSelf-reported treatmentPesticide useResidential pesticide useTick treatmentPest typesPesticide applicationCypermethrin levelsHerbicide concentrationsPesticide categoriesGarden productsProfessional applicators
2014
Polycyclic aromatic hydrocarbons in residential dust and risk of childhood acute lymphoblastic leukemia
Deziel NC, Rull RP, Colt JS, Reynolds P, Whitehead TP, Gunier RB, Month SR, Taggart DR, Buffler P, Ward MH, Metayer C. Polycyclic aromatic hydrocarbons in residential dust and risk of childhood acute lymphoblastic leukemia. Environmental Research 2014, 133: 388-395. PMID: 24948546, PMCID: PMC4119528, DOI: 10.1016/j.envres.2014.04.033.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaLymphoblastic leukemiaOdds ratioPopulation-based case-control studyDiagnosis/reference datePAH exposureRisk of childhoodConfidence intervalsCase-control studyResidential dustVacuum dustLog-transformed concentrationsLogistic regressionProbable human carcinogenHigh volume small surface samplerDemographic characteristics
2013
Environmental Determinants of Polychlorinated Biphenyl Concentrations in Residential Carpet Dust
DellaValle CT, Wheeler DC, Deziel NC, De Roos AJ, Cerhan JR, Cozen W, Severson RK, Flory AR, Locke SJ, Colt JS, Hartge P, Ward MH. Environmental Determinants of Polychlorinated Biphenyl Concentrations in Residential Carpet Dust. Environmental Science And Technology 2013, 47: 10405-10414. PMID: 23952055, PMCID: PMC4076890, DOI: 10.1021/es401447w.Peer-Reviewed Original Research
2012
Comparability and repeatability of methods for estimating the dietary intake of the heterocyclic amine contaminant 2-amino-1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP)
Deziel NC, Buckley TJ, Sinha R, Abubaker S, Platz EA, Strickland PT. Comparability and repeatability of methods for estimating the dietary intake of the heterocyclic amine contaminant 2-amino-1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP). Food Additives & Contaminants Part A 2012, 29: 1202-1211. PMID: 22571725, PMCID: PMC3412362, DOI: 10.1080/19440049.2012.682657.Peer-Reviewed Original ResearchConceptsIntraclass correlation coefficientPhIP intakeUrinary PhIPDietary Heterocyclic Amine ExposureHeterocyclic amine exposureFull study populationSubject variabilityExposure assessment methodsBiomarker-based approachDiary-based estimatesSpearman correlation coefficientDietary intakeStudy populationEpidemiologic studiesLong-term exposureHCA 2Intake estimatesAmine exposurePhIP concentrationIntakePhIPInconsistent riskTerm exposureAssessment toolDiary collection
2011
Comparison of Standard Methods for Assessing Dietary Intake of Benzo[a]pyrene
Deziel NC, Strickland PT, Platz EA, Abubaker S, Buckley TJ. Comparison of Standard Methods for Assessing Dietary Intake of Benzo[a]pyrene. Cancer Epidemiology Biomarkers & Prevention 2011, 20: 962-970. PMID: 21430297, PMCID: PMC4618457, DOI: 10.1158/1055-9965.epi-10-1344.Peer-Reviewed Original ResearchConceptsFood frequency questionnaireBaP intakeExposure assessment methodsDiet diariesMeat intakeResidue databaseFrequency questionnaireStrength of associationDietary intakeNondietary exposureConsiderable unexplained variabilityBiomarker measurementsIntakeLimited correlationSpearman correlationCancerInconsistent presenceBaselineExposureInterpersonal variabilityStandard methodsDiaryNonsmokersUnexplained variabilityAssessment methods