2020
Challenging the concept of de novo acute myeloid leukemia: Environmental and occupational leukemogens hiding in our midst
Shallis RM, Weiss JJ, Deziel NC, Gore SD. Challenging the concept of de novo acute myeloid leukemia: Environmental and occupational leukemogens hiding in our midst. Blood Reviews 2020, 47: 100760. PMID: 32988660, DOI: 10.1016/j.blre.2020.100760.Peer-Reviewed Original ResearchConceptsAcute myeloid leukemiaDe novo acute myeloid leukemiaNovo acute myeloid leukemiaMyeloid leukemiaRisk of AMLTherapy-related acute myeloid leukemiaParticular chemotherapeutic agentsOccupational exposureIndividual patientsMyeloid neoplasmsGermline predispositionAccidental exposureLeukemogenChemotherapeutic agentsMarrow microenvironmentLeukemiaEnvironmental agentsAcceptable exposure limitsCell acquisitionPatientsExposure limitsExposureInescapable exposureAmbient exposureRisk
2017
Occupational exposure to pesticides and other biocides and risk of thyroid cancer
Zeng F, Lerro C, Lavoué J, Huang H, Siemiatycki J, Zhao N, Ma S, Deziel NC, Friesen MC, Udelsman R, Zhang Y. Occupational exposure to pesticides and other biocides and risk of thyroid cancer. Occupational And Environmental Medicine 2017, 74: 502. PMID: 28202579, PMCID: PMC5572578, DOI: 10.1136/oemed-2016-103931.Peer-Reviewed Original ResearchConceptsThyroid cancerOccupational exposurePopulation-based case-control studyIncident thyroid cancer casesUnconditional logistic regression modelsCase-control studyPapillary thyroid cancerThyroid cancer casesJob-exposure matrixLogistic regression modelsHigher cumulative probabilityPotential confoundersThyroid microcarcinomaCancer casesHigh riskSignificant associationCancerObserved associationsCumulative probabilityStrong associationRiskAssociationExposureFurther investigationRegression models