2024
Investigating Environmental Determinants of Hookworm Transmission using GPS Tracking and Metagenomics Technologies
Sumboh J, Agyenkwa-Mawuli K, Schwinger E, Donkor I, Akorli J, Dwomoh D, Ashong Y, Osabutey D, Ababio F, Nusbaum O, Humphries D, Cappello M, Koram K, Kwofie S, Wilson M. Investigating Environmental Determinants of Hookworm Transmission using GPS Tracking and Metagenomics Technologies. American Journal Of Tropical Medicine And Hygiene 2024, 112: 561-570. PMID: 39813691, PMCID: PMC11884298, DOI: 10.4269/ajtmh.24-0384.Peer-Reviewed Original ResearchConceptsEffective cation exchange capacityCation exchange capacitySandy-loam soilDominant helminth speciesSoil samplesClay contentSoil parametersExchange capacityHelminth larvaeAnalysis of DNA sequencesGPS trackingSoilParastrongyloides trichosuriAssociated with exposureLarvaeChemical propertiesPotential sourcesMovement dataSpeciesPredominant speciesHelminth speciesLarval countsMetagenomic technologiesDNA sequencesMetagenomic analysis
2005
Discovery and pre-clinical development of antithrombotics from hematophagous invertebrates.
Ledizet M, Harrison LM, Koskia RA, Cappello M. Discovery and pre-clinical development of antithrombotics from hematophagous invertebrates. Cardiovascular & Hematological Agents In Medicinal Chemistry 2005, 3: 1-10. PMID: 15638739, DOI: 10.2174/1568016052773315.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNumerous invertebrate speciesHematophagous invertebratesInvertebrate speciesSpecific inhibitorUnique specificityInvertebratesFunctional strategiesCritical roleImpressive arrayActivation of thrombosisUseful therapeutic agentPre-clinical developmentNatural productsInhibitorsPlatelet inhibitorsHeart diseaseHuman illnessPlatelet functionClinical developmentSpeciesTherapeutic agentsAntithromboticsParasitesBloodmealThrombosis
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